1,2-Naphthoquinone-4-sulfonic acid sodium salt - ≥98% , CAS No.521-24-4

CAS: 521-24-4 Cat. No.: N111090 Molecular Weight: 260.2 Beilstein Registry Number: 4169788 EC Number: 208-308-9

GRADE & PURITY ≥98%

Synonyms

1,2-Naphthoquinone-4-sulfonic acid sodium salt | AKOS003614484 | Z57947969 | N0043 | .BETA.-NAPHTHOQUINONE-4-SULFONIC ACID SODIUM SALT | 1,2-NAPHTHOQUINONE-4-SULFONIC ACID SODIUM | AI3-50008 | EINECS 208-308-9 | SB19104 | 1,2-naphthoquinone-4-sulfonic aci

Storage

Store at 2-8°C

Shipped In

Wet ice

Overview

Usually used in the colorimetric assay for determination of procaine hydrochloride in pharmaceutical preparations.

Specifications

Synonyms

1, 2-Naphthoquinone-4-sulfonic acid sodium salt | AKOS003614484 | Z57947969 | N0043 | .BETA.-NAPHTHOQUINONE-4-SULFONIC ACID SODIUM SALT | 1, 2-NAPHTHOQUINONE-4-SULFONIC ACID SODIUM | AI3-50008 | EINECS 208-308-9 | SB19104 | 1, 2-naphthoquinone-4-sulfonic aci

Specifications & Purity

≥98%

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 504758986
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504758986
• Canonical Smiles: C1=CC=C2C(=C1)C(=CC(=O)C2=O)S(=O)(=O)[O-].[Na+]
• IUPAC Name: sodium;3,4-dioxonaphthalene-1-sulfonate
• InChIKey: UBLXEEBHYISRFM-UHFFFAOYSA-M
• INCHI: 1S/C10H6O5S.Na/c11-8-5-9(16(13,14)15)6-3-1-2-4-7(6)10(8)12;/h1-5H,(H,13,14,15);/q;+1/p-1
• Isomeric SMILES: C1=CC=C2C(=C1)C(=CC(=O)C2=O)S(=O)(=O)[O-].[Na+]
• WGK Germany: 3
• RTECS: QK1490000
• Molecular Weight: 260.2
• Beilstein: 4169788
• Reaxy-Rn: 4169788
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4169788&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Naphthalenes
      • Subclass Naphthoquinones

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Naphthalenes
• Subclass: Naphthoquinones
• Intermediate Tree Nodes: Not available
• Direct Parent: Naphthoquinones
• Alternative Parents: Quinones Aryl ketones Sulfonyls Organosulfonic acids Organic sodium salts Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic homopolycyclic compounds
• Substituents: Naphthoquinone - Quinone - Aryl ketone - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Sulfonyl - Organosulfonic acid - Ketone - Cyclic ketone - Organic alkali metal salt - Carbonyl group - Organic salt - Organic sodium salt - Hydrocarbon derivative - Organosulfur compound - Organooxygen compound - Organic oxide - Organic oxygen compound - Aromatic homopolycyclic compound
• Description: This compound belongs to the class of organic compounds known as naphthoquinones. These are compounds containing a naphthohydroquinone moiety, which consists of a benzene ring linearly fused to a bezene-1,4-dione (quinone).
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in water (~50 mg/ml), acetone (moderately), alcohol (slightly), and ethanol (slightly). Insoluble in chloroform.carbon disulfide: insoluble
• Melt Point(°C): 289°C
• Molecular Weight: 260.200 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 259.976 Da
• Monoisotopic Mass: 259.976 Da
• Topological Polar Surface Area: 99.700 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 473.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

References

1. Meng Du, Wei Chen, Chen Qian, Zhuo Chen, Guan-Lin Chen, Han-Qing Yu.  (2023)  Using Rayleigh Scattering to Correct the Inner Filter Effect of the Fluorescence Excitation–Emission Matrix.  ANALYTICAL CHEMISTRY,      [PMID:37556363] [10.1021/acs.analchem.3c01093]

2. Bo Gong, Wei Chen, Patrick H.-L. Sit, Xian-Wei Liu, Chen Qian, Han-Qing Yu.  (2023)  Multiple spectroscopic insights into the interaction mechanisms between proteins and humic acid.  WATER RESEARCH,      [PMID:37523922] [10.1016/j.watres.2023.120424]

3. Zhonghua Xue, Hui Wang, Honghong Rao, Nan He, Xiaofen Wang, Xiuhui Liu, Xiaoquan Lu.  (2017)  Amperometric indicator displacement assay for biomarker monitoring: Indirectly sensing strategy for electrochemically inactive sarcosine.  TALANTA,      [PMID:28340776] [10.1016/j.talanta.2017.03.009]

4. Ning Xia, Fengli Gao, Gang Liu, Yong Chang, Lin Liu.  (2024)  Pyrroloquinoline quinone exhibiting peroxidase-mimicking property for colorimetric assays.  ANALYTICA CHIMICA ACTA,      [PMID:39643317] [10.1016/j.aca.2024.343468]

5. Cheng-Ye Zhu, Zhao-Yu Ma, Yu-Ren Xue, Chao Zhang, Hao-Cheng Yang, Hong-Qing Liang, Zhi-Kang Xu.  (2025)  Engineering Vesicle-Like Polyamide Nanofiltration Membrane via Interfacial Polymerization on Shear-Triggered Nanoclay Hydrogel.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202525686]