1-Pyrenebutyric acid - ≥98% , CAS No.3443-45-6

CAS: 3443-45-6 Cat. No.: P106902 Molecular Weight: 288.34 Beilstein Registry Number: 2140554 EC Number: 222-354-7
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
1-Pyrenebutyrate | N-Acetyl-1-naphthylamine | A822234 | AS-30096 | LCZC297 | MLS001181994 | SMR000567713 | PD167333 | 6,7-Dimethoxyphthalide | .gamma.-(3-Pyrenyl)butyric acid | 1-Pyrenebutyric acid | CCG-55743 | Pyrene-1-butyric acid | W-202411 | NSC-1083
Storage
Room temperature
Shipped In
Normal
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Size
Status
Price
Qty
1g
P106902-1g
3
$51.90
5g
P106902-5g
2
$195.90
25g
P106902-25g
1
$262.90
Enter a quantity for the sizes you want to add.
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 21 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
1-Pyrenebutyrate | N-Acetyl-1-naphthylamine | A822234 | AS-30096 | LCZC297 | MLS001181994 | SMR000567713 | PD167333 | 6, 7-Dimethoxyphthalide | .gamma.-(3-Pyrenyl)butyric acid | 1-Pyrenebutyric acid | CCG-55743 | Pyrene-1-butyric acid | W-202411 | NSC-1083
Specifications & Purity
≥98%
Storage
Room temperature
Shipped In
Normal
Purity
≥98%
Names and Identifiers
Pubchem Sid504755126
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504755126
Canonical SmilesC1=CC2=C3C(=C1)C=CC4=C(C=CC(=C43)C=C2)CCCC(=O)O
IUPAC Name4-pyren-1-ylbutanoic acid
InChIKeyQXYRRCOJHNZVDJ-UHFFFAOYSA-N
INCHI1S/C20H16O2/c21-18(22)6-2-3-13-7-8-16-10-9-14-4-1-5-15-11-12-17(13)20(16)19(14)15/h1,4-5,7-12H,2-3,6H2,(H,21,22)
Isomeric SMILES C1=CC2=C3C(=C1)C=CC4=C(C=CC(=C43)C=C2)CCCC(=O)O
WGK Germany 3
Molecular Weight 288.34
Beilstein 2140554
Reaxy-Rn 2140554
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2140554&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassPyrenes
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentPyrenes
Alternative Parents Phenanthrenes and derivatives  Naphthalenes  Monocarboxylic acids and derivatives  Carboxylic acids  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic homopolycyclic compounds
Substituents Pyrene - Phenanthrene - Naphthalene - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aromatic homopolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as pyrenes. These are compounds containing a pyrene moiety, which consists four fused benzene rings, resulting in a flat aromatic system.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (36611 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
FEN1 Tchem Flap endonuclease 1 (12055 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLI Tchem DNA polymerase iota (116820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MBNL1 Tbio Muscleblind-like protein 1 (34431 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAPGEF4 Tchem Rap guanine nucleotide exchange factor 4 (11476 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Luciferin 4-monooxygenase (66902 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NS1 Nonstructural protein 1 (33327 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate TypeDateItem
I2109335Certificate of AnalysisJun 09, 2025 P106902
K2418439Certificate of AnalysisNov 06, 2024 P106902
K2418440Certificate of AnalysisNov 06, 2024 P106902
K2418441Certificate of AnalysisNov 06, 2024 P106902
F2429316Certificate of AnalysisJun 26, 2024 P106902
F2429323Certificate of AnalysisJun 26, 2024 P106902
G2401003Certificate of AnalysisJun 26, 2024 P106902
G2401006Certificate of AnalysisJun 26, 2024 P106902
F2405082Certificate of AnalysisApr 16, 2024 P106902
F2011039Certificate of AnalysisMar 05, 2024 P106902
Chemical and Physical Properties
Melt Point(°C)184-186°C
Molecular Weight288.300 g/mol
XLogP35.100
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count4
Exact Mass288.115 Da
Monoisotopic Mass288.115 Da
Topological Polar Surface Area37.300 Ų
Heavy Atom Count22
Formal Charge0
Complexity418.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Documents & Articles
Citations of This Product
References
1. Yuru Min, Lei Wang, Chenyao Yuan, Honglei Liu, Xiaole Gong, Mengyu Cao, Jiang-Tao Xu, Jingquan Liu.  (2023)  Removal of Formaldehyde and Its Analogues Using a Hybrid Assembly of Pyrene-Modified Hydrazide and rGO: A Negative Carbon Emission and Green Chemical Decomposition Method.  LANGMUIR,      [PMID:37467158] [10.1021/acs.langmuir.3c01452]
2. Hui Xu, Zhiqing Liu, Chenghui Qiao, Xintao Zhang, Qi Zhang, Yuerong Zhang, Yaochen Zheng.  (2022)  High-performance epoxy composites improved by uniformly dispersed and partly thermal reduced graphene oxide sheets.  JOURNAL OF APPLIED POLYMER SCIENCE,  140  (8): (e53502).  [PMID:] [10.1002/app.53502]
3. Hui Dong, Le Zhao, Xu Zhu, Xiuhua Wei, Menghui Zhu, Qingmin Ji, Xueke Luo, Yintang Zhang, Yanli Zhou, Maotian Xu.  (2022)  Development of a novel ratiometric electrochemical sensor for monitoring β-galactosidase in Parkinson's disease model mice.  BIOSENSORS & BIOELECTRONICS,      [PMID:35500308] [10.1016/j.bios.2022.114301]
4. Yujie Yang, Hui Dong, Hewen Yin, Yintang Zhang, Yanli Zhou, Maotian Xu, Xiaobing Wang.  (2022)  Fabrication of nonenzymatic electrochemical interface for ratiometric and simultaneous detection of hydrogen peroxide, dopamine, and ascorbic acid.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2022.107344]
5. Hao Shuai, Zhang He, Sun Xiaoxuan, Zhai Junfeng, Dong Shaojun.  (2020)  A mediator-free self-powered glucose biosensor based on a hybrid glucose/MnO2 enzymatic biofuel cell.  Nano Research,  14  (3): (707-714).  [PMID:] [10.1007/s12274-020-3101-5]
6. Li Chen, Kun Guo, Shi-Lin Zeng, Long Xu, Cheng-Yuan Xing, Sheng Zhang, Bang-Jing Li.  (2020)  Cross-stacking aligned non-woven fabrics with automatic self-healing properties for electromagnetic interference shielding.  CARBON,      [PMID:] [10.1016/j.carbon.2020.02.034]
7. Wei Zhang, Yang Luo, Yang Zhou, Ming Liu, Weitao Xu, Bing Bian, Zhu Tao, Xin Xiao.  (2020)  A highly selective fluorescent chemosensor probe for detection of Fe3+ and Ag+ based on supramolecular assembly of cucurbit[10]uril with a pyrene derivative.  DYES AND PIGMENTS,      [PMID:] [10.1016/j.dyepig.2020.108235]
8. Yi Wang, Yuan Zhong, Li Luo, Xiuhua Li, Tieying Yin, Junli Huang, Xiaojuan Zhang, Wei Wu, Guixue Wang.  (2018)  Synthesis and characterization of pyrene modified polyethylenimine as a novel fluorescent self-reporter for gene condensation.  MATERIALS CHEMISTRY AND PHYSICS,      [PMID:] [10.1016/j.matchemphys.2018.02.027]
9. Zhen Hu, Cheng Wang, Feng Zhao, Xirong Xu, Shuhong Wang, Long Yu, Dayu Zhang, Yudong Huang.  (2017)  Fabrication of a graphene/C60 nanohybrid via γ-cyclodextrin host–guest chemistry for photodynamic and photothermal therapy.  Nanoscale,  (25): (8825-8833).  [PMID:28632263] [10.1039/C7NR02922E]
10. Yanhua Lai, Ping Zhao, Zhan Zhang, Bai Li, Junchen Wu.  (2017)  An effective peptide cargo carrier for the delivery of cisplatin in ovarian cancer cells.  DYES AND PIGMENTS,      [PMID:] [10.1016/j.dyepig.2017.04.025]
11. Yecang Tang, Yi Ding, Ting Wu, Liying Lv, Zhicheng Yan.  (2016)  A turn-on fluorescent probe for Hg2+ detection by using gold nanoparticle-based hybrid microgels.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2016.01.112]
12. Jixian Liu, Zhen Liu, Xiong Luo, Xidan Zong, Jingquan Liu.  (2013)  RAFT Controlled Synthesis of Biodegradable Polymer Brushes on Graphene for DNA Binding and Release.  MACROMOLECULAR CHEMISTRY AND PHYSICS,  214  (20): (2266-2275).  [PMID:] [10.1002/macp.201300338]
13. Sipei Li, Chao Gao.  (2013)  Dendritic molecular brushes: synthesis via sequential RAFT polymerization and cage effect for fluorophores.  Polymer Chemistry,  (16): (4450-4460).  [PMID:] [10.1039/C3PY00546A]
14. Sipei Li, Jin Han, Chao Gao.  (2012)  High-density and hetero-functional group engineering of segmented hyperbranched polymers via click chemistry.  Polymer Chemistry,  (6): (1774-1787).  [PMID:] [10.1039/C2PY20951A]
15. Yu Li, Zhenhua Xiong, Siying Zhang, Long Zhang, Li Sheng, Xingli Ding, Liang Shen, Jingkun Xu, Jinglan Wang, Ge Zhang.  (2024)  Development of fluorescent sensing platform with degradable hydrogel for rapid and ultratrace detection of Cr(VI) in vegetables.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2024.110604]
16. Jiajun Ma, Shengtao Dai, Zongwei Guo, Lei Shang, Yuhui Ao, Lin Jin.  (2024)  Impact of graphene oxide lateral sizes on the mechanical and thermal properties of carbon fiber composites.  POLYMER COMPOSITES,      [PMID:] [10.1002/pc.29087]
17. Xiaole Gong, Jingquan Liu, Changbin Zhang, Mengyu Cao, Yuru Min, Chenyao Yuan, Xiaoxia Hu, Jiangtao Xu, Honglei Liu.  (2024)  Protonated amine and pyrene co-functionalized sodium alginate templated on reduced graphene oxide for highly efficient removal of formaldehyde and acid pollutants.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:38925180] [10.1016/j.ijbiomac.2024.133377]
18. Yunxiao Sang, Chen Feng, Min Liu, Ji-Na Hao, Quan Zhou, Shaoliang Lin, Weihua Zhang, Fang Wang.  (2025)  Amplified and Inverted Circularly Polarized Luminescence with Color Evolution from Multiple-Constituent Coassemblies Directed by Diverse Noncovalent Forces.  ACS Applied Materials & Interfaces,      [PMID:41213874] [10.1021/acsami.5c17022]
19. Liang Shao, Jiaqi Song, Ziyi Wang, Xiaoyu Shan, Wei Zou, Caiting Meng, Yan Zhang, Bin Zhu, Lulu Yang, Xianyi Yu, Jingjing Zou, Yunxuan Li, Dan Su, Guanying Li.  (2026)  Dental Adhesive Peptides Nanonets as Multifunctional Therapy for Caries.  Advanced Healthcare Materials,      [PMID:41560337] [10.1002/adhm.202503597]
20. Tianyi Zhu, Jian Zhang, Danyi He, Yiwen Yang, Hailong Wang, Jianbo Wang, Longhua Guo, Lei Li, Jianrong Chen, Yanbo Zeng.  (2026)  Pyrene-based fluorescent molecularly imprinted polymer for rapid and selective detection of oxytetracycline based on inner filter effect.  Analytical Methods,      [PMID:41665257] [10.1039/D5AY02167G]
21. Jian Kong, Xinlei Zhang, Yiwen Yang, Siyu Ma, Jiantao Bi, Yuangang Li.  (2026)  Conformational effects on the host-guest interaction between amino acids modified pyrene and γ-cyclodextrin.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2026.140199]
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