Fator de Iniciação Eucariótico (eIF)

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  1. Rocaglamide(Roc-A)
    CAS: 84573-16-0 PubChem CID: 331783 Fórmula: C29H31NO7 Peso molecular: 505.57
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Sob encomenda · 8–12 semanas Item #: R276055
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    Nome IUPAC
    (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide
    SMILES
    CN(C)C(=O)C1C(C2(C(C1O)(C3=C(O2)C=C(C=C3OC)OC)O)C4=CC=C(C=C4)OC)C5=CC=CC=C5
    InChIKey
    DAPAQENNNINUPW-IDAMAFBJSA-N
    InChI
    1S/C29H31NO7/c1-30(2)27(32)23-24(17-9-7-6-8-10-17)29(18-11-13-19(34-3)14-12-18)28(33,26(23)31)25-21(36-5)15-20(35-4)16-22(25)37-29/h6-16,23-24,26,31,3show more
    Sinónimos
    FRG4N852F7 | B603847K064 | NSC326408 | Rocaglamide | 1H-Cyclopenta(b)benzofuran-2-carboxamide, 2,3,3a,8b-tetrahydro-1...
  2. ATP-gama-S
    CAS: 93839-89-5 Número CE: 298-862-8 Fórmula: C10H12Li4N5O12P3S Peso molecular: 546.98
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: A274887
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    Nome IUPAC
    tetralithium;[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] dioxidophosphinothioyl phosphate
    SMILES
    [Li+].[Li+].[Li+].[Li+].C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=S)([O-])[O-])O)O)N
    InChIKey
    DWQFDOIBOYDYKH-KWIZKVQNSA-J
    InChI
    1S/C10H16N5O12P3S.4Li/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(25-10)1-24-28(18,19)26-29(20,21)27-30(22,23)31;;;;/h2-4,6-7,10,16-17H,1H2,(H,18,19)show more
    Sinónimos
    Adenosine 5'-(γ-thio)-triphosphate (lithium salt) | P'-anhydride with phosphorothioic acid adenosine 5'-(trihydrogen ...
  3. 6-Methyl-1H-indole-2-carboxylic acid
    CAS: 18474-59-4 Fórmula: C10H9NO2 Peso molecular: 175.18
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: M182288
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    Nome IUPAC
    6-methyl-1H-indole-2-carboxylic acid
    SMILES
    CC1=CC2=C(C=C1)C=C(N2)C(=O)O
    InChIKey
    ZKGSVVHFMZASJS-UHFFFAOYSA-N
    InChI
    1S/C10H9NO2/c1-6-2-3-7-5-9(10(12)13)11-8(7)4-6/h2-5,11H,1H3,(H,12,13)
    Sinónimos
    BDBM50305666 | 6-Methyl-1H-indole-2-carboxylic acid, AldrichCPR | MFCD02664477 | EN300-15104 | NCGC00337851-01 | ZKGS...
  4. 2-((5-(((9H-Fluoren-9-ylmethoxy)carbonyl)amino)-10,11-dihydro-5H-dibenzo(a,d)cyclohepten-2-yl)oxy)acetic acid
    CAS: 212783-75-0 Fórmula: C32H27NO5 Peso molecular: 505.56
    Solid ≥98%
    ◐ .Sob encomenda · 8–12 semanas Item #: S117934
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    2-[[2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-tricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,11,13-hexaenyl]oxy]acetic acid
    SMILES
    C1CC2=C(C=CC(=C2)OCC(=O)O)C(C3=CC=CC=C31)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46
    InChIKey
    XHOBPBDZGGKEOX-UHFFFAOYSA-N
    InChI
    1S/C32H27NO5/c34-30(35)19-37-22-15-16-24-21(17-22)14-13-20-7-1-2-8-23(20)31(24)33-32(36)38-18-29-27-11-5-3-9-25(27)26-10-4-6-12-28(26)29/h1-12,15-17,2show more
    Sinónimos
    AC-32003 | SCHEMBL22572694 | MFCD07783960 | J-013969 | BCP16052 | FT-0643964 | 2-[[5-[[(9H-Fluoren-9-ylmethoxy)carbon...
  5. 4E1RCat
    CAS: 328998-25-0 Fórmula: C28H18N2O6 Peso molecular: 478.45
    10mM in DMSO
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: E423360
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    Nome IUPAC
    4-[(3Z)-3-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenylpyrrol-1-yl]benzoic acid
    SMILES
    C1=CC=C(C=C1)C2=CC(=CC3=CC=C(O3)C4=CC=C(C=C4)[N+](=O)[O-])C(=O)N2C5=CC=C(C=C5)C(=O)O
    InChIKey
    BBQRBOIMSKMFFO-PGMHBOJBSA-N
    InChI
    1S/C28H18N2O6/c31-27-21(16-24-14-15-26(36-24)19-6-12-23(13-7-19)30(34)35)17-25(18-4-2-1-3-5-18)29(27)22-10-8-20(9-11-22)28(32)33/h1-17H,(H,32,33)/b21-show more
    Sinónimos
    4-[(3E)-3-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenylpyrrol-1-yl]benzoic acid
  6. 4E1RCat
    CAS: 328998-25-0 Fórmula: C28H18N2O6 Peso molecular: 478.45
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: E345401
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    Nome IUPAC
    4-[(3Z)-3-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenylpyrrol-1-yl]benzoic acid
    SMILES
    C1=CC=C(C=C1)C2=CC(=CC3=CC=C(O3)C4=CC=C(C=C4)[N+](=O)[O-])C(=O)N2C5=CC=C(C=C5)C(=O)O
    InChIKey
    BBQRBOIMSKMFFO-PGMHBOJBSA-N
    InChI
    1S/C28H18N2O6/c31-27-21(16-24-14-15-26(36-24)19-6-12-23(13-7-19)30(34)35)17-25(18-4-2-1-3-5-18)29(27)22-10-8-20(9-11-22)28(32)33/h1-17H,(H,32,33)/b21-show more
    Sinónimos
    4-[(3E)-3-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenylpyrrol-1-yl]benzoic acid
  7. 4E2RCat
    CAS: 432499-63-3 PubChem CID: 2287236 Fórmula: C22H14ClNO4S2 Peso molecular: 455.93
    ≥98% mixture of isomers
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: E412440
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    Nome IUPAC
    5-[5-[(Z)-(3-benzyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl]-2-chlorobenzoic acid
    SMILES
    C1=CC=C(C=C1)CN2C(=O)C(=CC3=CC=C(O3)C4=CC(=C(C=C4)Cl)C(=O)O)SC2=S
    InChIKey
    WOBPZFKXPCYOLU-ODLFYWEKSA-N
    InChI
    1S/C22H14ClNO4S2/c23-17-8-6-14(10-16(17)21(26)27)18-9-7-15(28-18)11-19-20(25)24(22(29)30-19)12-13-4-2-1-3-5-13/h1-11H,12H2,(H,26,27)/b19-11-
    Sinónimos
    PD103111 | BS-51906 | 5-[5-[(Z)-(3-benzyl-4-oxo-2-thioxo-thiazolidin-5-ylidene)methyl]-2-furyl]-2-chloro-benzoic acid...
  8. Briciclib, G1/S-specific cyclin D1 inhibitor
    CAS: 865783-99-9 PubChem CID: 11248490 Fórmula: C19H23O10PS Peso molecular: 474.42
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: B413506
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    Nome IUPAC
    [2-methoxy-5-[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonylmethyl]phenyl] dihydrogen phosphate
    SMILES
    COC1=C(C=C(C=C1)CS(=O)(=O)C=CC2=C(C=C(C=C2OC)OC)OC)OP(=O)(O)O
    InChIKey
    LXENKEWVEVKKGV-BQYQJAHWSA-N
    InChI
    1S/C19H23O10PS/c1-25-14-10-17(27-3)15(18(11-14)28-4)7-8-31(23,24)12-13-5-6-16(26-2)19(9-13)29-30(20,21)22/h5-11H,12H2,1-4H3,(H2,20,21,22)/b8-7+
    Sinónimos
    AC-36098 | s6533 | 2-Methoxy-5-(((2-(2,4,6-trimethoxyphenyl)ethenyl)sulfonyl)methyl)phenyl dihydrogen phosphate | Bri...
  9. Briciclib, G1/S-specific cyclin D1 inhibitor
    CAS: 865783-99-9 PubChem CID: 11248490 Fórmula: C19H23O10PS Peso molecular: 474.42
    10mM in DMSO
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: B426444
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    Nome IUPAC
    [2-methoxy-5-[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonylmethyl]phenyl] dihydrogen phosphate
    SMILES
    COC1=C(C=C(C=C1)CS(=O)(=O)C=CC2=C(C=C(C=C2OC)OC)OC)OP(=O)(O)O
    InChIKey
    LXENKEWVEVKKGV-BQYQJAHWSA-N
    InChI
    1S/C19H23O10PS/c1-25-14-10-17(27-3)15(18(11-14)28-4)7-8-31(23,24)12-13-5-6-16(26-2)19(9-13)29-30(20,21)22/h5-11H,12H2,1-4H3,(H2,20,21,22)/b8-7+
    Sinónimos
    AC-36098 | s6533 | 2-Methoxy-5-(((2-(2,4,6-trimethoxyphenyl)ethenyl)sulfonyl)methyl)phenyl dihydrogen phosphate | Bri...
  10. Episilvestrol
    CAS: 697235-39-5 Fórmula: C34H38O13 Peso molecular: 654.66
    ◐ .Sob encomenda · 8–12 semanas Item #: E126128
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    Nome IUPAC
    methyl (1R,2R,3S,3aR,8bS)-6-[[(2S,3R,6R)-6-[(1S)-1,2-dihydroxyethyl]-3-methoxy-1,4-dioxan-2-yl]oxy]-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phshow more
    SMILES
    COC1C(OC(CO1)C(CO)O)OC2=CC3=C(C(=C2)OC)C4(C(C(C(C4(O3)C5=CC=C(C=C5)OC)C6=CC=CC=C6)C(=O)OC)O)O
    InChIKey
    GVKXFVCXBFGBCD-JRPGFILLSA-N
    InChI
    1S/C34H38O13/c1-40-20-12-10-19(11-13-20)34-27(18-8-6-5-7-9-18)26(30(38)42-3)29(37)33(34,39)28-23(41-2)14-21(15-24(28)47-34)45-32-31(43-4)44-17-25(46-3show more
    Sinónimos
    DTXSID80466766 | CHEBI:66485 | Episilvestrol | epi-silvestrol | EX-A4881 | MS-30981 | HY-15359 | methyl (1R,2R,3S,3aR...
  11. GCN2iB
    CAS: 2183470-12-2 Fórmula: C18H12ClF2N5O3S Peso molecular: 451.83
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: G414275
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    Nome IUPAC
    N-[3-[2-(2-aminopyrimidin-5-yl)ethynyl]-2,4-difluorophenyl]-5-chloro-2-methoxypyridine-3-sulfonamide
    SMILES
    COC1=C(C=C(C=N1)Cl)S(=O)(=O)NC2=C(C(=C(C=C2)F)C#CC3=CN=C(N=C3)N)F
    InChIKey
    JGHVXJKGYJYWOP-UHFFFAOYSA-N
    InChI
    1S/C18H12ClF2N5O3S/c1-29-17-15(6-11(19)9-23-17)30(27,28)26-14-5-4-13(20)12(16(14)21)3-2-10-7-24-18(22)25-8-10/h4-9,26H,1H3,(H2,22,24,25)
    Sinónimos
    N-[3-[2-(2-Amino-5-pyrimidinyl)ethynyl]-2,4-difluorophenyl]-5-chloro-2-methoxy- 3-pyridinesulfonamide
  12. GCN2iB
    CAS: 2183470-12-2 Fórmula: C18H12ClF2N5O3S Peso molecular: 451.83
    10mM in DMSO
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: G422624
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    Nome IUPAC
    N-[3-[2-(2-aminopyrimidin-5-yl)ethynyl]-2,4-difluorophenyl]-5-chloro-2-methoxypyridine-3-sulfonamide
    SMILES
    COC1=C(C=C(C=N1)Cl)S(=O)(=O)NC2=C(C(=C(C=C2)F)C#CC3=CN=C(N=C3)N)F
    InChIKey
    JGHVXJKGYJYWOP-UHFFFAOYSA-N
    InChI
    1S/C18H12ClF2N5O3S/c1-29-17-15(6-11(19)9-23-17)30(27,28)26-14-5-4-13(20)12(16(14)21)3-2-10-7-24-18(22)25-8-10/h4-9,26H,1H3,(H2,22,24,25)
    Sinónimos
    3-​Pyridinesulfonamide,N-​[3-​[2-​(2-​amino-​5-​pyrimidinyl)​ethynyl]​-​2,​4-​difluorophenyl]​-​5-​chloro-​2-​methoxy-
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Perguntas frequentes

What can I find under Eukaryotic Initiation Factor (eIF)?
This listing collects compounds associated with Eukaryotic Initiation Factor (eIF) within our Cell Cycle/DNA Damage area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for Eukaryotic Initiation Factor (eIF)?
Consider the reported potency of each Eukaryotic Initiation Factor (eIF) compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for Eukaryotic Initiation Factor (eIF) compounds?
Each Eukaryotic Initiation Factor (eIF) product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Eukaryotic Initiation Factor (eIF) compounds by activity or structure?
Yes. Filter the Eukaryotic Initiation Factor (eIF) listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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