ALLN - ≥95% , CAS No.110044-82-1

CAS: 110044-82-1 Cat. No.: A274819 Peso molecular: 383.54 Número EC: 805-362-0
Disponible para pedir
GRADE & PURITY ≥95%
Synonyms
Calpain inhibitor I;Ac-LLnL-CHO;ALLN | DTXSID70911457 | KBioGR_000279 | MG 101 | 2-[(1-Hydroxyethylidene)amino]-N-{1-hydroxy-4-methyl-1-[(1-oxohexan-2-yl)imino]pentan-2-yl}-4-methylpentanimidic acid | Calpain Inhibitor I, >=97% (TLC), powder | Bio2_000279
Storage
Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
5mg
A274819-5mg
3
107,90US$
10mg
A274819-10mg
3
161,90US$
25mg
A274819-25mg
2
189,90US$
50mg
A274819-50mg
2
315,90US$
100mg
A274819-100mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
474,90US$
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Desiccated Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Product Describtion:

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.


Product Application:
Calpain Inhibitor I have been used: as a component of protease inhibitor cocktail for gel shift analysis for treating HeLa cell cultures for inhibition of 26 S proteasome in 26 S proteasome inhibition assays

Specifications

Sinónimos
Calpain inhibitor I;Ac-LLnL-CHO;ALLN | DTXSID70911457 | KBioGR_000279 | MG 101 | 2-[(1-Hydroxyethylidene)amino]-N-{1-hydroxy-4-methyl-1-[(1-oxohexan-2-yl)imino]pentan-2-yl}-4-methylpentanimidic acid | Calpain Inhibitor I, >=97% (TLC), powder | Bio2_000279
Especificaciones y pureza
≥95%
Mecanismos bioquímicos y fisiológicos
Potent, cell-permeable cysteine proteinase inhibitor (K i values are 190 (calpain I), 220 (calpain II), 150 (cathepsin B) nM and 500 pM (cathepsin L). Promotes Bax-dependent apoptosis in cancer cells. Antitumor agent. Calpain Inhibitor I inhibits tumor ne
Condiciones de almacenamiento de almacenamiento
Store at -20°C, Desiccated
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Nota
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Pureza
≥95%
Nombres e identificadores
Pubchem Sid504758792
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504758792
Sonrisas canónicasCCCCC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C
IUPAC Name(2S)-2-acetamido-4-methyl-N-[(2S)-4-methyl-1-oxo-1-[[(2S)-1-oxohexan-2-yl]amino]pentan-2-yl]pentanamide
InChIKeyFMYKJLXRRQTBOR-BZSNNMDCSA-N
INCHI1S/C20H37N3O4/c1-7-8-9-16(12-24)22-19(26)18(11-14(4)5)23-20(27)17(10-13(2)3)21-15(6)25/h12-14,16-18H,7-11H2,1-6H3,(H,21,25)(H,22,26)(H,23,27)/t16-,17-,18-/m0/s1
Isómeros SMILES CCCC[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)C
Peso molecular 383.54
Reaxy-Rn 10703469
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=10703469&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClaseCarboxylic acids and derivatives
SubclassAmino acids, peptides, and analogues
Intermediate Tree Nodes Peptides
Direct ParentDipeptides
Alternative Parents Leucine and derivatives  N-acyl-alpha amino acids and derivatives  Alpha amino acid amides  N-acyl amines  Acetamides  Secondary carboxylic acid amides  Organopnictogen compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  Aldehydes  
Molecular FrameworkAliphatic acyclic compounds
Substituents Alpha-dipeptide - Leucine or derivatives - N-acyl-alpha amino acid or derivatives - Alpha-amino acid amide - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - Fatty amide - Fatty acyl - N-acyl-amine - Acetamide - Carboxamide group - Secondary carboxylic acid amide - Aldehyde - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Carbonyl group - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Aliphatic acyclic compound
DescripciónThis compound belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond.
External Descriptors tripeptide - aldehyde
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
CTSB Tchem Cathepsin B (3822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PC-3 (62116 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HeLa (62764 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP5 Tchem Ubiquitin carboxyl-terminal hydrolase 5 (172 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CFL1 Tbio Cofilin-1 (12 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SMN1 Tchem Survival motor neuron protein (34246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Cruzipain (33337 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abcb1b P-glycoprotein 1 (174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CAPN1 Calpain 1 (219 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
B16 (5829 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L1210 (27553 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
H4 (48 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeFechaArticulo
C2625076Certificate of AnalysisApr 07, 2026 A274819
C2204068Certificate of AnalysisDec 12, 2025 A274819
C2204087Certificate of AnalysisDec 12, 2025 A274819
C2204101Certificate of AnalysisDec 12, 2025 A274819
C2204164Certificate of AnalysisDec 12, 2025 A274819
C2204165Certificate of AnalysisDec 12, 2025 A274819
Propiedades químicas y físicas
SolubilidadSoluble in DMSO to 50 mM and in ethanol
Peso molecular383.500 g/mol
XLogP33.000
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count13
Exact Mass383.278 Da
Monoisotopic Mass383.278 Da
Topological Polar Surface Area104.000 Ų
Heavy Atom Count27
Formal Charge0
Complexity492.000
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Preguntas frecuentes y artículos
Calculadoras de soluciones
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