Peptides

Marine natural products (MNPs) are bioactive metabolites produced by marine microorganisms, algae, invertebrates, and other marine organisms. They are characterized by novel molecular scaffolds, complex stereochemical structures, a high abundance of halogenated compounds, and diverse biological ...

Amide bonds, peptide bonds, and ester bonds are widely present in drug molecules, peptides, natural products, fine chemicals, and functional materials. For synthetic chemists, the key question in these reactions is usually not simply “whether the target bond can be formed,” but whether the ...

Peptides have become an important class of molecules in modern medicinal chemistry and chemical biology. Compared with traditional small molecules, peptides often offer higher target selectivity and stronger molecular recognition capability, while still retaining good structural tunability. As a ...

Applications of Peptides

Screening and Optimization of Peptides

A peptide can be biotinylated yet still read negative in a biotin assay. The most common root cause is steric hindrance or conformational occlusion: the biotin is positioned too close to the peptide backbone or becomes shielded by the peptide’s structure/aggregation, so streptavidin/avidin ...

Peptides are the fundamental structural units of proteins, consisting of specific sequences of amino acids linked by peptide bonds. Peptides composed of two amino acids are called dipeptides, those of three amino acids are called tripeptides, and so on. In cosmetics, commonly used peptides are ...

Selection of Appropriate Peptide Purity

L-Tyrosine is a crucial non-essential amino acid widely used in cell culture and various laboratory research applications. As a fundamental component of protein synthesis, L-Tyrosine not only participates in the synthesis of various biomolecules but also plays a vital role in cell development ...

Somatostatin is an important regulatory peptide, widely distributed in the central nervous system, endocrine glands, and gastrointestinal tract.

In peptide synthesis, Boc protection groups are widely used to protect the amino terminus of amino acids to prevent unnecessary reactions during synthesis. After the peptide synthesis is complete, the peptide is released from the resin through the cleavage and deprotection steps, and these ...

Solid-phase peptide synthesis (SPPS) is a revolutionary biochemical technique that has become the primary method for synthesizing peptides and proteins since its introduction in the 1960s. Robert Bruce Merrifield first proposed the concept of SPPS in 1963, and this groundbreaking work not only ...

With the increasing global issue of bacterial resistance and the frequent emergence of new infectious diseases, ribosomally synthesized antimicrobial peptides (RAMPs) have become a promising focus in antibiotic research. Antimicrobial peptides can be categorized into non-ribosomal peptides and ...