Ricombinasi inducibile 1
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57 prodotti
Prodotti popolari
- 6-Bromo-2-hydroxy-3-methoxybenzaldehyde● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: B153189Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 6-bromo-2-hydroxy-3-methoxybenzaldehyde
- SMILES
- COC1=C(C(=C(C=C1)Br)C=O)O
- InChIKey
- JUPJZUTYDWXZAQ-UHFFFAOYSA-N
- InChI
- 1S/C8H7BrO3/c1-12-7-3-2-6(9)5(4-10)8(7)11/h2-4,11H,1H3
- Sinonimi
- EN300-6498200 | J-012961 | SCHEMBL424251 | 6-Bromo-2-hydroxy-3-methoxybenzaldehyde, 98% | FT-0637938 | J-510172 | DS-...
- APY 29CAS: 1216665-49-4 Formula: C17H16N8 Peso molecolare: 332.36● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: A288548Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 2-N-(3H-benzimidazol-5-yl)-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
- SMILES
- C1CC1C2=CC(=NN2)NC3=NC(=NC=C3)NC4=CC5=C(C=C4)N=CN5
- InChIKey
- WJNBSTLIALIIEW-UHFFFAOYSA-N
- InChI
- 1S/C17H16N8/c1-2-10(1)13-8-16(25-24-13)22-15-5-6-18-17(23-15)21-11-3-4-12-14(7-11)20-9-19-12/h3-10H,1-2H2,(H,19,20)(H3,18,21,22,23,24,25)
- Sinonimi
- (E)-N-(6-((5-cyclopropyl-1H-pyrazol-3-yl)imino)-1,6-dihydropyrimidin-2-yl)-1H-benzo[d]imidazol-6-amine | N2-1H-Benzim...
- Diphenylcyclopropenone(DPC)Solido Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: A115107Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 2,3-diphenylcycloprop-2-en-1-one
- SMILES
- C1=CC=C(C=C1)C2=C(C2=O)C3=CC=CC=C3
- InChIKey
- HCIBTBXNLVOFER-UHFFFAOYSA-N
- InChI
- 1S/C15H10O/c16-15-13(11-7-3-1-4-8-11)14(15)12-9-5-2-6-10-12/h1-10H
- Sinonimi
- DPC | Cyclopropenone, 2,3-diphenyl- | NCGC00166113-01 | SR-01000644630-1 | AMY1261 | DIPHENCYPRONE [MI] | DIPHENYLCYC...
- B I09CAS: 1607803-67-7 Formula: C16H17NO5 Peso molecolare: 303.31◐ .Su ordinazione · 8–12 settimane Oggetto #: B287381Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 7-(1,3-dioxan-2-yl)-8-hydroxy-1,2,3,4-tetrahydrochromeno[3,4-c]pyridin-5-one
- SMILES
- C1COC(OC1)C2=C(C=CC3=C2OC(=O)C4=C3CCNC4)O
- InChIKey
- UYYMWNUDIOPESF-UHFFFAOYSA-N
- InChI
- 1S/C16H17NO5/c18-12-3-2-10-9-4-5-17-8-11(9)15(19)22-14(10)13(12)16-20-6-1-7-21-16/h2-3,16-18H,1,4-8H2
- Sinonimi
- 7-(1,3-Dioxan-2-yl)-1,2,3,4-tetrahydro-8-hydroxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one
- Sunitinib Malate, Tyrosine-protein kinase receptor RET inhibitor● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: E129728Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide;(2S)-2-hydroxybutanedioic acid
- SMILES
- CCN(CC)CCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)F)NC2=O)C.C(C(C(=O)O)O)C(=O)O
- InChIKey
- LBWFXVZLPYTWQI-IPOVEDGCSA-N
- InChI
- show more
- Sinonimi
- 1H-Pyrrole-3-carboxamide, N-(2-(diethylamino)ethyl)-5-((Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4...
- Sunitinib, Inhibitor of fibroblast growth factor receptor 1;Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of fms related receptor tyrosine kinase 4;Inhibitor of kinase insert domain receptor;Inhibitor of KIT proto-oncogene; receptor tyrosine kinase;ICAS: 557795-19-4 Numero EC: 111-194-2 PubChem CID: 5329102 Formula: C22H27FN4O2 Peso molecolare: 398.47Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: S126061Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
- SMILES
- CCN(CC)CCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)F)NC2=O)C
- InChIKey
- WINHZLLDWRZWRT-ATVHPVEESA-N
- InChI
- show more
- Sinonimi
- 1H-Pyrrole-3-carboxamide,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl- | D08552 | C22H27FN4O2 | N-(2-(Diet...
- Toyocamycin● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: T275971Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 4-amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile
- SMILES
- C1=C(C2=C(N=CN=C2N1C3C(C(C(O3)CO)O)O)N)C#N
- InChIKey
- XOKJUSAYZUAMGJ-WOUKDFQISA-N
- InChI
- 1S/C12H13N5O4/c13-1-5-2-17(11-7(5)10(14)15-4-16-11)12-9(20)8(19)6(3-18)21-12/h2,4,6,8-9,12,18-20H,3H2,(H2,14,15,16)/t6-,8-,9-,12-/m1/s1
- Sinonimi
- L7995C4D7F | 4-Amino-7-.beta.-D-ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-5-carbonitrile | NSC-99843 | Antibiotic E21...
- 4μ8C● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: C167186Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 7-hydroxy-4-methyl-2-oxochromene-8-carbaldehyde
- SMILES
- CC1=CC(=O)OC2=C1C=CC(=C2C=O)O
- InChIKey
- RTHHSXOVIJWFQP-UHFFFAOYSA-N
- InChI
- 1S/C11H8O4/c1-6-4-10(14)15-11-7(6)2-3-9(13)8(11)5-12/h2-5,13H,1H3
- Sinonimi
- IRE1 Inhibitor III | BB 0256929 | HMS3653K06 | 4?8C | F2158-2222 | 8-formyl-7-hydroxy-4-methylcoumarin | IRE1 Inhibit...
- 4μ8C10mM in DMSO● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: C421493Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 7-hydroxy-4-methyl-2-oxochromene-8-carbaldehyde
- SMILES
- CC1=CC(=O)OC2=C1C=CC(=C2C=O)O
- InChIKey
- RTHHSXOVIJWFQP-UHFFFAOYSA-N
- InChI
- 1S/C11H8O4/c1-6-4-10(14)15-11-7(6)2-3-9(13)8(11)5-12/h2-5,13H,1H3
- Sinonimi
- BB 0256929 | HMS3653K06 | 4?8C | F2158-2222 | 8-formyl-7-hydroxy-4-methylcoumarin | IRE1 Inhibitor III | J-007348 | S...
- 6-Bromo-2-hydroxy-3-methoxybenzaldehyde10mM in DMSO● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: B422438Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 6-bromo-2-hydroxy-3-methoxybenzaldehyde
- SMILES
- COC1=C(C(=C(C=C1)Br)C=O)O
- InChIKey
- JUPJZUTYDWXZAQ-UHFFFAOYSA-N
- InChI
- 1S/C8H7BrO3/c1-12-7-3-2-6(9)5(4-10)8(7)11/h2-4,11H,1H3
- Sinonimi
- EN300-6498200 | J-012961 | SCHEMBL424251 | 6-Bromo-2-hydroxy-3-methoxybenzaldehyde, 98% | FT-0637938 | J-510172 | DS-...
- AMG 18 hydrochloride● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: A288841Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 2-chloro-N-[6-methyl-5-[3-[2-[[(3S)-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxynaphthalen-1-yl]benzenesulfonamide;hydrochloride
- SMILES
- CC1=C(C2=C(C=C1)C(=CC=C2)NS(=O)(=O)C3=CC=CC=C3Cl)OC4=C(C=CC=N4)C5=NC(=NC=C5)NC6CCCNC6.Cl
- InChIKey
- CNWIPRHGMZTPSB-BOXHHOBZSA-N
- InChI
- show more
- Sinonimi
- 2-Chloro-N-[6-methyl-5-[[3-[2-[(3S)-3-piperidinylamino]-4-pyrimidinyl]-2-pyridinyl]oxy]-1-naphthalenyl]benzenesulfona...
- APY 29CAS: 1216665-49-4 Formula: C17H16N8 Peso molecolare: 332.3610mM in DMSO● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: A420934Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 2-N-(3H-benzimidazol-5-yl)-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
- SMILES
- C1CC1C2=CC(=NN2)NC3=NC(=NC=C3)NC4=CC5=C(C=C4)N=CN5
- InChIKey
- WJNBSTLIALIIEW-UHFFFAOYSA-N
- InChI
- 1S/C17H16N8/c1-2-10(1)13-8-16(25-24-13)22-15-5-6-18-17(23-15)21-11-3-4-12-14(7-11)20-9-19-12/h3-10H,1-2H2,(H,19,20)(H3,18,21,22,23,24,25)
- Sinonimi
- (E)-N-(6-((5-cyclopropyl-1H-pyrazol-3-yl)imino)-1,6-dihydropyrimidin-2-yl)-1H-benzo[d]imidazol-6-amine;N2-1H-Benzimid...
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Domande frequenti
How is the IRE1 listing put together?
It draws on reported IRE1 annotations within Cell Cycle/DNA Damage and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an IRE1 modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the IRE1 entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for IRE1 compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For IRE1 work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the IRE1 compound I need is not listed?
Search by CAS number or SMILES first, since analogs of IRE1 compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.