Nigericin sodium salt Ready Made Solution - 5mg/mL (DMSO:ethanol 1:1) , CAS No.28643-80-3

CAS: 28643-80-3 Cat. No.: N466621 Peso molecular: 746.94 Beilstein Registry Number: 3892398 Número EC: 608-231-4 PubChem CID: 16760591

GRADE & PURITY 5mg/mL (DMSO:ethanol 1:1)

Synonyms

NIGERICIN, MONOSODIUM SALT | Q27276393 | NIGERICIN SODIUM SALT [MI] | Nigericin, sodium salt (1:1) | Nigericin (sodium salt) | Nigericin sodium salt | MLS001336038 | D82021 | Sodium;(2R)-2-[(3S,6R)-6-[[(2S,4R,5R,6R,7R,9R)-2-[(5S)-5-[(2R,3S,5R)-5-[(2S,3S,5

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

Sinónimos

NIGERICIN, MONOSODIUM SALT | Q27276393 | NIGERICIN SODIUM SALT [MI] | Nigericin, sodium salt (1:1) | Nigericin (sodium salt) | Nigericin sodium salt | MLS001336038 | D82021 | Sodium;(2R)-2-[(3S, 6R)-6-[[(2S, 4R, 5R, 6R, 7R, 9R)-2-[(5S)-5-[(2R, 3S, 5R)-5-[(2S, 3S, 5

Especificaciones y pureza

5mg/mL (DMSO:ethanol 1:1)

Mecanismos bioquímicos y fisiológicos

Nigericin is a polyether ionophore which catalyzes the electroneutral exchange of alkali metal (K+) for H+(antiport). Nigericin transports monovalent cations across membranes with the following specificity: K+>Rb+>Cs+>>Na+and thus

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nombres e identificadores

• Sonrisas canónicas: CC1CCC(OC1C(C)C(=O)[O-])CC2CC(C(C3(O2)C(CC(O3)(C)C4CCC(O4)(C)C5C(CC(O5)C6C(CC(C(O6)(CO)O)C)C)C)C)C)OC.[Na+]
• IUPAC Name: sodium;(2R)-2-[(2R,3S,6R)-6-[[(2S,4R,5R,6R,7R,9R)-2-[(2R,5S)-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-7-methoxy-2,4,6-trimethyl-1,10-dioxaspiro[4.5]decan-9-yl]methyl]-3-methyloxan-2-yl]propanoate
• InChIKey: MOYOTUKECQMGHE-PDEFJWSRSA-M
• INCHI: 1S/C40H68O11.Na/c1-21-11-12-28(46-33(21)26(6)36(42)43)17-29-18-30(45-10)27(7)40(48-29)25(5)19-38(9,51-40)32-13-14-37(8,49-32)35-23(3)16-31(47-35)34-22(2)15-24(4)39(44,20-41)50-34;/h21-35,41,44H,11-20H2,1-10H3,(H,42,43);/q;+1/p-1/t21-,22-,23-,24+,25+,26+,27+,28+,29+,30+,31+,32+,33+,34-,35+,37-,38-,39-,40+;/m0./s1
• Isómeros SMILES: C[C@H]1CC[C@@H](O[C@H]1[C@@H](C)C(=O)[O-])C[C@@H]2C[C@H]([C@H]([C@@]3(O2)[C@@H](C[C@@](O3)(C)[C@H]4CC[C@@](O4)(C)[C@H]5[C@H](C[C@@H](O5)[C@@H]6[C@H](C[C@H]([C@@](O6)(CO)O)C)C)C)C)C)OC.[Na+]
• WGK Alemania: 3
• RTECS: QT6840000
• PubChem CID: 16760591
• Número ONU: 3462
• Peso molecular: 746.94
• Beilstein: 3892398

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Clase Organooxygen compounds
      • Subclass Ethers
        • Level5 Acetals
          • Level6 Ketals

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Clase: Organooxygen compounds
• Subclass: Ethers
• Intermediate Tree Nodes: Acetals
• Direct Parent: Ketals
• Alternative Parents: Oxanes Oxolanes Hemiacetals Carboxylic acid salts Oxacyclic compounds Monocarboxylic acids and derivatives Dialkyl ethers Carboxylic acids Primary alcohols Organic zwitterions Organic sodium salts Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteropolycyclic compounds
• Substituents: Ketal - Oxane - Oxolane - Carboxylic acid salt - Hemiacetal - Carboxylic acid derivative - Carboxylic acid - Dialkyl ether - Monocarboxylic acid or derivatives - Oxacycle - Organic alkali metal salt - Organoheterocyclic compound - Alcohol - Hydrocarbon derivative - Organic oxide - Primary alcohol - Organic zwitterion - Organic salt - Carbonyl group - Organic sodium salt - Aliphatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as ketals. These are acetals derived from ketones by replacement of the oxo group by two hydrocarbyloxy groups R2C(OR)2 ( R not Hydrogen ). This term, once abandoned, has been reinstated as a subclass of acetals.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

ACHE Tclin Acetylcholinesterase (18204 Activities)

Discover Target: ACHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Peso molecular: 746.900 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 9
• Exact Mass: 746.458 Da
• Monoisotopic Mass: 746.458 Da
• Topological Polar Surface Area: 145.000 Ų
• Heavy Atom Count: 52
• Formal Charge: 0
• Complexity: 1240.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 19
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Referencias

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