≥98%(GC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Product Application：
4-Chloro-2-methoxyphenol, is used as an intermediate in pharmaceutical research, pharmaceutical chemicals and reagents. It is also used as an application intermediate. it can be used to produce 4-Chloro-2-methoxy-6-nitrophenol.
| Pubchem Sid | 504753376 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504753376 |
| Canonical Smiles | COC1=C(C=CC(=C1)Cl)O |
| IUPAC Name | 4-chloro-2-methoxyphenol |
| InChIKey | FVZQMMMRFNURSH-UHFFFAOYSA-N |
| INCHI | 1S/C7H7ClO2/c1-10-7-4-5(8)2-3-6(7)9/h2-4,9H,1H3 |
| Isomeric SMILES | COC1=C(C=CC(=C1)Cl)O |
| Molecular Weight | 158.58 |
| Beilstein | 6(4)5614 |
| Reaxy-Rn | 1940516 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1940516&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Phenols |
| Subclass | Methoxyphenols |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Methoxyphenols |
| Alternative Parents | Phenoxy compounds P-chlorophenols Methoxybenzenes Anisoles Chlorobenzenes Alkyl aryl ethers 1-hydroxy-2-unsubstituted benzenoids Aryl chlorides Organochlorides Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Methoxyphenol - Anisole - 4-halophenol - Phenoxy compound - 4-chlorophenol - Phenol ether - Methoxybenzene - Alkyl aryl ether - Halobenzene - Chlorobenzene - 1-hydroxy-2-unsubstituted benzenoid - Aryl chloride - Aryl halide - Monocyclic benzene moiety - Ether - Organooxygen compound - Organochloride - Organohalogen compound - Hydrocarbon derivative - Organic oxygen compound - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as methoxyphenols. These are compounds containing a methoxy group attached to the benzene ring of a phenol moiety. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 L1707091 | Certificate of Analysis | Jul 15, 2025 | C153525 |
| F2420174 | Certificate of Analysis | May 18, 2024 | C153525 |
| F2420175 | Certificate of Analysis | May 18, 2024 | C153525 |
| F2420176 | Certificate of Analysis | May 18, 2024 | C153525 |
| F2420177 | Certificate of Analysis | May 18, 2024 | C153525 |
| F2420178 | Certificate of Analysis | May 18, 2024 | C153525 |
| B2309133 | Certificate of Analysis | Dec 17, 2022 | C153525 |
| B2309134 | Certificate of Analysis | Dec 17, 2022 | C153525 |
| B2309338 | Certificate of Analysis | Dec 17, 2022 | C153525 |
| B2309346 | Certificate of Analysis | Dec 17, 2022 | C153525 |
| Solubility | It is slightly soluble in water. |
|---|---|
| Refractive Index | 1.56 |
| Boil Point(°C) | 241 °C |
| Melt Point(°C) | 16-17° |
| Molecular Weight | 158.580 g/mol |
| XLogP3 | 1.500 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 1 |
| Exact Mass | 158.013 Da |
| Monoisotopic Mass | 158.013 Da |
| Topological Polar Surface Area | 29.500 Ų |
| Heavy Atom Count | 10 |
| Formal Charge | 0 |
| Complexity | 108.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Ping Hu, Shengwen Lei, Weiyan Luo, Xiaoqing Huang, Wei Ruan, Yueyuan Ye, Zhifeng Zheng, Dechao Wang, Duo Wang. (2023) Recovery of high-purity-4-chloroguaiacol from bleaching wastewater by a heterogeneous extraction method. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, [PMID:] [10.1002/jctb.7518] |
