Ascorbic acid - PrimorTrace™, ≥99.99% metals basis , Sodium-dependent vitamin C transporter 1;Sodium-dependent vitamin C transporter 2, CAS No.50-81-7, Sodium-dependent vitamin C transporter 1;Sodium-dependent vitamin C transporter 2

CAS: 50-81-7 Cat. No.: A103534 分子式: C₆H₈O₆ 分子量: 176.12 Beilstein Registry Number: 84272 EC番号: 200-066-2

グレード＆純度 PrimorTrace™, ≥99.99% metals basis

Synonyms

Ascorbicap | C-Long | Ferrous ascorbate | phosphorus oxichloride | Ceglion | Cenetone | Cetemican | hexamethyl-disiloxane | Ascorb | Cemagyl | Cipca | Planavit C | Secorbate | Vitacee | Ascorbicab | Scorbacid | Cecon | C-Span | Duoscorb | pentakis(chloran

Storage

Protected from light,Room temperature,Argon charged,Desiccated

Shipped In

Normal

概要

A calcium channel inhibitor.

仕様

同義語

Ascorbicap | C-Long | Ferrous ascorbate | phosphorus oxichloride | Ceglion | Cenetone | Cetemican | hexamethyl-disiloxane | Ascorb | Cemagyl | Cipca | Planavit C | Secorbate | Vitacee | Ascorbicab | Scorbacid | Cecon | C-Span | Duoscorb | pentakis(chloran

仕様と純度

PrimorTrace™, ≥99.99% metals basis

生化学的・生理学的メカニズム

It protects cells against the damaging effects of radiation and oxygen radicals,increases the rate of mineralization in osteoblasts,reduces Na+/Ca2+ exchange in cultured astrocytes,modulates cyclic nucleotide levels in B and T cells inhibits apoptosis in

保管条件

Protected from light,Room temperature,Argon charged,Desiccated

入荷

Normal

等級

PrimorTrace™

作用メカニズム

Sodium-dependent vitamin C transporter 1;Sodium-dependent vitamin C transporter 2

純度

≥99.99% metals basis

名前と識別子

パブケム・シド

508813559

パブケム・シド・ウル

https://pubchem.ncbi.nlm.nih.gov/substance/508813559

カノニカル・スマイル

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

IUPAC Name

(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one

InChIKey

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

INCHI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

異性体SMILES

C([C@@H]([C@@H]1C(=C(C(=O)O1)O)O)O)O

WGKドイツ

1

RTECS

CI7650000

代替CAS番号

53262-66-1,6730-29-6,50-81-7,134-03-2 (monosodium salt)

NSC番号

UN 1648

UN番号

3

MeSH用語

Acid, Ascorbic;Acid, L-Ascorbic;Ascorbate, Ferrous;Ascorbate, Magnesium;Ascorbate, Sodium;Ascorbic Acid;Ascorbic Acid, Monosodium Salt;di-L-Ascorbate, Magnesium;Ferrous Ascorbate;Hybrin;L Ascorbic Acid;L-Ascorbic Acid;Magnesium Ascorbate;Magnesium Ascorbi

分子量

176.12

Beilstein

84272

Reaxy-Rn

84272

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=84272&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • 分類 Dihydrofurans
      • Subclass Furanones

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• 分類: Dihydrofurans
• Subclass: Furanones
• Intermediate Tree Nodes: Not available
• Direct Parent: Butenolides
• Alternative Parents: Vinylogous acids Enoate esters Secondary alcohols Lactones Enediols 1,2-diols Oxacyclic compounds Monocarboxylic acids and derivatives Primary alcohols Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: 2-furanone - Vinylogous acid - Alpha,beta-unsaturated carboxylic ester - Enoate ester - 1,2-diol - Carboxylic acid ester - Enediol - Secondary alcohol - Lactone - Carboxylic acid derivative - Oxacycle - Monocarboxylic acid or derivatives - Alcohol - Hydrocarbon derivative - Organic oxygen compound - Carbonyl group - Organic oxide - Primary alcohol - Organooxygen compound - Aliphatic heteromonocyclic compound
• 説明: This compound belongs to the class of organic compounds known as butenolides. These are dihydrofurans with a carbonyl group at the C2 carbon atom.
• External Descriptors: Water-soluble vitamins

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

関連ターゲット（人間）

SLC23A1 Tchem Solute carrier family 23 member 1 (0 Activities)

Discover Target: SLC23A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC23A2 Tbio Solute carrier family 23 member 2 (0 Activities)

Discover Target: SLC23A2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ADRA2B Tclin Alpha-2B adrenergic receptor (0 Activities)

Discover Target: ADRA2B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

VDR Tclin Vitamin D receptor (26531 Activities)

Discover Target: VDR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Lymphoblastoid cell (5959 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

Discover Target: EHMT2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

L3MBTL1 Tchem Lethal(3)malignant brain tumor-like protein 1 (14536 Activities)

Discover Target: L3MBTL1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LMNA Tbio Prelamin-A/C (36751 Activities)

Discover Target: LMNA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GMNN Tbio Geminin (128009 Activities)

Discover Target: GMNN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)

Discover Target: CBX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

関連ターゲット（非人間）

Plasmodium falciparum (966862 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

lef Anthrax lethal factor (7585 Activities)

Discover Target: lef

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TGR Thioredoxin glutathione reductase (28579 Activities)

Discover Target: TGR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

作用メカニズム

化学的性質と物理的性質

• 感度: Light sensitive.Air sensitive
• 比旋光度［α］: 21 ° (C=10, H2O)
• 融点（°C）: 190-192°C
• 分子量: 176.120 g/mol
• XLogP3: -1.600
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 176.032 Da
• Monoisotopic Mass: 176.032 Da
• Topological Polar Surface Area: 107.000 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 232.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1