CD11b Mouse mAb (Biotin) - Anticorps primaire, specific to CD11b

Cat. No.: Ab191614

GRADE & PURITY ExactAb™, Validated, 0.5 mg/mL

Application

Flow Cytometry

Host species

Souris

Reactive species

Humain

Isotype

Mouse IgG1

Clone Number

ICRF44

Conjugation

Biotin

Vue d’ensemble

Mouse anti Human CD11b Antibody, Monoclonal (ICRF44), could be used for Flow, WB, IHC, IP and so on.

Specifications

Product Name

CD11b Mouse mAb (Biotin) - Anticorps primaire, specific to CD11b

Synonymes

CD11B | antigen CD11b (p170) | CD11 antigen-like family member B | CD11b antigen | Cell surface glycoprotein MAC-1 subunit alpha | Complement component 3 receptor 3 subunit | CR-3 alpha chain | CR3A | CR3AMGC117044 | Integrin alpha M | integrin alpha-M |

Spécifications et pureté

ExactAb™, Validated, 0.5 mg/mL

Mécanismes biochimiques et physiologiques

Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third

Espèce hôte

Souris

Spécificité

CD11b

Immunogène

Rheumatoid synovial cells and human monocytes.

Contrôle positif

Flow: Human peripheral blood monocytes

Conjugation

Biotin

Grade

ExactAb™, Validated

Type de chaîne lumineuse

kappa

Méthode de purification

Protein G purified

Concentration

0.5 mg/mL

Product Line

Produits biologiques

Stockage et expédition

Conditions de stockage de stockage

Store at 2-8°C,Protected from light,Do not freeze

Expédié en

Wet ice,Do not freeze

Stabilité et stockage

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Images

Flow Cytometry: CD11b Mouse mAb (Biotin) (Ab191614)

CD11b Mouse mAb (Biotin) (Ab191614) - Flow Cytometry
Flow cytometry analysis of CD11b expression by human peripheral blood (right panel) compared to an isotype control (left panel). Cells were stained with CD11b Mouse mAb (Biotin) (Ab191614) at 0.1μg/test for 1 hour at 4°C. Then incubated with Recombinant Streptavidin Protein (R-PE) (rp156150) at 0.1μg/test for 30 minutes at 4°C in the dark. Left panel - Mouse IgG (Biotin) (Ab180306).

Flow Cytometry: CD11b Mouse mAb (Biotin) (Ab191614)

CD11b Mouse mAb (Biotin) (Ab191614) - Flow Cytometry
Flow cytometry analysis of CD11b expression by human peripheral blood monocytes (red) compared to an isotype control (blue). Cells were stained with CD11b Mouse mAb (Biotin) (Ab191614) at 0.1μg/test for 1 hour at 4°C. Blue - Mouse IgG (Biotin) (Ab180306). Then incubated with Recombinant Streptavidin Protein (R-PE) (rp156150) at 0.1μg/test for 30 minutes at 4°C in the dark. Black - Unlabelled control, cells without incubation with primary antibody.

Application

Application

Dilution info

Flow Cytometry

≤0.3 μg/test, the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume

Cibles associées (humaines)

ITGAM Tbio Integrin alpha-M (0 Activities)

Discover Target: ITGAM

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mécanismes d'action