Recombinant Human FGF basic/FGF2/bFGF Protein, ≥95% (SDS-PAGE), CAS No.62031-54-3

CAS: 62031-54-3 Cat. No.: rp155946 Peso molecular: 17kD

GRADE & PURITY Animal Free, Carrier Free, Bioactive, ActiBioPure™, High Performance, ≥95%(SDS-PAGE)

Expression System

Oryza sativa

Accession #

P09038

Protein Tag

No tag

Expression system

Oryza sativa

Endotoxin Concentration

<1.0 EU/μg

Bioactivity

Measured in a cell proliferation assay using BALB/3T3 mouse embryo fibroblasts cell line. The ED₅₀ for this effect is typically <1 ng/mL.

Descripción general

Basic fibroblast growth factor (bFGF, FGF2 or FGF-β) is a member of the fibroblast growth factor family. bFGF is a kind of single-chain polypeptide growth factor, which plays an important role in promoting cell proliferation. It can also inhibit cell apoptosis, accelerate wound healing and induce blood vessel regeneration. In many cell types, such as mesoderm and neuroectoderm, bFGF is also very effective in inducing DNA synthesis. OsrhbFGF is expressed by rice endosperm cells and purified by gene recombination technology.

Specifications

Product Name

Recombinant Human FGF basic/FGF2/bFGF Protein, ≥95% (SDS-PAGE), CAS No.62031-54-3

Sinónimos

basic fibroblast growth factor bFGF | Basic fibroblast growth factor | bFGF | FGF basic | FGF2 | FGF-2 | FGFBprostatropin | fibroblast growth factor 2 (basic) | HBGF-2 | heparin-binding growth factor 2 | Prostatropin

Grado

ActiBioPure™, Animal Free, Bioactive, Carrier Free, High Performance

Especificaciones y pureza

Animal Free, Carrier Free, Bioactive, ActiBioPure™, High Performance, ≥95%(SDS-PAGE)

Mecanismos bioquímicos y fisiológicos

Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and ce

Pureza

≥95% (SDS-PAGE)

Bioactividad

Measured in a cell proliferation assay using BALB/3T3 mouse embryo fibroblasts cell line. The ED₅₀ for this effect is typically <1 ng/mL.

Concentración de endotoxinas

<1.0 EU/μg

Sistema de expresión

Oryza sativa

Especie

Human

Aminoácidos

134-288 aa

Secuencia

MAAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS

Etiqueta proteínica

No tag

Longitud de la proteína

Full length protein

Número de adhesión

P09038

Fuente

Recombinant

Peso molecular previsto

17 kDa

CAS

62031-54-3

Tipo de molécula

Protein

Almacenamiento y envío

Forma

Lyophilized

Reconstitución

It is recommended to redissolve the lyophilized powder in sterile water to 100-200 μg/ml, and further dilute it in other solvents.

Condiciones de almacenamiento de almacenamiento

Store at -20°C,Avoid repeated freezing and thawing

Enviado en

Ice chest + Ice pads

Estabilidad y almacenamiento

Store at -20 ℃ for 36 months. Upon delivery aliquot. Avoid freeze/thaw cycle. Upon reconstitution, the product should be stored at 2-8 ℃ for 2-7 days and used up as soon as possible. For future use, should be stored at -20 ℃.

Imágenes

Protein Bioactivity: Recombinant Human FGF basic/FGF2/bFGF(155aa) Protein (rp155946)

Recombinant Human FGF basic/FGF2/bFGF(155aa) Protein (rp155946) - Protein Bioactivity
Measured in a cell proliferation assay using BALB/3T3 mouse embryo fibroblasts cell line. The ED₅₀ for this effect is typically less than 1.0 ng/mL.

SDS-PAGE: Recombinant Human FGF basic/FGF2/bFGF(155aa) Protein (rp155946)

Recombinant Human FGF basic/FGF2/bFGF(155aa) Protein (rp155946)-SDS-PAGE
3μg/lane of Recombinant Human FGF2 was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 16.0 kDa.

Referencias

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2. Yang Min, Ma Yuejiang, Cao Zhu, Zhan Hong, Jin Ye, Huang Xiufeng, Yang Shizhou.  (2025)  HPV16 E7 Enhances Cell Stemness via RTKN2-Mediated Activation of the NF-κB Pathway in Cervical Cancer.  BIOCHEMICAL GENETICS,      [PMID:40495058] [10.1007/s10528-025-11144-w]

3. Xiaoshen Zhang, Tao Jiang, Lingyun Ye, Jianguo Sun, Lei Wang, Juanjuan Li, Fengying Wu, Shengxiang Ren, Guanghui Gao.  (2025)  WISP3 upregulates SDCBP expression to promote the progression of non-small cell lung cancer via the TGF-β signaling pathway.  BIOCHEMICAL PHARMACOLOGY,      [PMID:40571215] [10.1016/j.bcp.2025.117082]

4. Jianan Li, Jingqi Huang, Zeyang Gao, Chunpeng He, Zaiyan Xu, Bo Zuo.  (2025)  A novel proliferation synergy factor cocktail maintains proliferation and improves transfection efficiency in muscle cells and fibroblasts under low-serum conditions.  Frontiers in Cell and Developmental Biology,      [PMID:41332986] [10.3389/fcell.2025.1680263]

5. Yang Shizhou, Wu Tingting, Cao Zhu, Chen Zhengyun, Ma Yuejiang, Wang Ting, Qian Linhua, Huang Xiufeng.  (2026)  Hypoxic glycolysis-driven histone lactylation activates NHE7 to promote endometrial cancer progression via COX6C-mediated endoplasmic reticulum stress.  APOPTOSIS,  31  (2): (55).  [PMID:41575611] [10.1007/s10495-026-02262-w]

6. Liping Zhang, Yanyan Wang, Wenxin Qiu, Shuangling Liu, Shengxuan Xu, Hongwei Wang, Lin Yuan.  (2026)  Dual-loaded exosomes with fibroblast growth factor 2 and retinoic acid enhance directed neural differentiation of embryonic stem cells.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:41691875] [10.1016/j.colsurfb.2026.115554]