1,2-dipalmitoyl-sn-glycero-3-phospho-L-serine (sodium salt) - ≥98% , CAS No.145849-32-7

CAS: 145849-32-7 Cat. No.: D130323 Molecular Weight: 757.95 PubChem CID: 46891791

GRADE & PURITY ≥98%

Synonyms

16:0 PS | AS-71551 | sodium (2S)-2-azaniumyl-3-{[(2R)-2,3-bis(hexadecanoyloxy)propyl phosphonato]oxy}propanoate | 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE (MONOSODIUM SALT) | PD019009 | 12-Dipalmitoyl-sn-glycero-3-PS sodium salt | AKOS037646928 | DTX

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Application

228,229

Overview

Product Introduction

Phosphatidylserine (PtdSer) is an anionic phospholipid abundantly present in the eukaryotic cell. 10% of the total cellular lipid consists of phosphatidylserine. O‐phospho‐L‐serine is a heat‐stable substrate.

Application

16:0 PS has been used in the assay to measure interactions between purified dynamin-related protein 1 (Drp1) and synthetic liposomes.

16:0 PS may be used in liposome flotation assay to measure its interactions between purified dynamin related protein 1 (Drp1) and as a component in the lipid mixtures to prepare lipid monolayers. It has also been used to prepare liposomes by the lipid film hydration method.

Specifications

Synonyms

16:0 PS | AS-71551 | sodium (2S)-2-azaniumyl-3-{[(2R)-2, 3-bis(hexadecanoyloxy)propyl phosphonato]oxy}propanoate | 1, 2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE (MONOSODIUM SALT) | PD019009 | 12-Dipalmitoyl-sn-glycero-3-PS sodium salt | AKOS037646928 | DTX

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

Phosphatidylserine (PtdSer) participates in various intracellular signaling pathways. It also play a major role in apoptosis and blood clotting.

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 504770836
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504770836
• Canonical Smiles: CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC(C(=O)[O-])[NH3+])OC(=O)CCCCCCCCCCCCCCC.[Na+]
• IUPAC Name: sodium;(2S)-2-azaniumyl-3-[[(2R)-2,3-di(hexadecanoyloxy)propoxy]-oxidophosphoryl]oxypropanoate
• InChIKey: GTLXLANTBWYXGW-CEGNZRHUSA-M
• INCHI: 1S/C38H74NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-36(40)46-31-34(32-47-50(44,45)48-33-35(39)38(42)43)49-37(41)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h34-35H,3-33,39H2,1-2H3,(H,42,43)(H,44,45);/q;+1/p-1/t34-,35+;/m1./s1
• Isomeric SMILES: CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OC[C@@H](C(=O)[O-])[NH3+])OC(=O)CCCCCCCCCCCCCCC.[Na+]
• PubChem CID: 46891791
• Molecular Weight: 757.95

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Class Glycerophospholipids
      • Subclass Glycerophosphoserines

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Class: Glycerophospholipids
• Subclass: Glycerophosphoserines
• Intermediate Tree Nodes: Not available
• Direct Parent: Phosphatidylserines
• Alternative Parents: L-alpha-amino acids Tricarboxylic acids and derivatives Fatty acid esters Dialkyl phosphates Quaternary ammonium salts Carboxylic acid salts Carboxylic acid esters Carboxylic acids Organic zwitterions Organic sodium salts Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Diacyl-glycerol-3-phosphoserine - Alpha-amino acid - Alpha-amino acid or derivatives - L-alpha-amino acid - Tricarboxylic acid or derivatives - Fatty acid ester - Dialkyl phosphate - Organic phosphoric acid derivative - Phosphoric acid ester - Alkyl phosphate - Fatty acyl - Quaternary ammonium salt - Carboxylic acid ester - Carboxylic acid salt - Carboxylic acid derivative - Organic alkali metal salt - Carboxylic acid - Amine - Organonitrogen compound - Primary aliphatic amine - Organic oxide - Organooxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxygen compound - Carbonyl group - Organic sodium salt - Organic zwitterion - Organic salt - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as phosphatidylserines. These are glycerophosphoserines in which two fatty acids are bonded to the glycerol moiety through ester linkages.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Molecular Weight: 757.900 g/mol
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 39
• Exact Mass: 757.487 Da
• Monoisotopic Mass: 757.487 Da
• Topological Polar Surface Area: 179.000 Ų
• Heavy Atom Count: 51
• Formal Charge: 0
• Complexity: 861.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

References

1. Yang Ruilin, Wang Ping, Guan Xinhui, Gu Xiaofei, Qiao Xiaoqiang.  (2025)  Exploiting metal-free atom transfer radical polymerization for fabrication of styrene-maleic acid polymer-brush grafting chromatographic stationary phase and its separation performances for phospholipids.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,      [PMID:40781368] [10.1007/s00216-025-06053-1]