β-Nicotinamide adenine dinucleotide(NAD) - ≥99.5% , CAS No.53-84-9

CAS: 53-84-9 Cat. No.: N1492516 Peso molecular: 663.43 (anhydrous basis) Beilstein Registry Number: 3584133 Número EC: 200-184-4

GRADE & PURITY ≥99.5%

Synonyms

beta-Diphosphopyridine nucleotide | DPN | β-DPN, β-NAD

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Descripción general

​Use NAD, Grade II as a cofactor in a variety of diagnostic tests, such as for the

determination of ethanol and lactate dehydrogenase.

Benefifits

Rely on the proven diagnostic quality of this product.

​Specifification

Appearance: Colorless to slightly yellowish lyophilizate

Solubility: Clear, colorless to slightly yellowish solution in water (c=200 mg/ ml)

β-NAD (from value found enzymatically, based on dry weight): ≥97.5%

β-NAD (enzymatically, A340): ≥94.5%

β-NAD (A260, ε=17.6 [l x mmol-1 x cm-1]): ≥94.5%

NAD (HPLC): ≥95 area%

Water (K. Fischer): ≤3.5%

Fe (AA): ≤25 ppm

AMP (enzymatically): ≤0.1%

Ethanol (GC): ≤40 ppm

Aceton, isopropanol, methanol (GC): ≤0.1%, ≤0.15%, ≤0.15%

Reaction rates (LDH) based on NAD II, acid: 95-105%

A250/A260: 0.81-0.85

A280/A260: 0.20-0.24

Stability: At +2 to +8°C within specifification range for 12 months. Store dry

Specifications

Sinónimos

beta-Diphosphopyridine nucleotide | DPN | β-DPN, β-NAD

Especificaciones y pureza

≥99.5%

Mecanismos bioquímicos y fisiológicos

β-Nicotinamide adenine dinucleotide (β-NAD) is a neuromodulator and an inhibitory neurotransmitter. It is an agonist for purinergic (P2Y1) receptors. β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) compri

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Desiccated

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥99.5%

Nombres e identificadores

• Sonrisas canónicas: C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N
• IUPAC Name: [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
• InChIKey: BAWFJGJZGIEFAR-NNYOXOHSSA-N
• INCHI: 1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
• Isómeros SMILES: C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N
• WGK Alemania: 3
• RTECS: UU3450000
• Peso molecular: 663.43 (anhydrous basis)
• Beilstein: 3584133
• Reaxy-Rn: 5234782
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5234782&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Clase (5'->5')-dinucleotides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Clase: (5'->5')-dinucleotides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: (5'->5')-dinucleotides
• Alternative Parents: Purine nucleotide sugars Purine ribonucleoside diphosphates Purine ribonucleoside monophosphates Nicotinamide nucleotides Pentose phosphates Glycosylamines Monosaccharide phosphates 6-aminopurines Organic pyrophosphates Nicotinamides Monoalkyl phosphates Aminopyrimidines and derivatives Imidolactams Pyridinium derivatives N-substituted imidazoles Heteroaromatic compounds Tetrahydrofurans Secondary alcohols Oxacyclic compounds Azacyclic compounds Carboximidic acids Hydrocarbon derivatives Organic oxides Organic zwitterions Organopnictogen compounds Primary amines
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: (5'->5')-dinucleotide - Purine nucleotide sugar - Purine ribonucleoside diphosphate - Purine ribonucleoside monophosphate - Nicotinamide-nucleotide - Pyridine nucleotide - Pentose-5-phosphate - Pentose phosphate - Glycosyl compound - N-glycosyl compound - 6-aminopurine - Monosaccharide phosphate - Organic pyrophosphate - Purine - Imidazopyrimidine - Nicotinamide - Monoalkyl phosphate - Aminopyrimidine - Monosaccharide - N-substituted imidazole - Organic phosphoric acid derivative - Imidolactam - Phosphoric acid ester - Alkyl phosphate - Pyrimidine - Pyridinium - Pyridine - Tetrahydrofuran - Azole - Imidazole - Heteroaromatic compound - Secondary alcohol - Carboximidic acid derivative - Carboximidic acid - Organoheterocyclic compound - Oxacycle - Azacycle - Hydrocarbon derivative - Organopnictogen compound - Organic oxide - Organic zwitterion - Primary amine - Organonitrogen compound - Amine - Organic nitrogen compound - Alcohol - Organic oxygen compound - Organooxygen compound - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as (5'->5')-dinucleotides. These are dinucleotides where the two bases are connected via a (5'->5')-phosphodiester linkage.
• External Descriptors: NAD

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

TRPM2 Tchem Transient receptor potential cation channel subfamily M member 2 (0 Activities)

Discover Target: TRPM2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

P2RY11 Tchem P2Y purinoceptor 11 (0 Activities)

Discover Target: P2RY11

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Propiedades químicas y físicas

• Sensibilidad: heat sensitive；Moisture sensitive
• Peso molecular: 663.400 g/mol
• XLogP3: -6.000
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 18
• Rotatable Bond Count: 11
• Exact Mass: 663.109 Da
• Monoisotopic Mass: 663.109 Da
• Topological Polar Surface Area: 321.000 Ų
• Heavy Atom Count: 44
• Formal Charge: 0
• Complexity: 1120.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 8
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

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90. Xinyue Jiang, Yating Shang, Rahimi Hajar, Heng Yang, Jiaxin Peng, Jianhui Li, Weimin Wang, Zhaoyong Zou, Yuqun Xie.  (2025)  Evolutionary pattern of liquid-liquid phase separation in amphiphilic molecular self-assembly during the natural aging process of strong-aroma Baijiu.  FOOD RESEARCH INTERNATIONAL,      [PMID:41508481] [10.1016/j.foodres.2025.118060]

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93. Fan Xu, Yizheng Lv, Longhao Yang, Like Fan, Zhiyi Zhang, Dawei Ni, Wenli Zhang, Junmei Ding, Wanmeng Mu.  (2026)  Identification of a D-galactitol 2-dehydrogenase from a Rhizobiaceae bacterium for D-tagatose production.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41592382] [10.1016/j.ijbiomac.2026.150550]

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98. Nan Chen, Shuai Zhao, Zhiyong Yin, Samiullah Khan, Jianjun Guo, Min Zhao.  (2026)  The potential of Protaetia brevitarsis as a functional food that enhances immune function and gut microbiota in mice.  iScience,      [PMID:41858617] [10.1016/j.isci.2026.114939]

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