KLHL2 Mouse mAb - Anticorps primaire, specific to KLHL2

Cat. No.: Ab112273

GRADE & PURITY See COA

Application

Flow Cytometry, IF/ICC, WB

Host species

Souris

Reactive species

conseil, Humain, Souris

Isotype

Mouse IgG2b

Clone Number

OTI6D8

Conjugation

Unconjugated

Vue d’ensemble

Mouse anti Human KLHL2 Antibody, Monoclonal (OTI6D8), could be used for WB, IF/ICC, Flow Cytometry and so on.

Specifications

Product Name

KLHL2 Mouse mAb - Anticorps primaire, specific to KLHL2

Synonymes

ABP KELCHantibody | Actin binding protein Mayvenantibody | Actin-binding protein Mayven antibody | kelch antibody | kelch like 2 antibody | Kelch like 2 | Kelch like family member 2 antibody | Kelch like protein 2 antibody | Kelch-like protein 2 antibody

Spécifications et pureté

See COA

Mécanismes biochimiques et physiologiques

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, WNK1, WNK3 and WNK4, leading most often to their proteasomal degradation (PubMed:23838290). The BCR(KLHL2)

Espèce hôte

Souris

Spécificité

KLHL2

Immunogène

Recombinant protein of human KLHL2 (AA 1-100 & 494-593) produced in HEK293T cell.

Contrôle positif

WB: HEK293T transfected with pCMV6-ENTRY KLHL2 cDNA for 48 hrs; Jurkat lysates. IF/ICC: COS7 cells transiently transfected with pCMV6-ENTRY KLHL2. Flow Cytometry: HEK293T cells transfected with pCMV6-ENTRY KLHL2.

Conjugation

Unconjugated

SDS-PAGE

150 kDa

Méthode de purification

Protein A purified

Concentration

See COA

Stockage et expédition

Forme

Liquid

Conditions de stockage de stockage

Store at -20°C,Avoid repeated freezing and thawing

Expédié en

Ice chest + Ice pads

Stabilité et stockage

Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Application

• Application: Dilution info
• WB:

  1/500-1/2000 ;

• Flow Cytometry:

  1/100;

• IF/ICC:

  1:100 ;

Cibles associées (humaines)

KLHL2 Tbio Kelch-like protein 2 (0 Activities)

Discover Target: KLHL2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Foire aux questions

How should this product be stored?

Store at ?20 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (KLHL2 Mouse mAb); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.