1,700+ technical articles by Aladdin Scientific's scientists on reagent selection, reaction mechanisms, assay design and formulation. New every week.
Microbial strains are one of the most fundamental and critical biological resources in a lab; preservation quality directly affects the reliability and reproducibility of downstream experiments. Different preservation strategies vary markedly in survival duration, genetic stability, operational ...
GelRed is a commonly used nucleic acid fluorescent dye for detecting DNA in agarose gel electrophoresis. Compared with ethidium bromide (EtBr), GelRed offers higher safety and greater detection sensitivity and can be imaged with EtBr filter sets.
Human diseases number in the tens of thousands, yet only a fraction have effective treatments—and even fewer can be called “curable.” In many cases, current therapies primarily relieve symptoms or slow progression rather than addressing root causes. In recent years, as CRISPR gene-editing ...
In handling cell and tissue samples, choosing a lysis buffer is not just about “breaking cells open”—it determines whether proteins are detectable, remain active, and retain complexes and post-translational modifications. Different systems vary greatly in strength, denaturation, and ...
The streptavidin–biotin system has extremely high affinity and is one of the most commonly used tool pairs for immobilization, capture, and elution of nucleic acids and proteins.
In molecular biology and cell engineering experiments, introducing exogenous nucleic acids into cells is one of the most basic and commonly used operations. Depending on the recipient cell type and the genetic outcome, this process is typically called transfection or transformation. The two are ...
After proteins are separated by SDS-PAGE or related gels, staining is used for visualization, rough quantification, and purity assessment.
The streptavidin–biotin system is one of the most widely used high-affinity ligand–receptor pairs in biochemistry and molecular biology.
The 2022 Nobel Prize in Chemistry was awarded to American scientists Carolyn R. Bertozzi, K. Barry Sharpless, and Danish scientist Morten Meldal in recognition of their contributions to the development of click chemistry and bioorthogonal chemistry. These three scientists pioneered a brand-new ...