Ingenol 3,20-dibenzoate - Moligand™, 10 mM in DMSO , CAS No.59086-90-7

CAS: 59086-90-7 Cat. No.: I1496568 Molecular Weight: 556.65 EC Number: 637-387-6

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Ingenol 3,20-dibenzoate is a potent protein kinase C ( PKC ) isoform-selective agonist. Ingenol 3,20-dibenzoate induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the particulate fraction and induces morphologically typical apoptosis through de novo synthesis of macromolecules. Ingenol 3,20-dibenzoate increases the IFN-γ production and degranulation by NK cells, especially when NK cells are stimulated by NSCLC cells .

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Product Properties

• Ki Data: Binding to PKCα: Ki= 240 nM

Names and Identifiers

• Isomeric SMILES: C[C@@H]1C[C@@H]2[C@@H](C2(C)C)[C@@H]3C=C([C@H]([C@@]4(C1(C3=O)C=C([C@@H]4OC(=O)C5=CC=CC=C5)C)O)O)COC(=O)C6=CC=CC=C6
• WGK Germany: 3
• Molecular Weight: 556.65
• Reaxy-Rn: 25557798
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25557798&ln=

Chemical and Physical Properties

• Refractive Index: n20D1.64 (Predicted)
• Boil Point(°C): ~697.0° C at 760 mmHg (Predicted)
• Melt Point(°C): 20-23° C