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· · COA & SDS available for every product · Same-day shipping on in-stock items Tirasemtiv (CK-2017357) - Moligand™, 10mM in DMSO , CAS No.1005491-05-3
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO Synonyms
1-(1-Ethylpropyl)-6-ethynyl-1,3-dihydro-2H-imidazo(4,5-b)pyrazin-2-one | AC-35962 | RSQGZEAXODVTOL-UHFFFAOYSA-N | 5GD84Y125G | Tirasemtiv [USAN:INN] | BCP27991 | 1-(1-Ethylpropyl)-6-ethynyl-1,3-dihydro-2H-imidazo[4,5-b]pyrazin-2-one | AKOS027250724 | MFCD
Shipped In
Dry ice packs + Cold packs
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Why this grade Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview Information
Tirasemtiv (CK-2017357, CK-357) is a directfast skeletal muscle troponinactivator that sensitizes the sarcomere to calcium.
Specifications Synonyms
1-(1-Ethylpropyl)-6-ethynyl-1, 3-dihydro-2H-imidazo(4, 5-b)pyrazin-2-one | AC-35962 | RSQGZEAXODVTOL-UHFFFAOYSA-N | 5GD84Y125G | Tirasemtiv [USAN:INN] | BCP27991 | 1-(1-Ethylpropyl)-6-ethynyl-1, 3-dihydro-2H-imidazo[4, 5-b]pyrazin-2-one | AKOS027250724 | MFCD
Specifications & Purity
Moligand™, 10mM in DMSO
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Product Properties Names and Identifiers Pubchem Sid 528767509 Canonical Smiles CCC(CC)N1C2=NC(=CN=C2NC1=O)C#C IUPAC Name 5-ethynyl-3-pentan-3-yl-1H-imidazo[4,5-b]pyrazin-2-one InChIKey RSQGZEAXODVTOL-UHFFFAOYSA-N INCHI 1S/C12H14N4O/c1-4-8-7-13-10-11(14-8)16(12(17)15-10)9(5-2)6-3/h1,7,9H,5-6H2,2-3H3,(H,13,15,17) Isomeric SMILES CCC(CC)N1C2=NC(=CN=C2NC1=O)C#C Alternate CAS 1005491-05-3 PubChem CID 23729157 MeSH Entry Terms CK-2017357;tirasemtiv Molecular Weight 230.27
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Imidazopyrazines Subclass Not available Intermediate Tree Nodes Not available Direct Parent Imidazopyrazines Alternative Parents Pyrazines N-substituted imidazoles Heteroaromatic compounds Ureas Azacyclic compounds Acetylides Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents Imidazopyrazine - N-substituted imidazole - Pyrazine - Azole - Imidazole - Heteroaromatic compound - Urea - Acetylide - Azacycle - Organic nitrogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organic oxide - Organic oxygen compound - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as imidazopyrazines. These are organic heteropolycyclic compounds containing a pyrazine ring fused to an imidazole ring. These also include hydrogenated derivatives of the imidazopyrazine moiety. Imidazole is 5-membered ring consisting of three carbon atoms, and two nitrogen centers at the 1- and 3-positions. Pyrazine is a 6-membered ring consisting of six carbon atoms and two nitrogen centers at ring positions 1 and 4. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Molecular Weight 230.270 g/mol XLogP3 1.400 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 3 Rotatable Bond Count 4 Exact Mass 230.117 Da Monoisotopic Mass 230.117 Da Topological Polar Surface Area 58.100 Ų Heavy Atom Count 17 Formal Charge 0 Complexity 344.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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