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224,000+ productos de investigación · Triple ISO certified · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items
Why this grade
Moligand™,≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Elesclomol (STA-4783) is a novel potent oxidative stress inducer that elicits pro-apoptosis events among tumor cells. Phase 3.
Specifications
Sinónimos
STA-4783
Especificaciones y pureza
Moligand™, ≥98%
Mecanismos bioquímicos y fisiológicos
Elesclomol significantly induces the expression of heat shock stress response genes and metallothionein genes, a signature transcription profile indicative of oxidative stress in Hs294T cells。Elesclomol significantly inhibits the cell viability of SK-MEL-
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
ACTIVATOR
Pureza
≥98%
Nombres e identificadores
| Sonrisas canónicas | CN(C(=S)C1=CC=CC=C1)NC(=O)CC(=O)NN(C)C(=S)C2=CC=CC=C2 |
|---|---|
| IUPAC Name | 1-N',3-N'-bis(benzenecarbonothioyl)-1-N',3-N'-dimethylpropanedihydrazide |
| InChIKey | BKJIXTWSNXCKJH-UHFFFAOYSA-N |
| INCHI | 1S/C19H20N4O2S2/c1-22(18(26)14-9-5-3-6-10-14)20-16(24)13-17(25)21-23(2)19(27)15-11-7-4-8-12-15/h3-12H,13H2,1-2H3,(H,20,24)(H,21,25) |
| Isómeros SMILES | CN(C(=S)C1=CC=CC=C1)NC(=O)CC(=O)NN(C)C(=S)C2=CC=CC=C2 |
| Peso molecular | 400.52 |
| Reaxy-Rn | 11332608 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11332608&ln= |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Taxonomic Classification
Taxonomy Tree
- Kingdom Organic compounds
- Superclass Benzenoids
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Clase | Benzene and substituted derivatives |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Benzene and substituted derivatives |
| Alternative Parents | 1,3-dicarbonyl compounds Thioamides Carboxylic acid hydrazides Thiocarbonyl compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Monocyclic benzene moiety - 1,3-dicarbonyl compound - Thioamide - Carboxylic acid hydrazide - Carboxylic acid derivative - Hydrocarbon derivative - Organopnictogen compound - Thiocarbonyl group - Organic oxygen compound - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Carbonyl group - Organic nitrogen compound - Organic oxide - Aromatic homomonocyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as benzene and substituted derivatives. These are aromatic compounds containing one monocyclic ring system consisting of benzene. |
| External Descriptors | carbohydrazide - thiocarbonyl compound |
Estructura 3D
Modelo de Estructura Química Interactiva
Objetivos asociados (humanos)
5637 (630 Activities)
A 172 (535 Activities)
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A204 (242 Activities)
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A2058 (690 Activities)
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A-375 (9258 Activities)
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A-427 (643 Activities)
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A498 (42825 Activities)
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A673 (619 Activities)
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ACHN (49357 Activities)
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AGS (1999 Activities)
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BT-20 (503 Activities)
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BT-474 (2113 Activities)
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|---|
BXPC-3 (2997 Activities)
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C8166 (1658 Activities)
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CAKI-1 (44928 Activities)
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Calu-3 (339 Activities)
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Calu-6 (398 Activities)
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CAPAN-1 (772 Activities)
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CCRF-CEM (65223 Activities)
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CFPAC-1 (421 Activities)
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COLO 205 (50209 Activities)
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COR-L23 (253 Activities)
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Daoy (570 Activities)
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DMS-79 (150 Activities)
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DMS-273 (14108 Activities)
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DU-145 (51482 Activities)
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G-361 (890 Activities)
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G-401 (156 Activities)
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HL-60 (67320 Activities)
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HT-1080 (3966 Activities)
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HT-29 (80576 Activities)
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HuCCT-1 (128 Activities)
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Huh-7 (12904 Activities)
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HuTu80 (255 Activities)
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J82 (505 Activities)
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JAR (316 Activities)
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K562 (73714 Activities)
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KM12 (47707 Activities)
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LoVo (4724 Activities)
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M14 (47487 Activities)
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MCF7 (126967 Activities)
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MDA-MB-361 (612 Activities)
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MDA-MB-453 (1139 Activities)
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MG-63 (795 Activities)
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NCI-H1975 (4994 Activities)
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MKN-1 (175 Activities)
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MKN-28 (466 Activities)
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MKN-45 (2102 Activities)
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MKN-7 (272 Activities)
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ML-2 (146 Activities)
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Objetivos asociados (no humanos)
Hdac6 Histone deacetylase 6 (222 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mycobacterium tuberculosis (203094 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Canis familiaris (36305 Activities)
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Mus musculus (284745 Activities)
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Rattus norvegicus (775804 Activities)
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H4 (48 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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rep Replicase polyprotein 1ab (378 Activities)
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Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 F2611344 | Certificate of Analysis | May 30, 2026 | E126032 |
| F2611345 | Certificate of Analysis | May 30, 2026 | E126032 |
| F2611346 | Certificate of Analysis | May 30, 2026 | E126032 |
| F2611347 | Certificate of Analysis | May 30, 2026 | E126032 |
| F2611349 | Certificate of Analysis | May 30, 2026 | E126032 |
| L2017180 | Certificate of Analysis | Apr 15, 2026 | E126032 |
| H1624055 | Certificate of Analysis | Nov 06, 2025 | E126032 |
| K2301079 | Certificate of Analysis | Aug 11, 2025 | E126032 |
| A2510120 | Certificate of Analysis | Jan 14, 2025 | E126032 |
Propiedades químicas y físicas
| Solubilidad | DMSO ≥78mg/mL Water <1.2mg/mL Ethanol <1.2mg/mL |
|---|---|
| Peso molecular | 400.500 g/mol |
| XLogP3 | 2.900 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 4 |
| Exact Mass | 400.103 Da |
| Monoisotopic Mass | 400.103 Da |
| Topological Polar Surface Area | 129.000 Ų |
| Heavy Atom Count | 27 |
| Formal Charge | 0 |
| Complexity | 510.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
Preguntas frecuentes y artículos
Metabolic signaling pathway
Categories: Technical articles
Citations of This Product
Referencias
| 1. Hangyi Wu, Zhenhai Zhang, Yanni Cao, Yuhan Hu, Yi Li, Lanyi Zhang, Xinyi Cao, Haitong Wen, Youwen Zhang, Huixia Lv, Xin Jin. (2024) A Self-Amplifying ROS-Responsive Nanoplatform for Simultaneous Cuproptosis and Cancer Immunotherapy. Advanced Science, [PMID:38569217] [10.1002/advs.202401047] |
| 2. Tian Shaoping, Wang Rui, Wang Yiting, Chen Ruibing, Lin Tianyu, Xiao Xuesong, Liu Xinyu, Ideozu Justin Eze, Geng Hua, Wang Yong, Yue Dan. (2024) p32 regulates glycometabolism and TCA cycle to inhibit ccRCC progression via copper-induced DLAT lipoylation oligomerization. International Journal of Biological Sciences, 20 (2): (516-536). [PMID:38169635] [10.7150/ijbs.84399] |
Calculadoras de soluciones
Reseñas
Reseñas de cliente
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