ROCK
155 prodotti
Prodotti
- GSK 269962, Inhibitor of Rho associated coiled-coil containing protein kinase 1;Inhibitor of Rho associated coiled-coil containing protein kinase 2CAS: 850664-21-0 Formula: C29H30N8O5 Peso molecolare: 570.6Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: G287476Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- N-[3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-6-yl]oxyphenyl]-4-(2-morpholin-4-ylethoxy)benzamide
- SMILES
- CCN1C2=CC(=NC=C2N=C1C3=NON=C3N)OC4=CC=CC(=C4)NC(=O)C5=CC=C(C=C5)OCCN6CCOCC6
- InChIKey
- YOVNFNXUCOWYSG-UHFFFAOYSA-N
- InChI
- show more
- Sinonimi
- GTPL8037 | NSC-767348 | SCHEMBL1838346 | UNII-F89KMM7TE2 | N-(3-((2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo...
- NarciclasinaCAS: 29477-83-6 Formula: C14H13NO7 Peso molecolare: 307.26● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: N125921Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- (2S,3R,4S,4aR)-2,3,4,7-tetrahydroxy-3,4,4a,5-tetrahydro-2H-[1,3]dioxolo[4,5-j]phenanthridin-6-one
- SMILES
- C1OC2=C(O1)C(=C3C(=C2)C4=CC(C(C(C4NC3=O)O)O)O)O
- InChIKey
- LZAZURSABQIKGB-AEKGRLRDSA-N
- InChI
- 1S/C14H13NO7/c16-6-1-5-4-2-7-13(22-3-21-7)11(18)8(4)14(20)15-9(5)12(19)10(6)17/h1-2,6,9-10,12,16-19H,3H2,(H,15,20)/t6-,9+,10+,12-/m0/s1
- Sinonimi
- Lycoricidin-A | MFCD01729949 | [1,3]Dioxolo[4,5-j]phenanthridin-6(2H)-one, 3,4,4a,5-tetrahydro-2,3,4,7-tetrahydroxy-,...
- GSK429286A, Inhibitor of Rho associated coiled-coil containing protein kinase 1;Inhibitor of ribosomal protein S6 kinase A1Solido Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: G127028Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- N-(6-fluoro-1H-indazol-5-yl)-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-pyridine-5-carboxamide
- SMILES
- CC1=C(C(CC(=O)N1)C2=CC=C(C=C2)C(F)(F)F)C(=O)NC3=C(C=C4C(=C3)C=NN4)F
- InChIKey
- OLIIUAHHAZEXEX-UHFFFAOYSA-N
- InChI
- show more
- Sinonimi
- HMS3244C08 | HMS3654N12 | N6-ethanimidoyl-L-lysine dihydrochloride | dihydropyridone indazole amide 15 | HY-11000 | N...
- OXA 06 dihydrochloride● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: O288636Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- N-[(2-fluorophenyl)methyl]-1-[4-(1H-pyrrolo[2,3-b]pyridin-4-yl)phenyl]methanamine;dihydrochloride
- SMILES
- C1=CC=C(C(=C1)CNCC2=CC=C(C=C2)C3=C4C=CNC4=NC=C3)F.Cl.Cl
- InChIKey
- ZRBCUSMZOWMVJS-UHFFFAOYSA-N
- InChI
- 1S/C21H18FN3.2ClH/c22-20-4-2-1-3-17(20)14-23-13-15-5-7-16(8-6-15)18-9-11-24-21-19(18)10-12-25-21;;/h1-12,23H,13-14H2,(H,24,25);2*1H
- Sinonimi
- 2-Fluoro-N-[[4-(1H-pyrrolo[2,3-b]pyridin-4-yl)phenyl]methyl]benzenemethanamine dihydrochloride
- 5-(Piperazin-1-ylsulfonyl)isoquinoline● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: H275141Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 5-piperazin-1-ylsulfonylisoquinoline
- SMILES
- C1CN(CCN1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3
- InChIKey
- UPTYCYWTFGTCCG-UHFFFAOYSA-N
- InChI
- 1S/C13H15N3O2S/c17-19(18,16-8-6-14-7-9-16)13-3-1-2-11-10-15-5-4-12(11)13/h1-5,10,14H,6-9H2
- Sinonimi
- 1-(5-Isoquinolinesulfonyl)piperazine | Piperazine, 1-(5-isoquinolinylsulfonyl)- | BDBM15203 | MFCD00209852 | NCGC0002...
- Valeric acidLiquido Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(GC)● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: V108272Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- pentanoic acid
- SMILES
- CCCCC(=O)O
- InChIKey
- NQPDZGIKBAWPEJ-UHFFFAOYSA-N
- InChI
- 1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)
- Sinonimi
- n-Valeric acid | Pentanoic Acid
- Valeric acidMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. CP ? Chemically Pure grade — moderate purity above technical grade but below analytical. Use for general lab reactions where ultra-low impurities aren't critical. ≥98%● In magazzino — Germania Oggetto #: V108270Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- pentanoic acid
- SMILES
- CCCCC(=O)O
- InChIKey
- NQPDZGIKBAWPEJ-UHFFFAOYSA-N
- InChI
- 1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)
- Sinonimi
- Kyselina valerova | CHEBI:17418 | FT-0694066 | Valeric acid ( Pentanoic acid ) | VALPROIC ACID IMPURITY A [EP IMPURIT...
- AS 1892802CAS: 928320-12-1 Formula: C20H19N3O2 Peso molecolare: 333.38● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: A288609Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 1-[(1S)-2-hydroxy-1-phenylethyl]-3-(4-pyridin-4-ylphenyl)urea
- SMILES
- C1=CC=C(C=C1)C(CO)NC(=O)NC2=CC=C(C=C2)C3=CC=NC=C3
- InChIKey
- WDTFYYZHMRBVHK-LJQANCHMSA-N
- InChI
- 1S/C20H19N3O2/c24-14-19(17-4-2-1-3-5-17)23-20(25)22-18-8-6-15(7-9-18)16-10-12-21-13-11-16/h1-13,19,24H,14H2,(H2,22,23,25)/t19-/m1/s1
- Sinonimi
- N-[(1S)-2-Hydroxy-1-phenylethyl]-N'-[4-(4-pyridinyl)phenyl]-urea | (S,Z)-N'-(2-hydroxy-1-phenylethyl)-N-(4-(pyridin-4...
- RKI 1447 dihydrochlorideSolido ≥99%(HPLC)● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: R287461Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 1-[(3-hydroxyphenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea;dihydrochloride
- SMILES
- C1=CC(=CC(=C1)O)CNC(=O)NC2=NC(=CS2)C3=CC=NC=C3.Cl.Cl
- InChIKey
- GBXLRAPHQIRDNS-UHFFFAOYSA-N
- InChI
- 1S/C16H14N4O2S.2ClH/c21-13-3-1-2-11(8-13)9-18-15(22)20-16-19-14(10-23-16)12-4-6-17-7-5-12;;/h1-8,10,21H,9H2,(H2,18,19,20,22);2*1H
- Sinonimi
- N-[(3-Hydroxyphenyl)methyl]-N'-[4-(4-pyridinyl)-2-thiazolyl]urea dihydrochloride | 7-Chloro-5-(1H-pyrrol-2-yl)-1H-ben...
- Fasudil HydrochlorideSolido Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: F122336Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline;hydrochloride
- SMILES
- C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl
- InChIKey
- LFVPBERIVUNMGV-UHFFFAOYSA-N
- InChI
- 1S/C14H17N3O2S.ClH/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14;/h1,3-5,7,11,15H,2,6,8-10H2;1H
- Sinonimi
- 5-((1,4-Diazepan-1-yl)sulfonyl)isoquinoline hydrochloride | 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline hydrochloride |...
- SR 3677CAS: 1072959-67-1 Numero EC: 802-637-7 PubChem CID: 25093235 Formula: C22H24N4O4 Peso molecolare: 408.45● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: S288304Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- N-[2-[2-(dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benzodioxine-3-carboxamide
- SMILES
- CN(C)CCOC1=C(C=CC(=C1)C2=CNN=C2)NC(=O)C3COC4=CC=CC=C4O3
- InChIKey
- OQWZIAVXCYIZNN-UHFFFAOYSA-N
- InChI
- show more
- Sinonimi
- N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl-2,3-dihydro-1,4-benzodioxin-2-carboxamide dihydrochloride
- Valeric acidAnalytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: V108271Visualizza prodottoPrezzi e dimensioni del pacchetto
Identificatori tecnici
- Nome IUPAC
- pentanoic acid
- SMILES
- CCCCC(=O)O
- InChIKey
- NQPDZGIKBAWPEJ-UHFFFAOYSA-N
- InChI
- 1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)
- Sinonimi
- Kyselina valerova | CHEBI:17418 | FT-0694066 | Valeric acid ( Pentanoic acid ) | VALPROIC ACID IMPURITY A [EP IMPURIT...
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Domande frequenti
How is the ROCK listing put together?
It draws on reported ROCK annotations within Cell Cycle/DNA Damage and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a ROCK modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the ROCK entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for ROCK compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For ROCK work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the ROCK compound I need is not listed?
Search by CAS number or SMILES first, since analogs of ROCK compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.