ROCK
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155 products
Popular Products
- GSK 269962, Inhibitor of Rho associated coiled-coil containing protein kinase 1;Inhibitor of Rho associated coiled-coil containing protein kinase 2CAS: 850664-21-0 Formula: C29H30N8O5 Molecular Weight: 570.6Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US Item #: G287476View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-6-yl]oxyphenyl]-4-(2-morpholin-4-ylethoxy)benzamide
- SMILES
- CCN1C2=CC(=NC=C2N=C1C3=NON=C3N)OC4=CC=CC(=C4)NC(=O)C5=CC=C(C=C5)OCCN6CCOCC6
- InChIKey
- YOVNFNXUCOWYSG-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- GTPL8037 | NSC-767348 | SCHEMBL1838346 | UNII-F89KMM7TE2 | N-(3-((2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo...
- NarciclasineCAS: 29477-83-6 Formula: C14H13NO7 Molecular Weight: 307.26● In Stock — US Item #: N125921View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (2S,3R,4S,4aR)-2,3,4,7-tetrahydroxy-3,4,4a,5-tetrahydro-2H-[1,3]dioxolo[4,5-j]phenanthridin-6-one
- SMILES
- C1OC2=C(O1)C(=C3C(=C2)C4=CC(C(C(C4NC3=O)O)O)O)O
- InChIKey
- LZAZURSABQIKGB-AEKGRLRDSA-N
- InChI
- 1S/C14H13NO7/c16-6-1-5-4-2-7-13(22-3-21-7)11(18)8(4)14(20)15-9(5)12(19)10(6)17/h1-2,6,9-10,12,16-19H,3H2,(H,15,20)/t6-,9+,10+,12-/m0/s1
- Synonyms
- Lycoricidin-A | MFCD01729949 | [1,3]Dioxolo[4,5-j]phenanthridin-6(2H)-one, 3,4,4a,5-tetrahydro-2,3,4,7-tetrahydroxy-,...
- GSK429286A, Inhibitor of Rho associated coiled-coil containing protein kinase 1;Inhibitor of ribosomal protein S6 kinase A1Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US Item #: G127028View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(6-fluoro-1H-indazol-5-yl)-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-pyridine-5-carboxamide
- SMILES
- CC1=C(C(CC(=O)N1)C2=CC=C(C=C2)C(F)(F)F)C(=O)NC3=C(C=C4C(=C3)C=NN4)F
- InChIKey
- OLIIUAHHAZEXEX-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- HMS3244C08 | HMS3654N12 | N6-ethanimidoyl-L-lysine dihydrochloride | dihydropyridone indazole amide 15 | HY-11000 | N...
- OXA 06 dihydrochloride● In Stock — US Item #: O288636View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[(2-fluorophenyl)methyl]-1-[4-(1H-pyrrolo[2,3-b]pyridin-4-yl)phenyl]methanamine;dihydrochloride
- SMILES
- C1=CC=C(C(=C1)CNCC2=CC=C(C=C2)C3=C4C=CNC4=NC=C3)F.Cl.Cl
- InChIKey
- ZRBCUSMZOWMVJS-UHFFFAOYSA-N
- InChI
- 1S/C21H18FN3.2ClH/c22-20-4-2-1-3-17(20)14-23-13-15-5-7-16(8-6-15)18-9-11-24-21-19(18)10-12-25-21;;/h1-12,23H,13-14H2,(H,24,25);2*1H
- Synonyms
- 2-Fluoro-N-[[4-(1H-pyrrolo[2,3-b]pyridin-4-yl)phenyl]methyl]benzenemethanamine dihydrochloride
- 5-(Piperazin-1-ylsulfonyl)isoquinoline● In Stock — US Item #: H275141View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-piperazin-1-ylsulfonylisoquinoline
- SMILES
- C1CN(CCN1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3
- InChIKey
- UPTYCYWTFGTCCG-UHFFFAOYSA-N
- InChI
- 1S/C13H15N3O2S/c17-19(18,16-8-6-14-7-9-16)13-3-1-2-11-10-15-5-4-12(11)13/h1-5,10,14H,6-9H2
- Synonyms
- 1-(5-Isoquinolinesulfonyl)piperazine | Piperazine, 1-(5-isoquinolinylsulfonyl)- | BDBM15203 | MFCD00209852 | NCGC0002...
- Valeric acidLiquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(GC)● In Stock — US Item #: V108272View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- pentanoic acid
- SMILES
- CCCCC(=O)O
- InChIKey
- NQPDZGIKBAWPEJ-UHFFFAOYSA-N
- InChI
- 1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)
- Synonyms
- n-Valeric acid | Pentanoic Acid
- Valeric acidMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. CP ? Chemically Pure grade — moderate purity above technical grade but below analytical. Use for general lab reactions where ultra-low impurities aren't critical. ≥98%● In Stock — US Item #: V108270View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- pentanoic acid
- SMILES
- CCCCC(=O)O
- InChIKey
- NQPDZGIKBAWPEJ-UHFFFAOYSA-N
- InChI
- 1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)
- Synonyms
- Kyselina valerova | CHEBI:17418 | FT-0694066 | Valeric acid ( Pentanoic acid ) | VALPROIC ACID IMPURITY A [EP IMPURIT...
- AS 1892802CAS: 928320-12-1 Formula: C20H19N3O2 Molecular Weight: 333.38● In Stock — US Item #: A288609View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[(1S)-2-hydroxy-1-phenylethyl]-3-(4-pyridin-4-ylphenyl)urea
- SMILES
- C1=CC=C(C=C1)C(CO)NC(=O)NC2=CC=C(C=C2)C3=CC=NC=C3
- InChIKey
- WDTFYYZHMRBVHK-LJQANCHMSA-N
- InChI
- 1S/C20H19N3O2/c24-14-19(17-4-2-1-3-5-17)23-20(25)22-18-8-6-15(7-9-18)16-10-12-21-13-11-16/h1-13,19,24H,14H2,(H2,22,23,25)/t19-/m1/s1
- Synonyms
- N-[(1S)-2-Hydroxy-1-phenylethyl]-N'-[4-(4-pyridinyl)phenyl]-urea | (S,Z)-N'-(2-hydroxy-1-phenylethyl)-N-(4-(pyridin-4...
- RKI 1447 dihydrochlorideSolid ≥99%(HPLC)● In Stock — US Item #: R287461View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[(3-hydroxyphenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea;dihydrochloride
- SMILES
- C1=CC(=CC(=C1)O)CNC(=O)NC2=NC(=CS2)C3=CC=NC=C3.Cl.Cl
- InChIKey
- GBXLRAPHQIRDNS-UHFFFAOYSA-N
- InChI
- 1S/C16H14N4O2S.2ClH/c21-13-3-1-2-11(8-13)9-18-15(22)20-16-19-14(10-23-16)12-4-6-17-7-5-12;;/h1-8,10,21H,9H2,(H2,18,19,20,22);2*1H
- Synonyms
- N-[(3-Hydroxyphenyl)methyl]-N'-[4-(4-pyridinyl)-2-thiazolyl]urea dihydrochloride | 7-Chloro-5-(1H-pyrrol-2-yl)-1H-ben...
- Fasudil HydrochlorideSolid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US Item #: F122336View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline;hydrochloride
- SMILES
- C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl
- InChIKey
- LFVPBERIVUNMGV-UHFFFAOYSA-N
- InChI
- 1S/C14H17N3O2S.ClH/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14;/h1,3-5,7,11,15H,2,6,8-10H2;1H
- Synonyms
- 5-((1,4-Diazepan-1-yl)sulfonyl)isoquinoline hydrochloride | 5-(1,4-diazepan-1-ylsulfonyl)isoquinoline hydrochloride |...
- SR 3677CAS: 1072959-67-1 EC Number: 802-637-7 PubChem CID: 25093235 Formula: C22H24N4O4 Molecular Weight: 408.45● In Stock — US Item #: S288304View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[2-[2-(dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benzodioxine-3-carboxamide
- SMILES
- CN(C)CCOC1=C(C=CC(=C1)C2=CNN=C2)NC(=O)C3COC4=CC=CC=C4O3
- InChIKey
- OQWZIAVXCYIZNN-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl-2,3-dihydro-1,4-benzodioxin-2-carboxamide dihydrochloride
- Valeric acidAnalytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.● In Stock — US Item #: V108271View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- pentanoic acid
- SMILES
- CCCCC(=O)O
- InChIKey
- NQPDZGIKBAWPEJ-UHFFFAOYSA-N
- InChI
- 1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)
- Synonyms
- Kyselina valerova | CHEBI:17418 | FT-0694066 | Valeric acid ( Pentanoic acid ) | VALPROIC ACID IMPURITY A [EP IMPURIT...
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How is the ROCK listing put together?
It draws on reported ROCK annotations within Cell Cycle/DNA Damage and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a ROCK modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the ROCK entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for ROCK compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For ROCK work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the ROCK compound I need is not listed?
Search by CAS number or SMILES first, since analogs of ROCK compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.