Recombinase induzível 1
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57 produtos
Produtos populares
- 6-Bromo-2-hydroxy-3-methoxybenzaldehyde● Em estoque — Armazém nos EUA, envio para a EU* Item #: B153189Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 6-bromo-2-hydroxy-3-methoxybenzaldehyde
- SMILES
- COC1=C(C(=C(C=C1)Br)C=O)O
- InChIKey
- JUPJZUTYDWXZAQ-UHFFFAOYSA-N
- InChI
- 1S/C8H7BrO3/c1-12-7-3-2-6(9)5(4-10)8(7)11/h2-4,11H,1H3
- Sinónimos
- EN300-6498200 | J-012961 | SCHEMBL424251 | 6-Bromo-2-hydroxy-3-methoxybenzaldehyde, 98% | FT-0637938 | J-510172 | DS-...
- APY 29CAS: 1216665-49-4 Fórmula: C17H16N8 Peso molecular: 332.36● Em estoque — Armazém nos EUA, envio para a EU* Item #: A288548Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 2-N-(3H-benzimidazol-5-yl)-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
- SMILES
- C1CC1C2=CC(=NN2)NC3=NC(=NC=C3)NC4=CC5=C(C=C4)N=CN5
- InChIKey
- WJNBSTLIALIIEW-UHFFFAOYSA-N
- InChI
- 1S/C17H16N8/c1-2-10(1)13-8-16(25-24-13)22-15-5-6-18-17(23-15)21-11-3-4-12-14(7-11)20-9-19-12/h3-10H,1-2H2,(H,19,20)(H3,18,21,22,23,24,25)
- Sinónimos
- (E)-N-(6-((5-cyclopropyl-1H-pyrazol-3-yl)imino)-1,6-dihydropyrimidin-2-yl)-1H-benzo[d]imidazol-6-amine | N2-1H-Benzim...
- Diphenylcyclopropenone(DPC)Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● Em estoque — Armazém nos EUA, envio para a EU* Item #: A115107Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 2,3-diphenylcycloprop-2-en-1-one
- SMILES
- C1=CC=C(C=C1)C2=C(C2=O)C3=CC=CC=C3
- InChIKey
- HCIBTBXNLVOFER-UHFFFAOYSA-N
- InChI
- 1S/C15H10O/c16-15-13(11-7-3-1-4-8-11)14(15)12-9-5-2-6-10-12/h1-10H
- Sinónimos
- DPC | Cyclopropenone, 2,3-diphenyl- | NCGC00166113-01 | SR-01000644630-1 | AMY1261 | DIPHENCYPRONE [MI] | DIPHENYLCYC...
- B I09CAS: 1607803-67-7 Fórmula: C16H17NO5 Peso molecular: 303.31◐ .Sob encomenda · 8–12 semanas Item #: B287381Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 7-(1,3-dioxan-2-yl)-8-hydroxy-1,2,3,4-tetrahydrochromeno[3,4-c]pyridin-5-one
- SMILES
- C1COC(OC1)C2=C(C=CC3=C2OC(=O)C4=C3CCNC4)O
- InChIKey
- UYYMWNUDIOPESF-UHFFFAOYSA-N
- InChI
- 1S/C16H17NO5/c18-12-3-2-10-9-4-5-17-8-11(9)15(19)22-14(10)13(12)16-20-6-1-7-21-16/h2-3,16-18H,1,4-8H2
- Sinónimos
- 7-(1,3-Dioxan-2-yl)-1,2,3,4-tetrahydro-8-hydroxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one
- Sunitinib Malate, Tyrosine-protein kinase receptor RET inhibitor● Em estoque — Armazém nos EUA, envio para a EU* Item #: E129728Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide;(2S)-2-hydroxybutanedioic acid
- SMILES
- CCN(CC)CCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)F)NC2=O)C.C(C(C(=O)O)O)C(=O)O
- InChIKey
- LBWFXVZLPYTWQI-IPOVEDGCSA-N
- InChI
- show more
- Sinónimos
- 1H-Pyrrole-3-carboxamide, N-(2-(diethylamino)ethyl)-5-((Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4...
- Sunitinib, Inhibitor of fibroblast growth factor receptor 1;Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of fms related receptor tyrosine kinase 4;Inhibitor of kinase insert domain receptor;Inhibitor of KIT proto-oncogene; receptor tyrosine kinase;ICAS: 557795-19-4 Número CE: 111-194-2 PubChem CID: 5329102 Fórmula: C22H27FN4O2 Peso molecular: 398.47Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● Em estoque — Armazém nos EUA, envio para a EU* Item #: S126061Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
- SMILES
- CCN(CC)CCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)F)NC2=O)C
- InChIKey
- WINHZLLDWRZWRT-ATVHPVEESA-N
- InChI
- show more
- Sinónimos
- 1H-Pyrrole-3-carboxamide,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl- | D08552 | C22H27FN4O2 | N-(2-(Diet...
- Toyocamicina● Em estoque — Armazém nos EUA, envio para a EU* Item #: T275971Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 4-amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile
- SMILES
- C1=C(C2=C(N=CN=C2N1C3C(C(C(O3)CO)O)O)N)C#N
- InChIKey
- XOKJUSAYZUAMGJ-WOUKDFQISA-N
- InChI
- 1S/C12H13N5O4/c13-1-5-2-17(11-7(5)10(14)15-4-16-11)12-9(20)8(19)6(3-18)21-12/h2,4,6,8-9,12,18-20H,3H2,(H2,14,15,16)/t6-,8-,9-,12-/m1/s1
- Sinónimos
- L7995C4D7F | 4-Amino-7-.beta.-D-ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-5-carbonitrile | NSC-99843 | Antibiotic E21...
- 4μ8C● Em estoque — Armazém nos EUA, envio para a EU* Item #: C167186Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 7-hydroxy-4-methyl-2-oxochromene-8-carbaldehyde
- SMILES
- CC1=CC(=O)OC2=C1C=CC(=C2C=O)O
- InChIKey
- RTHHSXOVIJWFQP-UHFFFAOYSA-N
- InChI
- 1S/C11H8O4/c1-6-4-10(14)15-11-7(6)2-3-9(13)8(11)5-12/h2-5,13H,1H3
- Sinónimos
- IRE1 Inhibitor III | BB 0256929 | HMS3653K06 | 4?8C | F2158-2222 | 8-formyl-7-hydroxy-4-methylcoumarin | IRE1 Inhibit...
- 4μ8C10mM in DMSO● Em estoque — Armazém nos EUA, envio para a EU* Item #: C421493Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 7-hydroxy-4-methyl-2-oxochromene-8-carbaldehyde
- SMILES
- CC1=CC(=O)OC2=C1C=CC(=C2C=O)O
- InChIKey
- RTHHSXOVIJWFQP-UHFFFAOYSA-N
- InChI
- 1S/C11H8O4/c1-6-4-10(14)15-11-7(6)2-3-9(13)8(11)5-12/h2-5,13H,1H3
- Sinónimos
- BB 0256929 | HMS3653K06 | 4?8C | F2158-2222 | 8-formyl-7-hydroxy-4-methylcoumarin | IRE1 Inhibitor III | J-007348 | S...
- 6-Bromo-2-hydroxy-3-methoxybenzaldehyde10mM in DMSO● Em estoque — Armazém nos EUA, envio para a EU* Item #: B422438Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 6-bromo-2-hydroxy-3-methoxybenzaldehyde
- SMILES
- COC1=C(C(=C(C=C1)Br)C=O)O
- InChIKey
- JUPJZUTYDWXZAQ-UHFFFAOYSA-N
- InChI
- 1S/C8H7BrO3/c1-12-7-3-2-6(9)5(4-10)8(7)11/h2-4,11H,1H3
- Sinónimos
- EN300-6498200 | J-012961 | SCHEMBL424251 | 6-Bromo-2-hydroxy-3-methoxybenzaldehyde, 98% | FT-0637938 | J-510172 | DS-...
- AMG 18 hydrochloride● Em estoque — Armazém nos EUA, envio para a EU* Item #: A288841Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 2-chloro-N-[6-methyl-5-[3-[2-[[(3S)-piperidin-3-yl]amino]pyrimidin-4-yl]pyridin-2-yl]oxynaphthalen-1-yl]benzenesulfonamide;hydrochloride
- SMILES
- CC1=C(C2=C(C=C1)C(=CC=C2)NS(=O)(=O)C3=CC=CC=C3Cl)OC4=C(C=CC=N4)C5=NC(=NC=C5)NC6CCCNC6.Cl
- InChIKey
- CNWIPRHGMZTPSB-BOXHHOBZSA-N
- InChI
- show more
- Sinónimos
- 2-Chloro-N-[6-methyl-5-[[3-[2-[(3S)-3-piperidinylamino]-4-pyrimidinyl]-2-pyridinyl]oxy]-1-naphthalenyl]benzenesulfona...
- APY 29CAS: 1216665-49-4 Fórmula: C17H16N8 Peso molecular: 332.3610mM in DMSO● Em estoque — Armazém nos EUA, envio para a EU* Item #: A420934Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 2-N-(3H-benzimidazol-5-yl)-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
- SMILES
- C1CC1C2=CC(=NN2)NC3=NC(=NC=C3)NC4=CC5=C(C=C4)N=CN5
- InChIKey
- WJNBSTLIALIIEW-UHFFFAOYSA-N
- InChI
- 1S/C17H16N8/c1-2-10(1)13-8-16(25-24-13)22-15-5-6-18-17(23-15)21-11-3-4-12-14(7-11)20-9-19-12/h3-10H,1-2H2,(H,19,20)(H3,18,21,22,23,24,25)
- Sinónimos
- (E)-N-(6-((5-cyclopropyl-1H-pyrazol-3-yl)imino)-1,6-dihydropyrimidin-2-yl)-1H-benzo[d]imidazol-6-amine;N2-1H-Benzimid...
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Perguntas frequentes
How is the IRE1 listing put together?
It draws on reported IRE1 annotations within Cell Cycle/DNA Damage and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an IRE1 modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the IRE1 entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for IRE1 compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For IRE1 work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the IRE1 compound I need is not listed?
Search by CAS number or SMILES first, since analogs of IRE1 compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.