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GCLC

DescriptionGlutamate--cysteine ligase catalytic subunit

Gene and Protein Information

Gene ID2729
Uniprot Accession IDs P48506 Q14399
Ensembl ID ENSG00000001084
Symbol GLCL GLCLC GCL GCS GLCL GLCLC
FamilyBelongs to the glutamate--cysteine ligase type 3 family.
Sequence
MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDHENKKVRLVLSGEKVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTVEANMRKRRKEATSILEENQALCTITSFPRLGCPGFTLPEVKPNPVEGGASKSLFFPDEAINKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFTEDDEASRASKPDHIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVISASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSKCGEKYNDIDLTIDKEIYEQLLQEGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVLQGMFYFRKDICKGGNAVVDGCGKAQNSTELAAEEYTLMSIDTIINGKEGVFPGLIPILNSYLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNYSLILKCNQIANELCECPELLGSAFRKVKYSGSKTDSSN
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp742732GCLCglutamate-cysteine ligase catalytic subunit9598VGNC:8164OMA, EggNOG
Macaque710508GCLCglutamate-cysteine ligase catalytic subunit9544Inparanoid, OMA, EggNOG
Mouse14629Gclcglutamate-cysteine ligase, catalytic subunit10090MGI:104990Inparanoid, OMA, EggNOG
Rat25283Gclcglutamate-cysteine ligase, catalytic subunit10116RGD:619868Inparanoid, OMA, EggNOG
Dog609822GCLCglutamate-cysteine ligase catalytic subunit9615VGNC:41147Inparanoid, OMA, EggNOG
Horse100056731GCLCglutamate-cysteine ligase catalytic subunit9796VGNC:18277Inparanoid, OMA, EggNOG
Cow512468GCLCglutamate-cysteine ligase catalytic subunit9913VGNC:29289Inparanoid, OMA, EggNOG
Pig100522018GCLCglutamate-cysteine ligase catalytic subunit9823Inparanoid, OMA, EggNOG
Opossum100014379GCLCglutamate-cysteine ligase catalytic subunit13616Inparanoid, OMA, EggNOG
Platypus100078137GCLCglutamate-cysteine ligase catalytic subunit9258Inparanoid, OMA, EggNOG
Chicken421894GCLCglutamate-cysteine ligase catalytic subunit9031CGNC:12202Inparanoid, OMA, EggNOG
Anole lizard100554798gclcglutamate-cysteine ligase catalytic subunit28377Inparanoid, OMA, EggNOG
Xenopus780264gclcglutamate-cysteine ligase, catalytic subunit8364XB-GENE-1002435Inparanoid, OMA, EggNOG
Zebrafish326857gclcglutamate-cysteine ligase, catalytic subunit7955ZDB-GENE-030131-5056Inparanoid, OMA, EggNOG
C. elegans174438gcs-1Glutamate--cysteine ligase6239Inparanoid, OMA
Fruitfly53581GclcGlutamate-cysteine ligase catalytic subunit7227FBgn0040319Inparanoid, EggNOG
S.cerevisiae853344GSH1glutamate--cysteine ligase4932S000003637Inparanoid, OMA, EggNOG

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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