PERK
55 produtos
Produtos
- GSK PERK inhibitor, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 3;Inhibitor of myosin light chain kinase 2CAS: 1337531-89-1 Fórmula: C24H19F4N5O Peso molecular: 469.43Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● Em estoque — Armazém nos EUA, envio para a EU* Item #: G355474Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydroindol-1-yl]-2-[3-fluoro-5-(trifluoromethyl)phenyl]ethanone
- SMILES
- CN1C=C(C2=C(N=CN=C21)N)C3=CC4=C(C=C3)N(CC4)C(=O)CC5=CC(=CC(=C5)F)C(F)(F)F
- InChIKey
- PXVQGBJMIQCDEX-UHFFFAOYSA-N
- InChI
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- Sinónimos
- 1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-2, 3-dihydroindol-1-yl]-2-[3-fluoro-5-(trifluoromethyl)phenyl]eth...
- GSK2606414CAS: 1337531-36-8 Fórmula: C24H20F3N5O Peso molecular: 451.44Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● Em estoque — Armazém nos EUA, envio para a EU* Item #: G125654Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydroindol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone
- SMILES
- CN1C=C(C2=C(N=CN=C21)N)C3=CC4=C(C=C3)N(CC4)C(=O)CC5=CC(=CC=C5)C(F)(F)F
- InChIKey
- SIXVRXARNAVBTC-UHFFFAOYSA-N
- InChI
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- Sinónimos
- AC-29016 | 1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)indolin-1-yl)-2-(3-(trifluoromethyl)phenyl)ethanone...
- GSK2656157, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 3CAS: 1337532-29-2 Fórmula: C23H21FN6O Peso molecular: 416.45Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● Em estoque — Armazém nos EUA, envio para a EU* Item #: G276179Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-(6-methylpyridin-2-yl)ethanone
- SMILES
- CC1=NC(=CC=C1)CC(=O)N2CCC3=C2C=CC(=C3F)C4=CN(C5=NC=NC(=C45)N)C
- InChIKey
- PRWSIEBRGXYXAJ-UHFFFAOYSA-N
- InChI
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- Sinónimos
- 1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydro-1H-indol-1-yl]-2-(6-methyl-2-pyridinyl)e...
- ONO 8130, Antagonist of EP 1 receptorCAS: 459841-96-4 Fórmula: C25H28N2O5S2 Peso molecular: 500.63Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)◐ .Sob encomenda · 8–12 semanas Item #: O287851Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 4-[[6-[2-methylpropyl-[(4-methyl-1,3-thiazol-2-yl)sulfonyl]amino]-2,3-dihydro-1H-inden-5-yl]oxymethyl]benzoic acid
- SMILES
- CC1=CSC(=N1)S(=O)(=O)N(CC(C)C)C2=C(C=C3CCCC3=C2)OCC4=CC=C(C=C4)C(=O)O
- InChIKey
- IOXMDBQCUCDLAF-UHFFFAOYSA-N
- InChI
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- Sinónimos
- AC-36636 | BDBM190564 | 4-[[6-[2-methylpropyl-[(4-methyl-1,3-thiazol-2-yl)sulfonyl]amino]-2,3-dihydro-1H-inden-5-yl]o...
- VU 0424465, Agonist of mGlu 5 receptor;Allosteric modulator of mGlu 5 receptorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)◐ .Sob encomenda · 8–12 semanas Item #: V286883Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 5-[2-(3-fluorophenyl)ethynyl]-N-[(2R)-3-hydroxy-3-methylbutan-2-yl]pyridine-2-carboxamide
- SMILES
- CC(C(C)(C)O)NC(=O)C1=NC=C(C=C1)C#CC2=CC(=CC=C2)F
- InChIKey
- ZPKZAFDYFVJULO-CYBMUJFWSA-N
- InChI
- 1S/C19H19FN2O2/c1-13(19(2,3)24)22-18(23)17-10-9-15(12-21-17)8-7-14-5-4-6-16(20)11-14/h4-6,9-13,24H,1-3H3,(H,22,23)/t13-/m1/s1
- Sinónimos
- 5-[2-(2-(3-Fluorophenyl)ethynyl]-N-[(1R)-2-hydroxy-1,2-dimethylpropyl]-2-pyridinecarboxamide
- AMG PERK 44CAS: 1883548-84-2 Fórmula: C34H28N4O2•HCl Peso molecular: 561.07● Em estoque — Armazém nos EUA, envio para a EU* Item #: A286749Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 4-[2-amino-4-methyl-3-(2-methylquinolin-6-yl)benzoyl]-1-methyl-2,5-diphenylpyrazol-3-one;hydrochloride
- SMILES
- CC1=C(C(=C(C=C1)C(=O)C2=C(N(N(C2=O)C3=CC=CC=C3)C)C4=CC=CC=C4)N)C5=CC6=C(C=C5)N=C(C=C6)C.Cl
- InChIKey
- RNAKBTDDCHJCMT-UHFFFAOYSA-N
- InChI
- show more
- Sinónimos
- 4-[2-Amino-4-methyl-3-(2-methyl-6-quinolinyl)benzoyl]-1,2-dihydro-1-methyl-2,5-diphenyl-3H-pyrazol-3-one hydrochloride
- NSC 295642CAS: 77111-29-6 Fórmula: C15H14ClCuN3S2 Peso molecular: 399.42◐ .Sob encomenda · 8–12 semanas Item #: N352361Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- (E)-benzylsulfanyl-[(E)-1-pyridin-2-ylethylidenehydrazinylidene]-sulfidomethane;chlorocopper(1+)
- SMILES
- CC(=NN=C([S-])SCC1=CC=CC=C1)C2=CC=CC=N2.Cl[Cu+]
- InChIKey
- MGXCRQNCPJBYKM-CWQUOYFRSA-L
- InChI
- 1S/C15H15N3S2.ClH.Cu/c1-12(14-9-5-6-10-16-14)17-18-15(19)20-11-13-7-3-2-4-8-13;;/h2-10H,11H2,1H3,(H,18,19);1H;/q;;+2/p-2/b17-12+;;
- Sinónimos
- (E)-benzylsulfanyl-[(E)-1-pyridin-2-ylethylidenehydrazinylidene]-sulfidomethane;chlorocopper(1+) | DTXSID20444568 | N...
- ISRIB (trans-isomer)CAS: 1597403-47-8 Fórmula: C22H24Cl2N2O4 Peso molecular: 451.34● Em estoque — Armazém nos EUA, envio para a EU* Item #: I275318Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 2-(4-chlorophenoxy)-N-[4-[[2-(4-chlorophenoxy)acetyl]amino]cyclohexyl]acetamide
- SMILES
- C1CC(CCC1NC(=O)COC2=CC=C(C=C2)Cl)NC(=O)COC3=CC=C(C=C3)Cl
- InChIKey
- HJGMCDHQPXTGAV-UHFFFAOYSA-N
- InChI
- show more
- Sinónimos
- ISRIB | ISRIB trans-isomer | BCP23947 | ISRIB, >=98% (HPLC) | N,N'-(Cyclohexane-1,4-diyl)bis(2-(4-chlorophenoxy)aceta...
- S-(Carboxymethyl)-L-cysteine● Em estoque — Armazém nos EUA, envio para a EU* Item #: S161422Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- (2R)-2-amino-3-(carboxymethylsulfanyl)propanoic acid
- SMILES
- N[C@@H](CSCC(O)=O)C(O)=O
- InChIKey
- GBFLZEXEOZUWRN-VKHMYHEASA-N
- InChI
- 1S/C5H9NO4S/c6-3(5(9)10)1-11-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
- Sinónimos
- Carbocysteine, L Isomer | Chilvax | Mucodyne | (2R)-2-amino-3-(carboxymethylsulfanyl)propanoic acid | (2R)-2-amino-3-...
- WKYMVmCAS: 187986-17-0 Fórmula: C41H61N9O7S2 Peso molecular: 856.11● Em estoque — Armazém nos EUA, envio para a EU* Item #: W275202Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Sinónimos
- Leukocyte chemoattractant peptide
- Obestatin human(trifluoroacetate salt)CAS: 1081110-72-6 PubChem CID: 146156385 Fórmula: C116H176N32O33（free basis） Peso molecular: 2546.86（free basis）● Em estoque — Armazém nos EUA, envio para a EU* Item #: O287703Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
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- SMILES
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- InChIKey
- IXQOGPZNKNSCJR-UHFFFAOYSA-N
- InChI
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- GSK2656157, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 3CAS: 1337532-29-2 Fórmula: C23H21FN6O Peso molecular: 416.45Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● Em estoque — Armazém nos EUA, envio para a EU* Item #: G421276Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-(6-methylpyridin-2-yl)ethanone
- SMILES
- CC1=NC(=CC=C1)CC(=O)N2CCC3=C2C=CC(=C3F)C4=CN(C5=NC=NC(=C45)N)C
- InChIKey
- PRWSIEBRGXYXAJ-UHFFFAOYSA-N
- InChI
- show more
- Sinónimos
- 1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydro-1H-indol-1-yl]-2-(6-methyl-2-pyridinyl)e...
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Perguntas frequentes
How is the PERK listing put together?
It draws on reported PERK annotations within Cell Cycle/DNA Damage and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a PERK modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the PERK entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for PERK compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For PERK work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the PERK compound I need is not listed?
Search by CAS number or SMILES first, since analogs of PERK compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.