WST-8 - 10mM in Water , CAS No.193149-74-5

CAS: 193149-74-5 Cat. No.: W422359 Peso molecular: 600.47 Número EC: 693-016-8 PubChem CID: 9894947

GRADE & PURITY 10mM in Water

Synonyms

193149-74-5|WST-8|2-(2-Methoxy-4-nitrophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium Sodium Salt|270078-53-0|MFCD09264687|sodium 4-(3-(2-methoxy-4-nitrophenyl)-2-(4-nitrophenyl)-2H-tetrazol-3-ium-5-yl)benzene-1,3-disulfonate|sodium;4-[2-(2

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

WST-8 is a next generation tetrazolium reagent that serves as a sensitive chromogenic indicator for NADH. It is reduced by NADH at neutral pHs in the presence of 1-methoxy PMS to produce the corresponding formazan dye that absorbs at 460 nM. Useful as a cell viability indicator in cell proliferation assays.
A tetrazolium reagent that serves as a chromogenic indicator for NADH.

Specifications

Sinónimos

193149-74-5 | WST-8 | 2-(2-Methoxy-4-nitrophenyl)-3-(4-nitrophenyl)-5-(2, 4-disulfophenyl)-2H-tetrazolium Sodium Salt | 270078-53-0 | MFCD09264687 | sodium 4-(3-(2-methoxy-4-nitrophenyl)-2-(4-nitrophenyl)-2H-tetrazol-3-ium-5-yl)benzene-1, 3-disulfonate | sodium;4-[2-(2

Especificaciones y pureza

10mM in Water

Condiciones de almacenamiento de almacenamiento

Protected from light, Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nombres e identificadores

• Sonrisas canónicas: COC1=C(C=CC(=C1)[N+](=O)[O-])[N+]2=NC(=NN2C3=CC=C(C=C3)[N+](=O)[O-])C4=C(C=C(C=C4)S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+]
• IUPAC Name: sodium;4-[2-(2-methoxy-4-nitrophenyl)-3-(4-nitrophenyl)tetrazol-2-ium-5-yl]benzene-1,3-disulfonate
• InChIKey: VSIVTUIKYVGDCX-UHFFFAOYSA-M
• INCHI: 1S/C20H14N6O11S2.Na/c1-37-18-10-14(26(29)30)6-9-17(18)24-22-20(21-23(24)12-2-4-13(5-3-12)25(27)28)16-8-7-15(38(31,32)33)11-19(16)39(34,35)36;/h2-11H,1H3,(H-,31,32,33,34,35,36);/q;+1/p-1
• Isómeros SMILES: COC1=C(C=CC(=C1)[N+](=O)[O-])[N+]2=NC(=NN2C3=CC=C(C=C3)[N+](=O)[O-])C4=C(C=C(C=C4)S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+]
• PubChem CID: 9894947
• Peso molecular: 600.47

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Azoles
      • Subclass Tetrazoles

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Azoles
• Subclass: Tetrazoles
• Intermediate Tree Nodes: Not available
• Direct Parent: Phenyltetrazoles and derivatives
• Alternative Parents: Nitrophenyl ethers Benzenesulfonic acids and derivatives 1-sulfo,2-unsubstituted aromatic compounds Benzenesulfonyl compounds Methoxyanilines Anisoles Phenoxy compounds Methoxybenzenes Nitroaromatic compounds Alkyl aryl ethers Sulfonyls Organosulfonic acids Heteroaromatic compounds Azacyclic compounds Propargyl-type 1,3-dipolar organic compounds Organic oxoazanium compounds Organonitrogen compounds Hydrocarbon derivatives Organic oxides Organic sodium salts Organic cations
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Nitrophenyl ether - Phenyltetrazole - Benzenesulfonate - Arylsulfonic acid or derivatives - Benzenesulfonyl group - 1-sulfo,2-unsubstituted aromatic compound - Nitrobenzene - Methoxyaniline - Phenoxy compound - Nitroaromatic compound - Anisole - Phenol ether - Methoxybenzene - Alkyl aryl ether - Monocyclic benzene moiety - Benzenoid - Sulfonyl - Organosulfonic acid - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Heteroaromatic compound - Organic nitro compound - C-nitro compound - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Allyl-type 1,3-dipolar organic compound - Organic oxoazanium - Organic alkali metal salt - Azacycle - Ether - Organic nitrogen compound - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Organosulfur compound - Organic salt - Organic sodium salt - Hydrocarbon derivative - Organic oxide - Organic cation - Aromatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as phenyltetrazoles and derivatives. These are compounds containing a phenyltetrazole skeleton, which consists of a tetrazole bound to a phenyl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Sensibilidad: Light sensitive
• Peso molecular: 600.500 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 13
• Rotatable Bond Count: 4
• Exact Mass: 599.998 Da
• Monoisotopic Mass: 599.998 Da
• Topological Polar Surface Area: 267.000 Ų
• Heavy Atom Count: 40
• Formal Charge: 0
• Complexity: 1080.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Referencias

1. Jiaxuan Wang, Cuiping Pang, Zhonglin Tu, Jianghua Li, Guocheng Du, Guoqiang Zhang.  (2024)  Double enzymes coupled screening assisted molecular modification of α-Amino acid ester acyltransferase for L-Alanyl-l-Glutamine biosynthesis.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2024.103643]

2. Peifang Wang, Yue Su, Min Ma, Yuqing Wang, Shuang Hou, Changqing Wang, Lin Sun, Jianshe Wei, Mingxue Li.  (2024)  Thiosemicarbazones-Loaded Injectable Hydrogels with Self-Healing and Antibacterial Activity for Wound Healing.  ACS Applied Polymer Materials,      [PMID:] [10.1021/acsapm.4c00994]

3. Deng Ruotong, Chen Wei, Zhu Hanjie, Li Yuxi, Ou Yining, Wang Jian, Ruan Qing, Zhang Xuanying, Zhang Junbo, Zhang Yongxian, Niu Yantao, Hu Zhubin, Zhang Chunlei, Xu Huaping, Cao Wei.  (2025)  Molecular engineering of melanin for enhanced biological γ-ray protection.  Nature Communications,  16  (1): (1-17).  [PMID:40849435] [10.1038/s41467-025-62403-8]

4. Weiman Zhang, Mei Wang, Weibiao Wang, Fen Ma, Shuxian Zhang, Zhigang Yang, Yue Zhang, Yuping Sa, Tao Gao, Xinmin He, Guoning Chen, Xueqin Ma.  (2025)  Unveiling Hidden Threats: Novel Detection of Acetaldehyde Dehydrogenase Inhibitors in Everyday Foods.  LWT-FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.lwt.2025.117768]