Ciclo celular/Daño en el ADN - Pequeñito Supplier | High Purity

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Griseofulvin, Tubulin inhibitor
CAS: 126-07-8 Número EC: 204-767-4 Fórmula: C₁₇H₁₇ClO₆ Peso molecular: 352.77

Analytical standard ?

● En stock — EE. UU. Articulo #: G101269
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Nombre IUPAC

(2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione

SMILES

CC1CC(=O)C=C(C12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC

InChIKey
DDUHZTYCFQRHIY-RBHXEPJQSA-N

InChI

1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1

Sinónimos
CCRIS 320 | Grifulin | (2S-trans)-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2(3H),1'-(2)cyclohexene)-3,4'-...
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MK-1775, Serine/threonine-protein kinase WEE1 inhibitor
CAS: 955365-80-7 Número EC: 680-342-0 Fórmula: C₂₇H₃₂N₈O₂ Peso molecular: 500.61

Moligand™ ? ≥98%

● En stock — EE. UU. Articulo #: M127160
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Nombre IUPAC

1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one

SMILES

CC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC=C(C=C4)N5CCN(CC5)C)O

InChIKey
BKWJAKQVGHWELA-UHFFFAOYSA-N

InChI

1S/C27H32N8O2/c1-5-13-34-25(36)21-18-28-26(29-19-9-11-20(12-10-19)33-16-14-32(4)15-17-33)31-24(21)35(34)23-8-6-7-22(30-23)27(2,3)37/h5-12,18,37H,1,13-show more

Sinónimos
MK-1775(AZD-1775,Adavosertib) | 2-allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenyla...
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Griseofulvin
CAS: 126-07-8 Número EC: 204-767-4 Fórmula: C₁₇H₁₇ClO₆ Peso molecular: 352.77

Solid ≥97%

● En stock — EE. UU. Articulo #: G101270
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Nombre IUPAC

(2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione

SMILES

CC1CC(=O)C=C(C12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC

InChIKey
DDUHZTYCFQRHIY-RBHXEPJQSA-N

InChI

1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1

Sinónimos
Grisovin | Curling factor | Fulcin | Likuden | Grizeofulvin | Griseofulvina | Grifulvin | Grysio | Delmofulvina | Gri...
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PD0166285, Inhibitor of epidermal growth factor receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of platelet derived growth factor receptor beta;Inhibitor of protein kinase; membrane associated tyrosine/threonine 1;Inhibitor of SRC proto-oncogene;
CAS: 185039-89-8 PubChem CID: 5311382 Fórmula: C₂₆H₂₇Cl₂N₅O₂ Peso molecular: 512.43

Moligand™ ? ≥99%

● En stock — EE. UU. Articulo #: P276244
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Nombre IUPAC

6-(2,6-dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one

SMILES

CCN(CC)CCOC1=CC=C(C=C1)NC2=NC=C3C=C(C(=O)N(C3=N2)C)C4=C(C=CC=C4Cl)Cl

InChIKey
IFPPYSWJNWHOLQ-UHFFFAOYSA-N

InChI

1S/C26H27Cl2N5O2/c1-4-33(5-2)13-14-35-19-11-9-18(10-12-19)30-26-29-16-17-15-20(25(34)32(3)24(17)31-26)23-21(27)7-6-8-22(23)28/h6-12,15-16H,4-5,13-14H2show more

Sinónimos
AKOS022190406 | SCHEMBL133914 | Kinome_3263 | BCP20228 | EX-A4179 | 6-(2,6-Dichloro-phenyl)-2-[4-(2-diethylamino-etho...
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Bosutinib Isomer 1, Free Base
CAS: 1391063-17-4 PubChem CID: 5328940 Fórmula: C26H29Cl2N5O3 Peso molecular: 530.45

◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: B330520
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Sinónimos
Bosutinib,SKI-606 | BSPBio_001023 | NCGC00241107-03 | NSC799367 | NSC-799367 | 4-(2,4-Dichloro-5-methoxy-phenylamino)...
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Griseofulvin, Tubulin inhibitor
CAS: 126-07-8 Número EC: 204-767-4 Fórmula: C₁₇H₁₇ClO₆ Peso molecular: 352.77

Liquid 10mM in DMSO

● En stock — EE. UU. Articulo #: G421095
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Nombre IUPAC

(2S,5'R)-7-chloro-3',4,6-trimethoxy-5'-methylspiro[1-benzofuran-2,4'-cyclohex-2-ene]-1',3-dione

SMILES

CC1CC(=O)C=C(C12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC

InChIKey
DDUHZTYCFQRHIY-RBHXEPJQSA-N

InChI

1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1

Sinónimos
griseofulvin|126-07-8|Amudane|(+)-Griseofulvin|Griseofulvinum|Grisactin|Grifulvin|Grisefuline|Griseofulvina|Grisofulv...
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PD0166285, Inhibitor of epidermal growth factor receptor;Inhibitor of fibroblast growth factor receptor 1;Inhibitor of platelet derived growth factor receptor beta;Inhibitor of protein kinase; membrane associated tyrosine/threonine 1;Inhibitor of SRC proto-oncogene;
CAS: 185039-89-8 PubChem CID: 5311382 Fórmula: C₂₆H₂₇Cl₂N₅O₂ Peso molecular: 512.43

Moligand™ ? 10mM in DMSO

● En stock — EE. UU. Articulo #: P422267
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Nombre IUPAC

6-(2,6-dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one

SMILES

CCN(CC)CCOC1=CC=C(C=C1)NC2=NC=C3C=C(C(=O)N(C3=N2)C)C4=C(C=CC=C4Cl)Cl

InChIKey
IFPPYSWJNWHOLQ-UHFFFAOYSA-N

InChI

1S/C26H27Cl2N5O2/c1-4-33(5-2)13-14-35-19-11-9-18(10-12-19)30-26-29-16-17-15-20(25(34)32(3)24(17)31-26)23-21(27)7-6-8-22(23)28/h6-12,15-16H,4-5,13-14H2show more

Sinónimos
AKOS022190406 | SCHEMBL133914 | Kinome_3263 | BCP20228 | EX-A4179 | 6-(2,6-Dichloro-phenyl)-2-[4-(2-diethylamino-etho...
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Wee1 inhibitor
CAS: 622855-37-2 PubChem CID: 10384072 Fórmula: C₂₀H₁₁ClN₂O₃ Peso molecular: 362.77

◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: W342954
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Nombre IUPAC

4-(2-chlorophenyl)-9-hydroxy-6H-pyrrolo[3,4-c]carbazole-1,3-dione

SMILES

C1=CC=C(C(=C1)C2=CC3=C(C4=C(N3)C=CC(=C4)O)C5=C2C(=O)NC5=O)Cl

InChIKey
DPEXRCOBPACFOO-UHFFFAOYSA-N

InChI

1S/C20H11ClN2O3/c21-13-4-2-1-3-10(13)11-8-15-16(18-17(11)19(25)23-20(18)26)12-7-9(24)5-6-14(12)22-15/h1-8,22,24H,(H,23,25,26)

Sinónimos
BDBM50192371 | Wee1 Inhibitor I | Wee1-Inhibitor-I | MS-25768 | HY-108343 | Wee1 Inhibitor-I | SCHEMBL5828030 | Wee1 ...
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Azenosertib (Zn-C3), Inhibitor of WEE1 G2 checkpoint kinase
CAS: 2376146-48-2 Número EC: 189-014-7 PubChem CID: 139467635 Fórmula: C₂₉H₃₄N₈O₂ Peso molecular: 526.63

Moligand™ ? ≥98%

● En stock — EE. UU. Articulo #: A607901
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Nombre IUPAC

1-[(7R)-7-ethyl-7-hydroxy-5,6-dihydrocyclopenta[b]pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one

SMILES

O=c1n(CC=C)n(c2ccc3CC[C@@](CC)(O)c3n2)c2nc(Nc3ccc(N4CCN(C)CC4)cc3)ncc12

InChIKey
OXTSYWDBUVRXFF-GDLZYMKVSA-N

InChI

1S/C29H34N8O2/c1-4-14-36-27(38)23-19-30-28(31-21-7-9-22(10-8-21)35-17-15-34(3)16-18-35)33-26(23)37(36)24-11-6-20-12-13-29(39,5-2)25(20)32-24/h4,6-11,1show more

Sinónimos
compound 16 [PMID: 34423975] | azenosertib | Azenosertib [INN] | EX-A6113 | 9J13XU96Z1 | (R)-2-allyl-1-(7-ethyl-7-hyd...
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WEE1-IN-5
CAS: 2243882-74-6 Fórmula: C₂₆H₂₈Cl₂N₆O Peso molecular: 511.45

≥99%

◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: W648831
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SMILES

O=C1C2=CN=C(NC3=CC=C(C4CCN(CC4)C)C(C)=C3)N=C2N(CN1C5=C(Cl)C=CC=C5Cl)C
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RP-6306
CAS: 2719793-90-3 Fórmula: C₁₈H₂₀N₄O₂ Peso molecular: 324.38

≥99%

◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: R646400
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WEE1-IN-3
CAS: 2272976-28-8 PubChem CID: 137471996 Fórmula: C₂₈H₃₁N₇O₂ Peso molecular: 497.59

≥98%

◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: W648627
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Nombre IUPAC

1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[(2-methylspiro[1,3-dihydroisoquinoline-4,1'-cyclopropane]-7-yl)amino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidishow more

SMILES

CC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC5=C(C=C4)C6(CC6)CN(C5)C)O

InChIKey
JSZFIXAMFNNRKS-UHFFFAOYSA-N

InChI

1S/C28H31N7O2/c1-5-13-34-25(36)20-15-29-26(32-24(20)35(34)23-8-6-7-22(31-23)27(2,3)37)30-19-9-10-21-18(14-19)16-33(4)17-28(21)11-12-28/h5-10,14-15,37Hshow more

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Preguntas frecuentes

How is the Wee1 listing put together?

It draws on reported Wee1 annotations within Cell Cycle/DNA Damage and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.

How do I choose a Wee1 modulator for my assay?

Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Wee1 entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.

Which specifications matter most for Wee1 compounds?

Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Wee1 work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

What if the Wee1 compound I need is not listed?

Search by CAS number or SMILES first, since analogs of Wee1 compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.