FAP

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  1. SP-13786
    CAS: 1448440-52-5 PubChem CID: 71621488 Formule: C17H14F2N4O2 Poids moléculaire: 344.32
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: S174266
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    Nom IUPAC
    N-[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]quinoline-4-carboxamide
    SMILES
    C1C(N(CC1(F)F)C(=O)CNC(=O)C2=CC=NC3=CC=CC=C23)C#N
    InChIKey
    PUOOCZVRHBHJRS-NSHDSACASA-N
    InChI
    1S/C17H14F2N4O2/c18-17(19)7-11(8-20)23(10-17)15(24)9-22-16(25)13-5-6-21-14-4-2-1-3-12(13)14/h1-6,11H,7,9-10H2,(H,22,25)/t11-/m0/s1
    Synonymes
    AKOS027423971 | EX-A2803 | N-[2-[(2S)-2-Cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-4-quinolinecarboxamide | ZB149...
  2. WAY-323975
    CAS: 510716-65-1 PubChem CID: 1073012 Formule: C16H22ClN3O5S Poids moléculaire: 403.88
    10mM in DMSO
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: W424395
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    Nom IUPAC
    ethyl 4-[2-[(4-chlorophenyl)sulfonyl-methylamino]acetyl]piperazine-1-carboxylate
    SMILES
    CCOC(=O)N1CCN(CC1)C(=O)CN(C)S(=O)(=O)C2=CC=C(C=C2)Cl
    InChIKey
    GVRRKYYMISVYGI-UHFFFAOYSA-N
    InChI
    1S/C16H22ClN3O5S/c1-3-25-16(22)20-10-8-19(9-11-20)15(21)12-18(2)26(23,24)14-6-4-13(17)5-7-14/h4-7H,3,8-12H2,1-2H3
  3. WAY-323975
    CAS: 510716-65-1 PubChem CID: 1073012 Formule: C16H22ClN3O5S Poids moléculaire: 403.88
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: W416981
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    Nom IUPAC
    ethyl 4-[2-[(4-chlorophenyl)sulfonyl-methylamino]acetyl]piperazine-1-carboxylate
    SMILES
    CCOC(=O)N1CCN(CC1)C(=O)CN(C)S(=O)(=O)C2=CC=C(C=C2)Cl
    InChIKey
    GVRRKYYMISVYGI-UHFFFAOYSA-N
    InChI
    1S/C16H22ClN3O5S/c1-3-25-16(22)20-10-8-19(9-11-20)15(21)12-18(2)26(23,24)14-6-4-13(17)5-7-14/h4-7H,3,8-12H2,1-2H3
  4. FAPI-34
    CAS: 2374782-07-5 Formule: C50H57F2N13O18 Poids moléculaire: 1166.06
    ◐ .Sur commande · 8–12 semaines Article #: F647693
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    SMILES
    O=C(C1=CC=NC(C=C2)=C1C=C2OCCCN(CC3)CCN3C(CN(CC4=NC=CN4CC(N[C@H](C(O)=O)CC(C(O)=O)C(O)=O)=O)CC5=NC=CN5CC(N[C@H](C(O)=O)CC(C(O)=O)C(O)=O)=O)=O)NCC(N(CC6show more
  5. FAPI-4 TFA salt
    CAS: 2374782-02-0(free base) Formule: C40H54F2N10O10(free base) Poids moléculaire: 872.91(free base)
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Sur commande · 8–12 semaines Article #: F648286
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    Nom IUPAC
    2-[4,7-bis(carboxymethyl)-10-[2-[4-[3-[4-[[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]carbamoyl]quinolin-6-yl]oxypropyl]piperazin-1-yl]-2show more
    SMILES
    C1CN(CCN1CCCOC2=CC3=C(C=CN=C3C=C2)C(=O)NCC(=O)N4CC(CC4C#N)(F)F)C(=O)CN5CCN(CCN(CCN(CC5)CC(=O)O)CC(=O)O)CC(=O)O
    InChIKey
    ICWDAESAANBIGG-LJAQVGFWSA-N
    InChI
    1S/C40H54F2N10O10/c41-40(42)21-29(22-43)52(28-40)34(53)23-45-39(61)31-4-5-44-33-3-2-30(20-32(31)33)62-19-1-6-46-15-17-51(18-16-46)35(54)24-47-7-9-48(2show more
    Synonymes
    MS-31619 | FAPI-04 | FAPI-4 | ICWDAESAANBIGG-LJAQVGFWSA-N | AT39479 | DOTA-fapi-04 | EX-A5967 | 2-[4,7-bis(carboxymet...
  6. Suc-Gly-Pro-AMC
    CAS: 80049-85-0 PubChem CID: 21121742 Formule: C21H23N3O7 Poids moléculaire: 429.42
    ◐ .Sur commande · 8–12 semaines Article #: S648136
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    Nom IUPAC
    4-[[2-[(2S)-2-[(4-methyl-2-oxochromen-7-yl)carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-4-oxobutanoic acid
    SMILES
    CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C3CCCN3C(=O)CNC(=O)CCC(=O)O
    InChIKey
    NKEPCOOQNLGSLJ-HNNXBMFYSA-N
    InChI
    1S/C21H23N3O7/c1-12-9-20(29)31-16-10-13(4-5-14(12)16)23-21(30)15-3-2-8-24(15)18(26)11-22-17(25)6-7-19(27)28/h4-5,9-10,15H,2-3,6-8,11H2,1H3,(H,22,25)(Hshow more
    Synonymes
    4-[[2-[(2S)-2-[(4-methyl-2-oxochromen-7-yl)carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-4-oxobutanoic acid | HY-14598...
  7. Ac-Gly-BoroPro
    CAS: 886992-99-0 PubChem CID: 102176419 Formule: C8H15BN2O4 Poids moléculaire: 214.03
    ◐ .Sur commande · 8–12 semaines Article #: A650587
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    Nom IUPAC
    [(2S)-1-(2-acetamidoacetyl)pyrrolidin-2-yl]boronic acid
    SMILES
    B(C1CCCN1C(=O)CNC(=O)C)(O)O
    InChIKey
    UUOZISWTWURDGU-SSDOTTSWSA-N
    InChI
    1S/C8H15BN2O4/c1-6(12)10-5-8(13)11-4-2-3-7(11)9(14)15/h7,14-15H,2-5H2,1H3,(H,10,12)/t7-/m1/s1
  8. OncoFAP
    CAS: 2639365-69-6 Formule: C21H19F2N5O5 Poids moléculaire: 459.40
    ◐ .Sur commande · 8–12 semaines Article #: O651308
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    SMILES
    OC(CCC(NC1=CC=CC2=C1N=CC=C2C(NCC(N3[C@@H](CC(F)(C3)F)C#N)=O)=O)=O)=O
  9. FAP-2286
    CAS: 2581741-18-4 Formule: C67H99N13O18S3 Poids moléculaire: 1470.77
    ◐ .Sur commande · 8–12 semaines Article #: F646366
    Voir le produit
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    SMILES
    O=C(N1[C@@](C(N[C@@](C(N[C@H](C(N[C@H](C2=O)CC3=CC=CC=C3)=O)CCC(N)=O)=O)([H])[C@H](O)C)=O)([H])CCC1)[C@@](CCC4)([H])N4C([C@H](CSCC5=CC(CSCCNC(CN(CCN(Cshow more
  10. FAPI-46
    CAS: 2374782-04-2 PubChem CID: 139400499 Formule: C41H57F2N11O9 Poids moléculaire: 885.96
    ◐ .Sur commande · 8–12 semaines Article #: F650690
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    Nom IUPAC
    2-[4,7-bis(carboxymethyl)-10-[2-[4-[3-[[4-[[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]carbamoyl]quinolin-6-yl]-methylamino]propyl]piperashow more
    SMILES
    CN(CCCN1CCN(CC1)C(=O)CN2CCN(CCN(CCN(CC2)CC(=O)O)CC(=O)O)CC(=O)O)C3=CC4=C(C=CN=C4C=C3)C(=O)NCC(=O)N5CC(CC5C#N)(F)F
    InChIKey
    SDBGUEFOSXNKBX-HKBQPEDESA-N
    InChI
    1S/C41H57F2N11O9/c1-47(30-3-4-34-33(21-30)32(5-6-45-34)40(63)46-24-35(55)54-29-41(42,43)22-31(54)23-44)7-2-8-48-17-19-53(20-18-48)36(56)25-49-9-11-50(show more
    Synonymes
    2374782-04-2 | 59QC5DY68A | AKOS040757603 | FAPI-46 | SCHEMBL21257093 | MS-31645 | EX-A5968 | [10-[2-[4-[3-[[4-[[[2-[...
  11. Sibrotuzumab (anti-FAP), BINDING AGENT of Fibroblast activation protein alpha binding agent
    CAS: 216669-97-5
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: Ab183093
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    Associated targets
    FAP
    Short Overview
    Purity≥95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Espèces réactives
    Humain
    Isotype
    Human IgG1
    Espèce hôte
    Humain
    Conjugation
    Unconjugated
    SMILES
    [Sibrotuzumab]
    Synonymes
    170 kDa melanoma membrane-bound gelatinase antibody | Dipeptidyl peptidase FAP antibody | DPPIV antibody | FAP antibo...
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Foire aux questions

How is the FAP listing put together?
It draws on reported FAP annotations within Immunology/Inflammation and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a FAP modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the FAP entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for FAP compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For FAP work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the FAP compound I need is not listed?
Search by CAS number or SMILES first, since analogs of FAP compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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