≥98%(HPLC)(T) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| Pubchem Sid | 488199744 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488199744 |
| Canonical Smiles | C1=CC(=CC=C1OC2=C(C=C(C=C2)N)C(F)(F)F)OC3=C(C=C(C=C3)N)C(F)(F)F |
| IUPAC Name | 4-[4-[4-amino-2-(trifluoromethyl)phenoxy]phenoxy]-3-(trifluoromethyl)aniline |
| InChIKey | LACZRKUWKHQVKS-UHFFFAOYSA-N |
| INCHI | 1S/C20H14F6N2O2/c21-19(22,23)15-9-11(27)1-7-17(15)29-13-3-5-14(6-4-13)30-18-8-2-12(28)10-16(18)20(24,25)26/h1-10H,27-28H2 |
| Isomeric SMILES | C1=CC(=CC=C1OC2=C(C=C(C=C2)N)C(F)(F)F)OC3=C(C=C(C=C3)N)C(F)(F)F |
| Molecular Weight | 428.33 |
| Reaxy-Rn | 10602564 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=10602564&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Diphenylethers |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Diphenylethers |
| Alternative Parents | Diarylethers Trifluoromethylbenzenes Phenoxy compounds Phenol ethers Aniline and substituted anilines Primary amines Organofluorides Hydrocarbon derivatives Alkyl fluorides |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Diphenylether - Diaryl ether - Trifluoromethylbenzene - Phenoxy compound - Phenol ether - Aniline or substituted anilines - Ether - Alkyl fluoride - Primary amine - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Organic oxygen compound - Organic nitrogen compound - Amine - Alkyl halide - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as diphenylethers. These are aromatic compounds containing two benzene rings linked to each other through an ether group. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 H2209179 | Certificate of Analysis | May 20, 2026 | B152522 |
| H2209320 | Certificate of Analysis | May 20, 2026 | B152522 |
| H2209321 | Certificate of Analysis | May 20, 2026 | B152522 |
| G2206479 | Certificate of Analysis | Apr 07, 2026 | B152522 |
| I2503242 | Certificate of Analysis | Jul 12, 2025 | B152522 |
| I2503247 | Certificate of Analysis | Jul 12, 2025 | B152522 |
| I2503248 | Certificate of Analysis | Jul 12, 2025 | B152522 |
| F2405241 | Certificate of Analysis | May 10, 2024 | B152522 |
| F2405242 | Certificate of Analysis | May 10, 2024 | B152522 |
| F2405243 | Certificate of Analysis | May 10, 2024 | B152522 |
| G2020197 | Certificate of Analysis | May 08, 2024 | B152522 |
| G2020195 | Certificate of Analysis | May 08, 2024 | B152522 |
| E2330029 | Certificate of Analysis | Jun 20, 2022 | B152522 |
| Solubility | Soluble in Methanol |
|---|---|
| Melt Point(°C) | 132-136°C |
| Molecular Weight | 428.300 g/mol |
| XLogP3 | 5.400 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 10 |
| Rotatable Bond Count | 4 |
| Exact Mass | 428.096 Da |
| Monoisotopic Mass | 428.096 Da |
| Topological Polar Surface Area | 70.500 Ų |
| Heavy Atom Count | 30 |
| Formal Charge | 0 |
| Complexity | 502.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Hongfei He, Lu Liu, Hongliang Ding, Chuanshen Wang, Ping Yu, Chao Ding, Jixin Zhu, Wei Yang, Yuan Hu, Bin Yu. (2024) Biomimetic Nanostructured Polyimine Aerogels with Graded Porosity, Flame Resistance, Intrinsic Superhydrophobicity, and Closed-Loop Recovery. ACS Nano, [PMID:39681532] [10.1021/acsnano.4c12853] |
| 2. Chunying Min, Yaxiang Su, Hang Yu, Hongyu Liang, Amna Siddique, Zhiwei Xu. (2025) Constructing the fluorine-containing structures for excellent tribological properties of degradable Poly(hexahydrotriazine)s. POLYMER, [PMID:] [10.1016/j.polymer.2025.128691] |
