≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
3-Hydroxymethyl-β-carboline is a polyaromatic small molecule that demonstrates antagonism of the effects of benzodiazepine binding activity. 3-Hydroxymethyl-beta-carboline antagonizes the anxiolytic and anticonvulsant actions of benzodiazepines, a property common to other 3-substitued carboline compounds including the inverse agonist Ethyl β-carboline-3-carboxylate . The sedative effects of the benzodiazepines are antagonized by 3-Hydroxymethyl-beta-carboline at a dose sufficiently low to have no intrinsic effect on sleep. Higher doses of 3-Hydroxymethyl-β-carboline were shown to increase wakefulness and sleep latency, suggesting that an effect inverse to benzodiazepine sedation is presented by 3-Hydroxymethyl-beta-carboline activity.
| Pubchem Sid | 488195389 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488195389 |
| Canonical Smiles | C1=CC=C2C(=C1)C3=C(N2)C=NC(=C3)CO |
| IUPAC Name | 9H-pyrido[3,4-b]indol-3-ylmethanol |
| InChIKey | CPBYHTDUBNSBQM-UHFFFAOYSA-N |
| INCHI | 1S/C12H10N2O/c15-7-8-5-10-9-3-1-2-4-11(9)14-12(10)6-13-8/h1-6,14-15H,7H2 |
| Isomeric SMILES | C1=CC=C2C(=C1)C3=C(N2)C=NC(=C3)CO |
| WGK Germany | 3 |
| Molecular Weight | 198.22 |
| Reaxy-Rn | 746164 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=746164&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Indoles and derivatives |
| Subclass | Pyridoindoles |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Beta carbolines |
| Alternative Parents | Indoles Pyridines and derivatives Benzenoids Pyrroles Heteroaromatic compounds Azacyclic compounds Primary alcohols Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives Aromatic alcohols |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Beta-carboline - Indole - Pyridine - Benzenoid - Pyrrole - Heteroaromatic compound - Azacycle - Hydrocarbon derivative - Aromatic alcohol - Alcohol - Organopnictogen compound - Primary alcohol - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as beta carbolines. These are compounds containing a 9H-pyrido[3,4-b]indole moiety. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 E2527048 | Certificate of Analysis | Jun 02, 2023 | H351104 |
| F2316359 | Certificate of Analysis | Jun 02, 2023 | H351104 |
| F2316413 | Certificate of Analysis | Jun 02, 2023 | H351104 |
| F2316418 | Certificate of Analysis | Jun 02, 2023 | H351104 |
| F2316421 | Certificate of Analysis | Jun 02, 2023 | H351104 |
| F2316425 | Certificate of Analysis | Jun 02, 2023 | H351104 |
| F2316426 | Certificate of Analysis | Jun 02, 2023 | H351104 |
| Solubility | Soluble in: ethanol; DMSO |
|---|---|
| Melt Point(°C) | 215-219° C |
| Molecular Weight | 198.220 g/mol |
| XLogP3 | 2.300 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 1 |
| Exact Mass | 198.079 Da |
| Monoisotopic Mass | 198.079 Da |
| Topological Polar Surface Area | 48.900 Ų |
| Heavy Atom Count | 15 |
| Formal Charge | 0 |
| Complexity | 234.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
