Panoramica Specifications Nomi e identificatori Documentazione Advanced Data Taxonomic Classification Struttura 3D Obiettivi associati (umani) Obiettivi associati (non umani) Meccanismi d'azione Certificati (CoA, COO, BSE/TSE e tabella di analisi) Proprietà chimiche e fisiche Domande frequenti e articoli Citations of This Product Calcolatori di soluzioni Recensioni

🧪

Why this grade

Suitable for molecular biology, ≥98.5%(GC) Suitable for molecular biology for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature,Desiccated Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 1843 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Panoramica

Sodium dodecyl sulfate (SDS), also known as sodium lauryl sulfate, is a versatile anionic surfactant with a broad range of applications in cell biology, biochemistry, and various industries. Its amphiphilic nature, characterized by a hydrophobic hydrocarbon tail and a hydrophilic sulfate head group, makes it an effective detergent capable of solubilizing and denaturing proteins, lipids, and other hydrophobic molecules.
In protein biochemistry, SDS plays a pivotal role in protein extraction and SDS-PAGE (sodium dodecyl sulfate-polyacrylamide gel electrophoresis). Its ability to denature proteins by disrupting their secondary and tertiary structures allows for their uniform migration through a polyacrylamide gel matrix based on their molecular weight. This technique, SDS-PAGE, has become an indispensable tool for analyzing protein size and purity.
Beyond protein analysis, SDS also finds applications in nucleic acid extraction and hybridization techniques. Its detergent properties aid in the lysis of cells and the solubilization of cellular components, facilitating the extraction of DNA and RNA. This makes SDS a valuable reagent in various molecular biology protocols, including PCR (polymerase chain reaction) and Southern blotting. Sodium dodecyl sulfate stands as a versatile and widely used surfactant with a diverse range of applications due to its ability to solubilize, denature, and separate biological molecules for cell biology and biochemical research.

Specifications

Sinonimi

Specifiche e purezza

Suitable for molecular biology, ≥98.5%(GC)

Meccanismi biochimici e fisiologici

Sodium dodecyl sulfate (SDS) is an anionic detergent that can form complexes with proteins through hydrophobic interactions. Previous studies have reported that the hydrodynamic function of protein SDS complexes is controlled by the length of their polype

Condizioni di conservazione di stoccaggio

Room temperature,Desiccated

Spedito in

Normal

Grado

Suitable for molecular biology

Purezza

≥98.5%(GC)

Nomi e identificatori

Pubchem Sid

508812551

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/508812551

Sorrisi canonici

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

IUPAC Name

sodium;dodecyl sulfate

InChIKey

DBMJMQXJHONAFJ-UHFFFAOYSA-M

INCHI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

Isomeri SMILES

CCCCCCCCCCCCOS(=O)(=O)[O-].[Na+]

Numero UN

1325

Gruppo di imballaggio

III

Peso molecolare

288.38

Documentazione

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - Classe Organic sulfuric acids and derivatives
    - Subclass Sulfuric acid esters

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
Classe	Organic sulfuric acids and derivatives
Subclass	Sulfuric acid esters
Intermediate Tree Nodes	Not available
Direct Parent	Sulfuric acid monoesters
Alternative Parents	Alkyl sulfates Organooxygen compounds Organic sodium salts Organic oxides Hydrocarbon derivatives
Molecular Framework	Aliphatic acyclic compounds
Substituents	Alkyl sulfate - Sulfate-ester - Sulfuric acid monoester - Organic alkali metal salt - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organic sodium salt - Organic salt - Organooxygen compound - Aliphatic acyclic compound
Descrizione	This compound belongs to the class of organic compounds known as sulfuric acid monoesters. These are organic compounds containing the sulfuric acid monoester functional group, with the generic structure ROS(O)(=O)=O, (R=organyl group).
External Descriptors	alkyl sulfate
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Struttura 3D

Obiettivi associati (umani)

VDR Tclin Vitamin D receptor (26531 Activities)

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TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)

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PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)

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PPARA Tclin Peroxisome proliferator-activated receptor alpha (9197 Activities)

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THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)

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CXCL8 Tchem Interleukin-8 (642 Activities)

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GLA Tclin Alpha-galactosidase A (5444 Activities)

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NR1H4 Tclin Bile acid receptor FXR (6228 Activities)

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EPHX2 Tchem Epoxide hydratase (3844 Activities)

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AKT1 Tchem Serine/threonine-protein kinase AKT (9192 Activities)

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Homo sapiens (32628 Activities)

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HCT-116 (91556 Activities)

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Lymphoblastoid cell (5959 Activities)

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LMNA Tbio Prelamin-A/C (36751 Activities)

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RECQL Tbio ATP-dependent DNA helicase Q1 (5575 Activities)

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HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)

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GMNN Tbio Geminin (128009 Activities)

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USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)

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Obiettivi associati (non umani)

Cruzipain (33337 Activities)

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Mapk1 MAP kinase ERK2 (650 Activities)

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Pseudomonas aeruginosa (123386 Activities)

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Enterobacter cloacae (7976 Activities)

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Staphylococcus aureus (210822 Activities)

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Acinetobacter baumannii (41033 Activities)

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Escherichia coli (133304 Activities)

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Proteus mirabilis (3894 Activities)

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Mycobacterium tuberculosis (203094 Activities)

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Enterococcus faecalis (29875 Activities)

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Candida albicans (78123 Activities)

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Nakaseomyces glabratus (9108 Activities)

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Candida parapsilosis (8521 Activities)

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Rattus norvegicus (775804 Activities)

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RAW264.7 (28094 Activities)

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lef Anthrax lethal factor (7585 Activities)

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GCN5 Histone acetyltransferase GCN5 (89 Activities)

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Luciferin 4-monooxygenase (66902 Activities)

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Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

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Meccanismi d'azione

Certificati (CoA, COO, BSE/TSE e tabella di analisi)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

23 results found

Lot Number	Certificate Type	Data	Oggetto
H2611351	Certificate of Analysis	Aug 20, 2026	S118591
H2611325	Certificate of Analysis	Aug 20, 2026	S118591
H2611316	Certificate of Analysis	Aug 20, 2026	S118591
F2608119	Certificate of Analysis	Jun 15, 2026	S118591
B2624557	Certificate of Analysis	Mar 06, 2026	S118591
B2624558	Certificate of Analysis	Mar 06, 2026	S118591
B2624556	Certificate of Analysis	Mar 06, 2026	S118591
K2327349	Certificate of Analysis	Sep 04, 2025	S118591
K2314028	Certificate of Analysis	Jun 25, 2025	S118591
K2314027	Certificate of Analysis	Jun 25, 2025	S118591
K2314026	Certificate of Analysis	Jun 25, 2025	S118591
J2310379	Certificate of Analysis	Oct 18, 2023	S118591
J2310378	Certificate of Analysis	Oct 18, 2023	S118591
J2310377	Certificate of Analysis	Oct 18, 2023	S118591
I2315253	Certificate of Analysis	Sep 19, 2023	S118591
I2315252	Certificate of Analysis	Sep 19, 2023	S118591
I2315251	Certificate of Analysis	Sep 19, 2023	S118591
J2210262	Certificate of Analysis	Oct 15, 2022	S118591
F2224167	Certificate of Analysis	Jul 04, 2022	S118591
C2119063	Certificate of Analysis	Dec 15, 2021	S118591
F2210685	Certificate of Analysis	Dec 15, 2021	S118591
F2224169	Certificate of Analysis	Dec 15, 2021	S118591
F2224168	Certificate of Analysis	Dec 15, 2021	S118591

Proprietà chimiche e fisiche

Sensibilità	Hygroscopic
Punto di fusione (°C)	204-207°C
Peso molecolare	288.380 g/mol
XLogP3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	12
Exact Mass	288.137 Da
Monoisotopic Mass	288.137 Da
Topological Polar Surface Area	74.800 Å²
Heavy Atom Count	18
Formal Charge	0
Complexity	249.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

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NaOH Sodium Hydroxide

Role of Alkyl Glucosides APG in Cleaning Formulations: Structural Features, Core Performance, and Selection Considerations

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Decyl Glucoside Lauryl Glucoside Coco-Glucoside Caprylyl/Capryl Glucoside

AES (Fatty Alcohol Polyoxyethylene Ether Sulfate) in Personal and Home-Care Cleansing Formulations: An Analysis of Structure, Performance, and Low-Temperature Flowability

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Surfactants cosmetics Daily chemical cleaning

Why Limonene Can Soften Greasy Soils Yet Is Difficult to Dissolve in Water: Understanding the Cleaning Mechanism and Formulation Applications of Naturally Derived Solvents from Molecular Structure

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Solvents Natural source solvents Oil friendly cleaning solvent

Degreasing Agents from a Molecular-Structure Perspective: How AEO, APG, and Related Surfactants Can Replace Nonylphenol Ethoxylates (NPE)

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Surfactants Daily chemical cleaning Degreaser

Understanding CAPB from Its Structure: How Cocamidopropyl Betaine Improves Foam, Enhances Mildness, and Supports Thickening

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Surfactants Daily chemical cleaning CAPB

Interfacial Mechanism and Formulation Applications of AEO-9 (Fatty Alcohol Polyoxyethylene Ether): An Analysis of Emulsification, Wetting, Oil Soil Removal, and Co-Formulation Compatibility

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AEO-9

More Than a pH Adjuster: Mechanisms, Selection Logic, and Alternative Acid Source Analysis of Citric Acid in Home-Care Cleaning

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Citric Acid

Wetting and Penetration Mechanisms of Penetrating Agents in Household and Personal Care Cleaning Systems: Representative Structural Analysis Using JFC, OEP-70, and DOSS as Examples

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Penetrating Agents JFC OEP-70 DOSS

What Are the Differences Among Sodium Dodecylbenzenesulfonate/SDBS, LAS, and Sodium α-Olefin Sulfonate/AOS: A Comparative Overview of Synthesis, Structure, Mechanism of Action, and Formulation Selection

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SDBS LAS Linear Alkylbenzene Sulfonate

From Structure to Selection: Mechanisms and Application Assessment of Low-Foam Oil and Wax Removal with Fatty Acid Methyl Ester Ethoxylates (FMEE)

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FMEE MEE

Sodium Metasilicate in Cleaning Applications: Hydration-Form Differences, Mechanisms of Action, and Selection Logic

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Na₂SiO₃ Sodium Metasilicate

Analysis of the Foaming Performance Differences Between K12 and AOS: Structure, Acid–Base Stability, and Formulation Selection

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K12 AOS

Understanding Anionic Surfactants in Household and Personal-Care Formulations from a Structural Perspective: Structural and Performance Differences among Representative Raw Materials such as LAS, AES, K12, AOS, MES, and FMES

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K12 LAS AOS AES MES FMES

Structural Characteristics, Low-Temperature Flowability, and Home-Care Cleaning Applications of Palm-Derived Isomeric Alcohol Polyoxyethylene Ether PLE-S9

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PLE-S9

The Structural Logic of Amphoteric Surfactants: Representative Ingredients, Performance Mechanisms, and Formulation Applications in Personal Care and Home Care

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Zwitterionic

Mechanisms and Troubleshooting of Foam Reduction in Personal and Household Care Formulations: Film Rupture, Weak Interfacial Films, Insufficient Surfactant Supply, and Phase-State Disturbance

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Foam performance

Why Are Daily Chemical Products Prone to Viscosity Thinning in Summer? Core Mechanisms, Troubleshooting Methods, and Solutions

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Daily chemical products Return to thinning

Application of Conductive Carbon Black in Coatings: Selection Criteria, Dispersion Control, and Conductive Network Construction

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resin Coating film Paint Conductive Carbon Black

Key Variable in the Long-Term Stability of Waterborne Pigment Concentrates: How Dispersant Molecular Weight Distribution (MWD) Affects Pigment Dispersion, Surface Adsorption-Layer Formation, and Storage Stability

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Dispersant Water-based color paste Surface of pigment particles

Understanding the Four Classes of Surfactants Through Molecular Charge: Application Logic of Anionic, Cationic, Amphoteric and Zwitterionic, and Nonionic Surfactants in Personal Care and Home Care

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Surfactants

Bacterial Cell Wall Degradation Technology

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SDS Proteinase K Cell lysis EDTA Protoplasts Lysozyme Gram-negative bacteria Gram-positive bacteria Bacterial cell wall Peptidoglycan Lysostaphin

Probiotics, Prebiotics, and Postbiotics in Skin Care: Conceptual Distinctions, Mechanisms of Action, and Their Applications in the Care of Dry, Itchy, and Rough Skin

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skin care Probiotics

Protective and Potential Reparative Mechanisms of Prinsepia utilis Seed Oil on the Skin Barrier: Fatty Acid Composition, Epidermal Lipid Metabolism, and Research Evidence

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Seed Oil Prinsepia Utilis Seed Oil

Mechanism of Action of Porous Silica in Oil-Control Loose Powder: Pore Structure, Capillary Imbibition, and Surface Modification

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Silicon dioxide

Structure, Stratum Corneum Distribution, and Stratum Corneum Conditioning Mechanism of Capryloyl Salicylic Acid: Barrier Effects and Safety Evaluation

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Capryloyl Salicylic Acid Lipohydroxy Acid LHA

Gentiana Root Extract and Gentiopicroside: Chemical Composition, Antioxidant and Inflammation-Modulating Mechanisms, and Their Potential Effects on Skin Barrier Homeostasis

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Gentiana manshurica Gentiana scabra Gentiana triflora Gentiana rigescens Gentiana Root Extract Gentiopicroside

Mechanisms by Which Fructan-Rich Ophiopogon japonicus Tuberous Root Extract Supports Skin Moisturization and Barrier Function

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Ophiopogon japonicus Root Extract Ophiopogon polysaccharides

Phase-Partitioning Principles, System Differences, and Application Selection in Phenol-Based DNA and RNA Extraction

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RNA extraction DNA extraction Quality control phenol-based extraction phenol-chloroform isoamyl alcohol acidic phenol guanidinium thiocyanate liquid-liquid partitioning nucleic acid purification

What Is “Plant Collagen”? Distinguishing Ingredient Types, Structural Differences, Production Methods, and Skincare Effects

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Plant Collagen

What Is Direct Compression? Process Characteristics, Suitability Criteria, and Excipient Selection

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Direct Compression Wet granulation and tablet compression Dry granulation and tablet compression

Differences Between Animal-Derived Collagen and Recombinant Collagen in Skincare: Sequence and Structure, Safety, Skin Effects, and Evidence Evaluation

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Animal-Derived Collagen Recombinant Human Collagen Recombinant Humanized Collagen Triple Helix Immunogenicity Skin Repair Transepidermal Water Loss

Stratum Corneum Penetration and Skin Mechanisms of Panthenol: Moisturization, Barrier Repair, and Soothing Effects

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Panthenol pantothenic acid Vitamin B5 D-panthenol

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