2,2′-Bipyridine-5,5′-dicarboxylic acid - ≥98% , CAS No.1802-30-8

CAS: 1802-30-8 Cat. No.: B123373 Molecular Weight: 244.2 Beilstein Registry Number: 214282 EC Number: 626-338-4

GRADE & PURITY ≥98%

Synonyms

AM20061692 | 5,5'-Dicarboxy-2,2'-bipyridine | 5,5-Dicarboxy-2,2-bipyridine | 6,6'-Dinicotinic acid, United States Pharmacopeia (USP) Reference Standard | STL556639 | Nicotinic Acid Imp. B (EP); 6,6'-Dinicotinic Acid; 2,2'-Bipyridine-5,5'-dicarboxylic Acid

Storage

Room temperature

Shipped In

Normal

Overview

2,2'-Bipyridine-5,5'-dicarboxylic acid is a nicotinic acid derivative for treatment of hypercholesterolemia and hyperlipidemia and cardiovascular disease.
A nicotinic acid derivative.

Specifications

Synonyms

AM20061692 | 5, 5'-Dicarboxy-2, 2'-bipyridine | 5, 5-Dicarboxy-2, 2-bipyridine | 6, 6'-Dinicotinic acid, United States Pharmacopeia (USP) Reference Standard | STL556639 | Nicotinic Acid Imp. B (EP); 6, 6'-Dinicotinic Acid; 2, 2'-Bipyridine-5, 5'-dicarboxylic Acid

Specifications & Purity

≥98%

Storage

Room temperature

Shipped In

Normal

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 488188561
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488188561
• Canonical Smiles: C1=CC(=NC=C1C(=O)O)C2=NC=C(C=C2)C(=O)O
• IUPAC Name: 6-(5-carboxypyridin-2-yl)pyridine-3-carboxylic acid
• InChIKey: KVQMUHHSWICEIH-UHFFFAOYSA-N
• INCHI: 1S/C12H8N2O4/c15-11(16)7-1-3-9(13-5-7)10-4-2-8(6-14-10)12(17)18/h1-6H,(H,15,16)(H,17,18)
• Isomeric SMILES: C1=CC(=NC=C1C(=O)O)C2=NC=C(C=C2)C(=O)O
• WGK Germany: 3
• Molecular Weight: 244.2
• Beilstein: 214282
• Reaxy-Rn: 214282
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=214282&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Pyridines and derivatives
      • Subclass Bipyridines and oligopyridines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Pyridines and derivatives
• Subclass: Bipyridines and oligopyridines
• Intermediate Tree Nodes: Not available
• Direct Parent: Bipyridines and oligopyridines
• Alternative Parents: Pyridinecarboxylic acids Dicarboxylic acids and derivatives Heteroaromatic compounds Carboxylic acids Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Bipyridine - Pyridine carboxylic acid - Pyridine carboxylic acid or derivatives - Dicarboxylic acid or derivatives - Heteroaromatic compound - Azacycle - Carboxylic acid - Carboxylic acid derivative - Hydrocarbon derivative - Organopnictogen compound - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Organic oxide - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as bipyridines and oligopyridines. These are organic compounds containing two pyridine rings linked to each other.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

P4HA1 Tchem Prolyl 4-hydroxylase subunit alpha-1 (2 Activities)

Discover Target: P4HA1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

P4HTM Tchem Transmembrane prolyl 4-hydroxylase (2 Activities)

Discover Target: P4HTM

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

P4HTM Tchem Hypoxia-inducible factor prolyl 4-hydroxylase (111 Activities)

Discover Target: P4HTM

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EGLN1 Tclin Egl nine homolog 1 (1702 Activities)

Discover Target: EGLN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

P4HA1 Tchem Prolyl 4-hydroxylase subunit alpha-1 (16 Activities)

Discover Target: P4HA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Melt Point(°C): 365°C
• Molecular Weight: 244.200 g/mol
• XLogP3: 0.500
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 244.048 Da
• Monoisotopic Mass: 244.048 Da
• Topological Polar Surface Area: 100.000 Ų
• Heavy Atom Count: 18
• Formal Charge: 0
• Complexity: 302.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

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