Antifolato
109 prodotti
Prodotti
- Pirimetamina, Dihydrofolate reductase inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: P141438Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
- SMILES
- CCC1=C(C(=NC(=N1)N)N)C2=CC=C(C=C2)Cl
- InChIKey
- WKSAUQYGYAYLPV-UHFFFAOYSA-N
- InChI
- 1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)
- Sinonimi
- NCI-C01683 | Z3614QOX8W | CRL-8142 & Pyrimethamine | SMR000058714 | CPD000058714 | DTXCID601217 | Pyrimethamine (USP:...
- PirimetaminaAnalytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: P114361Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
- SMILES
- CCC1=C(C(=NC(=N1)N)N)C2=CC=C(C=C2)Cl
- InChIKey
- WKSAUQYGYAYLPV-UHFFFAOYSA-N
- InChI
- 1S/C12H13ClN4/c1-2-9-10(11(14)17-12(15)16-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H4,14,15,16,17)
- Sinonimi
- NCI-C01683 | Z3614QOX8W | CRL-8142 & Pyrimethamine | SMR000058714 | CPD000058714 | DTXCID601217 | Pyrimethamine (USP:...
- Trimethoprim lactate salt● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: T168839Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 2-hydroxypropanoic acid;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
- SMILES
- CC(C(=O)O)O.COC1=CC(=CC(=C1OC)OC)CC2=CN=C(N=C2N)N
- InChIKey
- IIZVTUWSIKTFKO-UHFFFAOYSA-N
- InChI
- 1S/C14H18N4O3.C3H6O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15;1-2(4)3(5)6/h5-7H,4H2,1-3H3,(H4,15,16,17,18);2,4H,1H3,(H,5,6)
- Sinonimi
- SCHEMBL950634 | FT-0630496 | 2-oxidanylpropanoic acid; 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine | J-0...
- DiaveridineAnalytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: D135965Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 5-[(3,4-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine
- SMILES
- COC1=C(C=C(C=C1)CC2=CN=C(N=C2N)N)OC
- InChIKey
- LDBTVAXGKYIFHO-UHFFFAOYSA-N
- InChI
- 1S/C13H16N4O2/c1-18-10-4-3-8(6-11(10)19-2)5-9-7-16-13(15)17-12(9)14/h3-4,6-7H,5H2,1-2H3,(H4,14,15,16,17)
- Sinonimi
- CCG-213021 | 2, 5-[(3,4-dimethoxyphenyl)methyl]- | Diaveridina | EN300-7440332 | 5-[(3,4-dimethoxyphenyl)methyl]pyrim...
- Trimethoprim-d3◐ .Su ordinazione · 8–12 settimane Oggetto #: T334367Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 5-[[3,5-dimethoxy-4-(trideuteriomethoxy)phenyl]methyl]pyrimidine-2,4-diamine
- SMILES
- COC1=CC(CC2=CN=C(N)N=C2N)=CC(OC)=C1OC([2H])([2H])[2H]
- InChIKey
- IEDVJHCEMCRBQM-HPRDVNIFSA-N
- InChI
- 1S/C14H18N4O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18)/i3D3
- Sinonimi
- 5-({3,5-Dimethoxy-4-[(~2~H_3_)methyloxy]phenyl}methyl)pyrimidine-2,4-diamine | 5-[[3,5-dimethoxy-4-(trideuteriomethox...
- Methotrexate disodium salt, Dihydrofolate reductase inhibitorSolido Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: M338754Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- disodium;(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioate
- SMILES
- CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Na+].[Na+]
- InChIKey
- DASQOOZCTWOQPA-GXKRWWSZSA-L
- InChI
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- Sinonimi
- Methotrexate, Sodium Salt | DTXCID1017123 | MS-20174 | Disodium methotrexate | DS-3425 | 3,6-Endomethylenephthalic an...
- Aminopterin10mM in DMSO● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: A424654Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
- SMILES
- Nc1nc(N)c2nc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2n1
- InChIKey
- TVZGACDUOSZQKY-LBPRGKRZSA-N
- InChI
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- Sinonimi
- aminopterin|4-Aminofolic acid|54-62-6|4-Amino-PGA|APGA|Aminopteridine|Aminotrexate|Aminopterine|4-Aminopteroylglutami...
- Calcium Levofolinate10mM in Water● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: C426083Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- calcium;(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate
- SMILES
- C1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Ca+2]
- InChIKey
- KVUAALJSMIVURS-QNTKWALQSA-L
- InChI
- show more
- Sinonimi
- Calcium levofolinate (INN) | MFCD08704249 | L-Glutamic acid, N-(4-(((2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-p...
- Calcium LevofolinateSolido ≥99%● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: C129891Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- calcium;(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate
- SMILES
- C1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Ca+2]
- InChIKey
- KVUAALJSMIVURS-QNTKWALQSA-L
- InChI
- show more
- Sinonimi
- Calcium levofolinate (INN) | MFCD08704249 | L-Glutamic acid, N-(4-(((2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-p...
- Diaveridine10mM in DMSO● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: D424576Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 5-[(3,4-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine
- SMILES
- COC1=C(C=C(C=C1)CC2=CN=C(N=C2N)N)OC
- InChIKey
- LDBTVAXGKYIFHO-UHFFFAOYSA-N
- InChI
- 1S/C13H16N4O2/c1-18-10-4-3-8(6-11(10)19-2)5-9-7-16-13(15)17-12(9)14/h3-4,6-7H,5H2,1-2H3,(H4,14,15,16,17)
- Sinonimi
- CCG-213021 | 2, 5-[(3,4-dimethoxyphenyl)methyl]- | Diaveridina | EN300-7440332 | 5-[(3,4-dimethoxyphenyl)methyl]pyrim...
- Folinic acidCAS: 6035-45-6 Formula: C20H21CaN7O7.5H2O Peso molecolare: 601.5910mM in Water● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: F425013Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- calcium;(2S)-2-[[4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioate;pentahydrate
- SMILES
- C1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].O.O.O.O.O.[Ca+2]
- InChIKey
- NPPBLUASYYNAIG-ZIGBGYJWSA-L
- InChI
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- Sinonimi
- CALCII FOLINAS [WHO-IP LATIN] | 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-, (+)-, (Z)-2-b...
- Folinic acid calcium salt hydrateCAS: 1492-18-8 Formula: C20H21CaN7O7 · xH2O Peso molecolare: 511.50 (anhydrous basis)10mM in Water● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: F421750Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- calcium;(2S)-2-[[4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioate
- SMILES
- [Ca++].[H]O[H].[H]C(=O)N1C(CNc2ccc(cc2)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)CNc3nc(N)nc(O)c13
- InChIKey
- KVUAALJSMIVURS-ZEDZUCNESA-L
- InChI
- show more
- Sinonimi
- calcium folinate|LEUCOVORIN CALCIUM|1492-18-8|Wellcovorin|Folinic acid calcium salt|Calcium leucovorin|Lederfoline|Re...
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Domande frequenti
How is the Antifolate listing put together?
It draws on reported Antifolate annotations within Cell Cycle/DNA Damage and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an Antifolate modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Antifolate entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Antifolate compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Antifolate work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Antifolate compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Antifolate compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.