Modifying enzymes

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  1. 5' DNA/RNA Adenylase
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. DNase, RNase free ? Free of DNase and RNase activity to keep DNA and RNA intact. Use in nucleic-acid extraction, PCR, and storage where degradation is a risk. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. EnzymoPure™ ? EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance. Sterile ? Sterile grade — processed and verified free of viable microorganisms. Use directly in aseptic procedures and cell culture without further sterilization. 75 U/µL
    ◐ .US Made to order · 2–4 wks Item #: D743509
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    Technical Identifiers
    Species
    Adenosylase gene of thermophilic bacteria
    Accession #
    8UCH_A,A0A075LQ94
    Expression system
    E. coli
    Bioactivity
    One unit is the amount of enzyme required to catalyze the transfer of 1pmol of AMP to pDNA substrate in a total reaction volume of 20μl in 15 minutes at 65℃.
    Synonyms
    Single-Strand Nucleic Acid 5' Adenylase
  2. AlkB (RNA/DNA demethylase, Nuclease-free)
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. RNase free ? RNase-free — verified without RNase activity to protect fragile RNA. Use in RNA extraction, RT-PCR, and any RNA-sensitive workflow. EnzymoPure™ ? EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance. Sterile ? Sterile grade — processed and verified free of viable microorganisms. Use directly in aseptic procedures and cell culture without further sterilization. 20 U/µL
    ● In Stock — US Item #: A743741
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    Species
    Escherichia coli (strain K12)
    Accession #
    P05050.1
    Expression system
    E. coli
    Bioactivity
    One unit (U) is the amount of AlkB that removes 90-100% of the m6A modifications in total RNA of HEK 293T cells in 20 ul of reaction mixture at 37℃ after 100minutes of incubation. Under the regular conditions, the enzymatic activity of 1 μg of AlkB is approximately 1 unit.
    Synonyms
    alkB | aidD | ECK2204
  3. Antarctic Phosphatase (Thermosensitive)
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. EnzymoPure™ ? EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance. Sterile ? Sterile grade — processed and verified free of viable microorganisms. Use directly in aseptic procedures and cell culture without further sterilization. ≥90%(SDS-PAGE) 5.0 U/µl
    ◐ .US Made to order · 2–4 wks Item #: A743821
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    Species
    Antarctic bacterium TAB5
    Accession #
    2W5W_B,Q9KWY4
    Expression system
    E. coli
    Bioactivity
    1 unit refers to the 5 'concave end produced by restriction endonuclease digestion at 37 ℃ for 30 minutes. The enzyme amount required for dephosphorylation of µ g pUC19 vector DNA. The dephosphorylation standard refers to the self linking reaction Can inhibit>95% of DNA re circularization and detect it by transforming E. coli cells.
    Synonyms
    Thermosensitive phosphatase
  4. E.coli DNA Polymerase I
    EnzymoPure™ ? EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance. free of other DNA exonucleases or endonucleases, free of RNase.
    ◐ .US Made to order · 2–4 wks Item #: E745501
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  5. Klenow Fragment, Exo-
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. EnzymoPure™ ? EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance. Sterile ? Sterile grade — processed and verified free of viable microorganisms. Use directly in aseptic procedures and cell culture without further sterilization. 5 U/μL
    ◐ .US Made to order · 2–4 wks Item #: K747451
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    Technical Identifiers
    Species
    E. coli
    Accession #
    2KFZ_A,P00582
    Expression system
    E. coli
    Bioactivity
    One unit is the amount of enzyme required to catalyze the incorporation of 10nmol of deoxyribonucleotides (dNTPs) into a polynucleotide within 30 minutes at 37℃.
    Synonyms
    DNA polymerase I Fragment Mutant
  6. Lambda Exonuclease
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. RNase free ? RNase-free — verified without RNase activity to protect fragile RNA. Use in RNA extraction, RT-PCR, and any RNA-sensitive workflow. EnzymoPure™ ? EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance. Sterile ? Sterile grade — processed and verified free of viable microorganisms. Use directly in aseptic procedures and cell culture without further sterilization. ≥95%(SDS-PAGE) 5.0 U/μL
    ◐ .US Made to order · 2–4 wks Item #: L747582
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    Technical Identifiers
    Synonyms
    λ Exonuclease | exo | lambdap24
  7. SP6 RNA Polymerase
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. RNase free ? RNase-free — verified without RNase activity to protect fragile RNA. Use in RNA extraction, RT-PCR, and any RNA-sensitive workflow. EnzymoPure™ ? EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance. Sterile ? Sterile grade — processed and verified free of viable microorganisms. Use directly in aseptic procedures and cell culture without further sterilization. 20 U/µL
    ◐ .US Made to order · 2–4 wks Item #: S750679
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    Technical Identifiers
    Species
    Enterobacteria phage SP6
    Accession #
    Q7Y5N4
    Expression system
    E. coli
    Bioactivity
    One unit of enzyme incorporates 1nmol of AMP into polynucleotide in 1 hour at 37°C under the following activity assay conditions.
  8. T7 Endonuclease I
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. RNase free ? RNase-free — verified without RNase activity to protect fragile RNA. Use in RNA extraction, RT-PCR, and any RNA-sensitive workflow. EnzymoPure™ ? EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance. Sterile ? Sterile grade — processed and verified free of viable microorganisms. Use directly in aseptic procedures and cell culture without further sterilization. 10 U/µL
    ◐ .US Made to order · 2–4 wks Item #: T750878
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    Technical Identifiers
    Species
    Escherichia phage T7
    Accession #
    P00641.1
    Expression system
    E. coli
    Bioactivity
    One unit is defined as the amount of enzyme required to convert > 90% of 1μg of supercoiled cruciform pUC(AT) to > 90% linear form in a total reaction volume of 50 μl in 1 hour at 37℃.
    Synonyms
    T7 Endo I | T7EI | T7p19
  9. Terminal Deoxynucleotidyl Transferase (TdT)
    Liquid Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. DNase, RNase free ? Free of DNase and RNase activity to keep DNA and RNA intact. Use in nucleic-acid extraction, PCR, and storage where degradation is a risk. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. EnzymoPure™ ? EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance. Sterile ? Sterile grade — processed and verified free of viable microorganisms. Use directly in aseptic procedures and cell culture without further sterilization. 5.0 U/μL
    ◐ .US Made to order · 2–4 wks Item #: T751007
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    Technical Identifiers
    Species
    Bovine
    Accession #
    P06526
    Expression system
    Pichia pastoris
    Bioactivity
    One Unit is the amount of enzyme required to catalyze the incorporation of 1 nmol of dNTP to the 3'-OH termini of a polynucleotide within 60 minutes at 37℃.
    Synonyms
    TdT | DNTT | ‌ DNA nucleotidylexotransferase‌‌ | Terminal addition enzyme‌‌ | Terminal deoxynucleotidyltransferase‌‌ ...
  10. Terminal Deoxynucleotidyl Transferase (TdT)
    CAS: 9027-67-2 EC Number: 232-819-6
    Liquid Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. DNase, RNase free ? Free of DNase and RNase activity to keep DNA and RNA intact. Use in nucleic-acid extraction, PCR, and storage where degradation is a risk. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. EnzymoPure™ ? EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance. Sterile ? Sterile grade — processed and verified free of viable microorganisms. Use directly in aseptic procedures and cell culture without further sterilization. 20 U/μL
    ◐ .US Made to order · 2–4 wks Item #: T751008
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    Pricing & Pack Sizes
    Technical Identifiers
    Species
    Bovine
    Accession #
    P06526
    Expression system
    E. coli
    Bioactivity
    One unit is the amount of enzyme required to catalyze the incorporation of 1 nmol of dNTP to the 3'-OH termini of a polynucleotide within 60 minutes at 37℃.
    Synonyms
    TdT | DNTT | ‌ DNA nucleotidylexotransferase‌‌ | Terminal addition enzyme‌‌ | Terminal deoxynucleotidyltransferase‌‌ ...
  11. Thermostable RNase H
    Liquid Suitable for molecular biology ? Molecular-biology grade — free of nucleases and contaminants that degrade DNA/RNA. Use in cloning, PCR, and nucleic-acid work needing clean reagents. BioReagent ? BioReagent grade — tested suitable for life-science and molecular-biology use. Use for cell culture, assays, and biochemical work needing biological compatibility. DNase, RNase free ? Free of DNase and RNase activity to keep DNA and RNA intact. Use in nucleic-acid extraction, PCR, and storage where degradation is a risk. EnzymoPure™ ? EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance. Sterile ? Sterile grade — processed and verified free of viable microorganisms. Use directly in aseptic procedures and cell culture without further sterilization. for DNA and RNA applications ? For nucleic-acid (DNA & RNA) applications — nuclease-controlled across both. Use in workflows handling DNA and RNA together where degradation is a risk. ≥95% 5 U/μl
    ◐ .US Made to order · 2–4 wks Item #: T751065
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    Technical Identifiers
    Synonyms
    Thermostable RNase H | RNase H
  12. Recombinant Cas9 Nuclease (SpCas9)
    CAS: 1425049-49-5
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. RNase free ? RNase-free — verified without RNase activity to protect fragile RNA. Use in RNA extraction, RT-PCR, and any RNA-sensitive workflow. EnzymoPure™ ? EnzymoPure™ — Aladdin's line of high-quality enzymatic solutions. Use when enzyme purity and defined activity drive assay or process performance. Sterile ? Sterile grade — processed and verified free of viable microorganisms. Use directly in aseptic procedures and cell culture without further sterilization. 1μM (158ng/μL )
    ◐ .US Made to order · 2–4 wks Item #: C744422
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    Technical Identifiers
    Species
    Streptococcus pyogenes serotype M1
    Accession #
    Q99ZW2.1
    Expression system
    E. coli
    Synonyms
    CRISPR-associated endonuclease Cas9 | Csn1
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Frequently Asked Questions

How do I choose the right Modifying enzymes product for my experiment?
Match the Modifying enzymes product to the application first — Western blot, ELISA, cell-based assay, and structural work make different demands. Then check species reactivity or source organism, format (lyophilised or solution), and whether you need an activity-verified lot.
What does Modifying enzymes cover?
Modifying enzymes is a top-level listing in our catalogue. Use the filters and search on the listing page to narrow by the attributes that matter for your work, or browse the neighbouring categories from the main navigation.
What specifications matter most for Modifying enzymes?
For Modifying enzymes, check purity by SDS-PAGE or HPLC, endotoxin level for cell-based work, specific activity, tag and expression system, and the reconstitution and storage conditions. Repeated freeze-thaw is the commonest cause of lost activity. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Modifying enzymes by target, species, or application?
Yes — filter Modifying enzymes by application, species reactivity or source, and format, and search by gene or protein name. For items not listed, contact [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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