Ciclo cellulare/Danno al DNA - Piccoletto Supplier | High Purity

Prodotti

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Griseofulvin, Tubulin inhibitor
CAS: 126-07-8 Numero EC: 204-767-4 Formula: C₁₇H₁₇ClO₆ Peso molecolare: 352.77

Analytical standard ?

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: G101269
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(2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione

SMILES

CC1CC(=O)C=C(C12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC

InChIKey

DDUHZTYCFQRHIY-RBHXEPJQSA-N

InChI

1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1

Sinonimi
CCRIS 320 | Grifulin | (2S-trans)-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-...
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MK-1775, Serine/threonine-protein kinase WEE1 inhibitor
CAS: 955365-80-7 Numero EC: 680-342-0 Formula: C₂₇H₃₂N₈O₂ Peso molecolare: 500.61

Moligand™ ? ≥98%

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: M127160
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1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one

SMILES

CC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC=C(C=C4)N5CCN(CC5)C)O

InChIKey

BKWJAKQVGHWELA-UHFFFAOYSA-N

InChI

1S/C27H32N8O2/c1-5-13-34-25(36)21-18-28-26(29-19-9-11-20(12-10-19)33-16-14-32(4)15-17-33)31-24(21)35(34)23-8-6-7-22(30-23)27(2,3)37/h5-12,18,37H,1,13-show more

Sinonimi
MK-1775(AZD-1775,Adavosertib) | 2-allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenyla...
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Griseofulvin
CAS: 126-07-8 Numero EC: 204-767-4 Formula: C₁₇H₁₇ClO₆ Peso molecolare: 352.77

Solido ≥97%

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: G101270
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(2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione

SMILES

CC1CC(=O)C=C(C12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC

InChIKey

DDUHZTYCFQRHIY-RBHXEPJQSA-N

InChI

1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1

Sinonimi
Grisovin | Curling factor | Fulcin | Likuden | Grizeofulvin | Griseofulvina | Grifulvin | Grysio | Delmofulvina | Gri...
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PD0166285, Inhibitor of epidermal growth factor receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of platelet derived growth factor receptor beta;Inhibitor of protein kinase; membrane associated tyrosine/threonine 1;Inhibitor of SRC proto-oncogene;
CAS: 185039-89-8 PubChem CID: 5311382 Formula: C₂₆H₂₇Cl₂N₅O₂ Peso molecolare: 512.43

Moligand™ ? ≥99%

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: P276244
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6-(2,6-dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one

SMILES

CCN(CC)CCOC1=CC=C(C=C1)NC2=NC=C3C=C(C(=O)N(C3=N2)C)C4=C(C=CC=C4Cl)Cl

InChIKey

IFPPYSWJNWHOLQ-UHFFFAOYSA-N

InChI

1S/C26H27Cl2N5O2/c1-4-33(5-2)13-14-35-19-11-9-18(10-12-19)30-26-29-16-17-15-20(25(34)32(3)24(17)31-26)23-21(27)7-6-8-22(23)28/h6-12,15-16H,4-5,13-14H2show more

Sinonimi
AKOS022190406 | SCHEMBL133914 | Kinome_3263 | BCP20228 | EX-A4179 | 6-(2,6-Dichloro-phenyl)-2-[4-(2-diethylamino-etho...
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Bosutinib Isomer 1, Free Base
CAS: 1391063-17-4 PubChem CID: 5328940 Formula: C26H29Cl2N5O3 Peso molecolare: 530.45

◐ .Su ordinazione · 8–12 settimane Oggetto #: B330520
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Sinonimi
Bosutinib,SKI-606 | BSPBio_001023 | NCGC00241107-03 | NSC799367 | NSC-799367 | 4-(2,4-Dichloro-5-methoxy-phenylamino)...
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Griseofulvin, Tubulin inhibitor
CAS: 126-07-8 Numero EC: 204-767-4 Formula: C₁₇H₁₇ClO₆ Peso molecolare: 352.77

Liquido 10mM in DMSO

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: G421095
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(2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione

SMILES

CC1CC(=O)C=C(C12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC

InChIKey

DDUHZTYCFQRHIY-RBHXEPJQSA-N

InChI

1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1

Sinonimi
griseofulvin|126-07-8|Amudane|(+)-Griseofulvin|Griseofulvinum|Grisactin|Grifulvin|Grisefuline|Griseofulvina|Grisofulv...
Lista dei desideri Aggiungi al confronto
PD0166285, Inhibitor of epidermal growth factor receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of platelet derived growth factor receptor beta;Inhibitor of protein kinase; membrane associated tyrosine/threonine 1;Inhibitor of SRC proto-oncogene;
CAS: 185039-89-8 PubChem CID: 5311382 Formula: C₂₆H₂₇Cl₂N₅O₂ Peso molecolare: 512.43

Moligand™ ? 10mM in DMSO

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: P422267
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6-(2,6-dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one

SMILES

CCN(CC)CCOC1=CC=C(C=C1)NC2=NC=C3C=C(C(=O)N(C3=N2)C)C4=C(C=CC=C4Cl)Cl

InChIKey

IFPPYSWJNWHOLQ-UHFFFAOYSA-N

InChI

1S/C26H27Cl2N5O2/c1-4-33(5-2)13-14-35-19-11-9-18(10-12-19)30-26-29-16-17-15-20(25(34)32(3)24(17)31-26)23-21(27)7-6-8-22(23)28/h6-12,15-16H,4-5,13-14H2show more

Sinonimi
AKOS022190406 | SCHEMBL133914 | Kinome_3263 | BCP20228 | EX-A4179 | 6-(2,6-Dichloro-phenyl)-2-[4-(2-diethylamino-etho...
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Wee1 inhibitor
CAS: 622855-37-2 PubChem CID: 10384072 Formula: C₂₀H₁₁ClN₂O₃ Peso molecolare: 362.77

◐ .Su ordinazione · 8–12 settimane Oggetto #: W342954
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4-(2-chlorophenyl)-9-hydroxy-6H-pyrrolo[3,4-c]carbazole-1,3-dione

SMILES

C1=CC=C(C(=C1)C2=CC3=C(C4=C(N3)C=CC(=C4)O)C5=C2C(=O)NC5=O)Cl

InChIKey

DPEXRCOBPACFOO-UHFFFAOYSA-N

InChI

1S/C20H11ClN2O3/c21-13-4-2-1-3-10(13)11-8-15-16(18-17(11)19(25)23-20(18)26)12-7-9(24)5-6-14(12)22-15/h1-8,22,24H,(H,23,25,26)

Sinonimi
BDBM50192371 | Wee1 Inhibitor I | Wee1-Inhibitor-I | MS-25768 | HY-108343 | Wee1 Inhibitor-I | SCHEMBL5828030 | Wee1 ...
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Azenosertib (Zn-C3), Inhibitor of WEE1 G2 checkpoint kinase
CAS: 2376146-48-2 Numero EC: 189-014-7 PubChem CID: 139467635 Formula: C₂₉H₃₄N₈O₂ Peso molecolare: 526.63

Moligand™ ? ≥98%

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: A607901
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1-[(7R)-7-ethyl-7-hydroxy-5,6-dihydrocyclopenta[b]pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one

SMILES

O=c1n(CC=C)n(c2ccc3CC[C@@](CC)(O)c3n2)c2nc(Nc3ccc(N4CCN(C)CC4)cc3)ncc12

InChIKey

OXTSYWDBUVRXFF-GDLZYMKVSA-N

InChI

1S/C29H34N8O2/c1-4-14-36-27(38)23-19-30-28(31-21-7-9-22(10-8-21)35-17-15-34(3)16-18-35)33-26(23)37(36)24-11-6-20-12-13-29(39,5-2)25(20)32-24/h4,6-11,1show more

Sinonimi
compound 16 [PMID: 34423975] | azenosertib | Azenosertib [INN] | EX-A6113 | 9J13XU96Z1 | (R)-2-allyl-1-(7-ethyl-7-hyd...
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WEE1-IN-5
CAS: 2243882-74-6 Formula: C₂₆H₂₈Cl₂N₆O Peso molecolare: 511.45

≥99%

◐ .Su ordinazione · 8–12 settimane Oggetto #: W648831
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SMILES

O=C1C2=CN=C(NC3=CC=C(C4CCN(CC4)C)C(C)=C3)N=C2N(CN1C5=C(Cl)C=CC=C5Cl)C
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RP-6306
CAS: 2719793-90-3 Formula: C₁₈H₂₀N₄O₂ Peso molecolare: 324.38

≥99%

◐ .Su ordinazione · 8–12 settimane Oggetto #: R646400
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WEE1-IN-3
CAS: 2272976-28-8 PubChem CID: 137471996 Formula: C₂₈H₃₁N₇O₂ Peso molecolare: 497.59

≥98%

◐ .Su ordinazione · 8–12 settimane Oggetto #: W648627
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1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[(2-methylspiro[1,3-dihydroisoquinoline-4,1'-cyclopropane]-7-yl)amino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidishow more

SMILES

CC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC5=C(C=C4)C6(CC6)CN(C5)C)O

InChIKey

JSZFIXAMFNNRKS-UHFFFAOYSA-N

InChI

1S/C28H31N7O2/c1-5-13-34-25(36)20-15-29-26(32-24(20)35(34)23-8-6-7-22(31-23)27(2,3)37)30-19-9-10-21-18(14-19)16-33(4)17-28(21)11-12-28/h5-10,14-15,37Hshow more

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Domande frequenti

How is the Wee1 listing put together?

It draws on reported Wee1 annotations within Cell Cycle/DNA Damage and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.

How do I choose a Wee1 modulator for my assay?

Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Wee1 entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.

Which specifications matter most for Wee1 compounds?

Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Wee1 work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

What if the Wee1 compound I need is not listed?

Search by CAS number or SMILES first, since analogs of Wee1 compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.