ARP 100 - Moligand™, ≥97% , Inhibitor of MMP2, CAS No.704888-90-4, Inhibitor of MMP2

CAS: 704888-90-4 Cat. No.: A287330 Formule: C17H20N2O5S Poids moléculaire: 364.42
DISPONIBLE À COMMANDE
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
Synonyms
ARP 100 | SR-01000946390-1 | .beta.-D-Ribofuranose,3,5-tribenzoate | FT-0718436 | ARP-100 | N-2-(Biphenyl-4-Ylsulfonyl)-N-2-(Isopropyloxy)-Acetohydroxamic Acid | MMP-2 Inhibitor III - CAS 704888-90-4 | N~2~-(biphenyl-4-ylsulfonyl)-N-hydroxy-N~2~-(propan-2
Storage
Store at 2-8°C,Desiccated
Shipped In
Wet ice
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Size
Allemagne (EU)
USA*
Price
Qty
5mg
A287330-5mg
—
3 En stock
68,46€
25mg
A287330-25mg
—
1 En stock
288,87€
100mg
A287330-100mg
Sur commande · 8–12 semaines
936,20€
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Moligand™, ≥97% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonymes
ARP 100 | SR-01000946390-1 | .beta.-D-Ribofuranose,3,5-tribenzoate | FT-0718436 | ARP-100 | N-2-(Biphenyl-4-Ylsulfonyl)-N-2-(Isopropyloxy)-Acetohydroxamic Acid | MMP-2 Inhibitor III - CAS 704888-90-4 | N~2~-(biphenyl-4-ylsulfonyl)-N-hydroxy-N~2~-(propan-2
Spécifications et pureté
Moligand™, ≥97%
Mécanismes biochimiques et physiologiques
Selective inhibitor of MMP-2 (IC50= 12 nM); displays selectivity over MMP-9, MMP-3, MMP-1 and MMP-7 (IC50values are 200, 4500, > 50000 and > 50000 nM respectively). Exhibits anti-invasive properties in HT1080 fibrosarcoma cells.
Conditions de stockage de stockage
Store at 2-8°C,Desiccated
Expédié en
Wet ice
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Grade
Moligand™
Type d'action
INHIBITOR
Mécanisme d'action
Inhibitor of MMP2
Pureté
≥97%
Noms et identifiants
Pubchem Sid508810313
Sourires canoniquesCC(C)ON(CC(=O)NO)S(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2
IUPAC NameN-hydroxy-2-[(4-phenylphenyl)sulfonyl-propan-2-yloxyamino]acetamide
InChIKeyPHGLPDURIUEELR-UHFFFAOYSA-N
INCHI1S/C17H20N2O5S/c1-13(2)24-19(12-17(20)18-21)25(22,23)16-10-8-15(9-11-16)14-6-4-3-5-7-14/h3-11,13,21H,12H2,1-2H3,(H,18,20)
Isomères SMILES CC(C)ON(CC(=O)NO)S(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2
Poids moléculaire 364.42
Reaxy-Rn 9930580
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9930580&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClasseBenzene and substituted derivatives
SubclassBiphenyls and derivatives
Intermediate Tree Nodes Not available
Direct ParentBiphenyls and derivatives
Alternative Parents Benzenesulfonamides  Alpha amino acids and derivatives  Benzenesulfonyl compounds  Organosulfonic acids and derivatives  Aminosulfonyl compounds  Hydroxamic acids  N-organohydroxylamines  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Biphenyl - Alpha-amino acid or derivatives - Benzenesulfonamide - Benzenesulfonyl group - Organic sulfonic acid or derivatives - Aminosulfonyl compound - Sulfonyl - Organosulfonic acid or derivatives - Hydroxamic acid - Carboxylic acid derivative - N-organohydroxylamine - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic nitrogen compound - Carbonyl group - Organic oxide - Organic oxygen compound - Organosulfur compound - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as biphenyls and derivatives. These are organic compounds containing to benzene rings linked together by a C-C bond.
External Descriptors Not available
Structure 3D
Modèle de structure chimique interactif





Cibles associées (humaines)
MMP13 Tchem Collagenase 3 (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP9 Tchem Matrix metalloproteinase-9 (5 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP2 Tchem 72 kDa type IV collagenase (6 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP16 Tchem Matrix metalloproteinase-16 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP8 Tchem Neutrophil collagenase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP16 Tchem Matrix metalloproteinase 16 (81 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MMP3 Tchem Matrix metalloproteinase 3 (3433 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MMP8 Tchem Matrix metalloproteinase 8 (1942 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MMP14 Tchem Matrix metalloproteinase 14 (1592 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MMP12 Tchem Matrix metalloproteinase 12 (1130 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MMP7 Tchem Matrix metalloproteinase 7 (1073 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MMP1 Tchem Matrix metalloproteinase-1 (7046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cibles associées (non humaines)
Mmp13 Matrix metalloproteinase 13 (19 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Adam17 ADAM17 (14 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp2 Matrix metalloproteinase-2 (12 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mécanismes d'action
Certificats (CoA, COO, BSE/TSE et tableau d'analyse)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateArticle
B2219192Certificate of AnalysisDec 17, 2024 A287330
B2219193Certificate of AnalysisDec 17, 2024 A287330
B2219194Certificate of AnalysisDec 17, 2024 A287330
Propriétés chimiques et physiques
SolubilitéSolvent:DMSO, Max Conc. mg/mL: 36.44, Max Conc. mM: 100
SensibilitéLight sensitive
Poids moléculaire364.400 g/mol
XLogP32.400
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Exact Mass364.109 Da
Monoisotopic Mass364.109 Da
Topological Polar Surface Area104.000 Ų
Heavy Atom Count25
Formal Charge0
Complexity518.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculateurs de solution
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