CD28

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  1. MDK 24720 (CTLA-4 inhibitor)
    CAS: 635324-72-0 Formula: C21H13F4N5O Peso molecular: 427.35
    En Stock Articulo #: M412249
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    Identificadores técnicos
    Nombre IUPAC
    4-(4-fluorophenyl)-10-methyl-7-[3-(trifluoromethyl)phenyl]-3,4,8,10,11-pentazatricyclo[7.3.0.02,6]dodeca-1,6,8,11-tetraen-5-one
    SMILES
    CN1C2=NC(=C3C(=C2C=N1)NN(C3=O)C4=CC=C(C=C4)F)C5=CC(=CC=C5)C(F)(F)F
    InChIKey
    WQKVVTLTCHDAST-UHFFFAOYSA-N
    InChI
    1S/C21H13F4N5O/c1-29-19-15(10-26-29)18-16(20(31)30(28-18)14-7-5-13(22)6-8-14)17(27-19)11-3-2-4-12(9-11)21(23,24)25/h2-10,28H,1H3
    Sinónimos
    2-(4-Fluorophenyl)-6-methyl-4-(3-(trifluoromethyl)phenyl)-1,2-dihydrodipyrazolo[3,4-b:3',4'-d]pyridin-3(6H)-one | B7/...
  2. Tiragolumab (anti-TIGIT), INHIBITOR of T-cell immunoreceptor with Ig and ITIM domains inhibitor
    CAS: 1918185-84-8
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    En Stock Articulo #: Ab169250
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    Associated targets
    TIGIT
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Especies reactivas
    Cynomolgus monkey, Human, Rabbit
    Isotipo
    Human IgG1
    Especies hospedadoras
    Human
    Conjugación
    Unconjugated
    Sinónimos
    RG6058 | MTIG7192A | T cell immunoreceptor with Ig and ITIM domains | TIGIT | VSIG9 | VSTM3 | WUCAM | DKFZp667A205 an...
  3. Prezalumab (anti-B7-H2)
    CAS: 1523164-68-2
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    En Stock Articulo #: Ab170952
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    Precios y tamaños del paquete
    Identificadores técnicos
    Associated targets
    ICOSLG
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2SA; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Especies reactivas
    Cynomolgus monkey, Human, Mouse
    Isotipo
    Human IgG2SA
    Especies hospedadoras
    Human
    Conjugación
    Unconjugated
    Sinónimos
    B7 H2 antibody | B7 homolog 2 antibody | B7 homologue 2 antibody | B7 like protein Gl50 antibody | B7 related protein...
  4. Galiximab (anti-CD80), INHIBITOR of T-lymphocyte activation antigen CD80 inhibitor
    CAS: 357613-77-5
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    En Stock Articulo #: Ab177850
    Vista del artículo
    Precios y tamaños del paquete
    Identificadores técnicos
    Associated targets
    CD80
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Especies reactivas
    Cynomolgus monkey, Human
    Isotipo
    Human IgG1
    Especies hospedadoras
    Human
    Conjugación
    Unconjugated
    Sinónimos
    Activation B7-1 antigen | B7 | BB1 | CTLA-4 counter-receptor B7.1
  5. CD80-IN-3
    CAS: 486449-65-4 PubChem CID: 644103 Formula: C17H10FN3O3 Peso molecular: 323.28
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Fuera de Stock Articulo #: C651374
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    Identificadores técnicos
    Nombre IUPAC
    4-(6-fluoro-3-oxo-1H-pyrazolo[4,3-c]quinolin-2-yl)benzoic acid
    SMILES
    C1=CC2=C3C(=CN=C2C(=C1)F)C(=O)N(N3)C4=CC=C(C=C4)C(=O)O
    InChIKey
    NLGJRBLPUVEYKC-UHFFFAOYSA-N
    InChI
    1S/C17H10FN3O3/c18-13-3-1-2-11-14-12(8-19-15(11)13)16(22)21(20-14)10-6-4-9(5-7-10)17(23)24/h1-8,20H,(H,23,24)
    Sinónimos
    LBEWFVRAHKOLOU-UHFFFAOYSA-N | CD80-IN-3 | benzoic acid, 4-(6-fluoro-3,5-dihydro-3-oxo-2H-pyrazolo[4,3-c]quinolin-2-yl...
  6. Theralizumab (anti-CD28)
    CAS: 906068-56-2
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    En Stock Articulo #: Ab190136
    Vista del artículo
    Precios y tamaños del paquete
    Identificadores técnicos
    Associated targets
    CD28
    Short Overview
    Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG4; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Especies reactivas
    Human
    Isotipo
    Human IgG4
    Especies hospedadoras
    Human
    Conjugación
    Unconjugated
    SMILES
    [Theralizumab]
    Sinónimos
    CD 28 antibody | CD28 antibody | CD28 antigen antibody | CD28 molecule antibody | CD28_HUMAN antibody | MGC138290 ant...
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