Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 27 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
A matabolite of tryptophan and a putative NMDA receptor agonist.
| Canonical Smiles | C1=CC(=C(N=C1)C(=O)O)C(=O)O |
|---|---|
| IUPAC Name | pyridine-2,3-dicarboxylic acid |
| InChIKey | GJAWHXHKYYXBSV-UHFFFAOYSA-N |
| INCHI | 1S/C7H5NO4/c9-6(10)4-2-1-3-8-5(4)7(11)12/h1-3H,(H,9,10)(H,11,12) |
| Isomeric SMILES | C1=CC(=C(N=C1)C(=O)O)C(=O)O |
| WGK Germany | 3 |
| RTECS | US7967250 |
| Alternate CAS | 339155-13-4 |
| Molecular Weight | 167.12 |
| Beilstein | 137110 |
| Reaxy-Rn | 137110 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=137110&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Pyridines and derivatives |
| Subclass | Pyridinecarboxylic acids and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Pyridinecarboxylic acids |
| Alternative Parents | Dicarboxylic acids and derivatives Heteroaromatic compounds Carboxylic acids Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Pyridine carboxylic acid - Dicarboxylic acid or derivatives - Heteroaromatic compound - Azacycle - Carboxylic acid - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aromatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as pyridinecarboxylic acids. These are compounds containing a pyridine ring bearing a carboxylic acid group. |
| External Descriptors | pyridinedicarboxylic acid |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Melt Point(°C) | 188-190°C |
|---|---|
| Molecular Weight | 167.120 g/mol |
| XLogP3 | 0.200 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 2 |
| Exact Mass | 167.022 Da |
| Monoisotopic Mass | 167.022 Da |
| Topological Polar Surface Area | 87.500 Ų |
| Heavy Atom Count | 12 |
| Formal Charge | 0 |
| Complexity | 204.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Huilin Li, Jingying Yang, Xiaochun Hu, Ran Han, Shuo Wang, Mingfei Pan. (2023) Portable smartphone-assisted fluorescence-colorimetric multidimensional immunosensing microarray based on NH2-UiO-66@PtNPs multifunctional composite for efficient and visual detection of amantadine. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2023.145401] |
| 2. Yakun Sun, Long Li, Xinxu Li, Ya-Nan Feng, Fei-Fei Chen, Lingyun Li, Yan Yu. (2023) Regulating Activity and Selectivity of Photocatalytic CO2 Reduction on Cobalt by Rare Earth Compounds. ACS Applied Materials & Interfaces, [PMID:36949018] [10.1021/acsami.2c20402] |
| 3. Nan Jiang, Hongyan Liu, Guodong Zhao, Heyi Li, Shuo Yang, Xianlin Xu, Xupin Zhuang, Bowen Cheng. (2023) Aramid nanofibers supported metal-organic framework aerogel for protection of chemical warfare agent. JOURNAL OF COLLOID AND INTERFACE SCIENCE, [PMID:36863176] [10.1016/j.jcis.2023.02.105] |
| 4. Shengnan Yin, Changlun Tong. (2021) Europium(III)-Modified Silver Nanoparticles as Ratiometric Colorimetric and Fluorescent Dual-Mode Probes for Selective Detection of Dipicolinic Acid in Bacterial Spores and Lake Waters. ACS Applied Nano Materials, [PMID:] [10.1021/acsanm.1c00838] |
| 5. Ru-Ru Gao, Wei Dong. (2020) ATP and lanthanide ions derived coordination polymer nanoparticles as a novel family of versatile materials: Color-tunable emission, artificial tongues and logic devices. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2020.105753] |
| 6. Hao Chen, Chunlong Dai, Yanan Li, Renming Zhan, Min-Qiang Wang, Bingshu Guo, Youquan Zhang, Heng Liu, Maowen Xu, Shu-juan Bao. (2018) An excellent full sodium-ion capacitor derived from a single Ti-based metal–organic framework. Journal of Materials Chemistry A, 6 (48): (24860-24868). [PMID:] [10.1039/C8TA09072F] |
| 7. Shi-Fan Xue, Jing-Fei Zhang, Zi-Han Chen, Xin-Yue Han, Min Zhang, Guoyue Shi. (2018) Multifunctional fluorescent sensing of chemical and physical stimuli using smart riboflavin-5′-phosphate/Eu3+ coordination polymers. ANALYTICA CHIMICA ACTA, [PMID:29475476] [10.1016/j.aca.2018.01.038] |
| 8. Qi-Xian Wang, Shi-Fan Xue, Zi-Han Chen, Shi-Hui Ma, Shengqiang Zhang, Guoyue Shi, Min Zhang. (2017) Dual lanthanide-doped complexes: the development of a time-resolved ratiometric fluorescent probe for anthrax biomarker and a paper-based visual sensor. BIOSENSORS & BIOELECTRONICS, [PMID:28324858] [10.1016/j.bios.2017.03.027] |
| 9. Shuo Li, Yingxiao Du, Xinyan Zhu, Ningning Zhao, Lei Dai, Bin Li, Zekun Zhang, Wei Meng, Jing Zhu, Ling Wang, Zhangxing He. (2024) Constructing high-performance zinc metal anodes based on an amino-functionalized highly three-dimensional porous structure interface layer. Journal of Materials Chemistry A, [PMID:] [10.1039/D4TA06942K] |
| 10. Ming-Li Ma, Le-Chen Zheng, Rui Li, Yabo Xie. (2025) Facile and Versatile Construction of MOF@COF Heterostructures in Atmospheric Air for Enhanced CO2 Photoreduction. CRYSTENGCOMM, [PMID:] [10.1039/D4CE01293C] |
| 11. Kaixiong Zhao, Weizhao Hu, Yanbei Hou. (2024) Nanoconfinement-Enhanced Fire Safety and Mechanical Properties of Polylactic Acid with Nanocerium Metal–Organic Frameworks. ACS Applied Materials & Interfaces, [PMID:39164204] [10.1021/acsami.4c09184] |
| 12. Bing He, Ying-Jie Wang, Xuefeng Bai, He Bian, Yabo Xie, Rui Li, Jian-Rong Li. (2024) Rational construction of MOF-on-MOF heterojunction with an array of flexible two-dimensional microsheets for efficient CO2 photoreduction. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2024.149000] |
| 13. Huifang Wu, Qiqi Wang, Lingfeng Zhu, Haoliang Zhang, Lizhong Liu. (2025) Regulating the aromatic structure in carbon dots to enhance the internal filter effect for sensitive on-site monitoring of anthrax biomarkers. TALANTA, [PMID:40031139] [10.1016/j.talanta.2025.127854] |
| 14. Xiaohui Niu, Yuewei Wang, Xing Yang, Yongqi Liu, Mei Yuan, Jianying Zhang, Hongxia Li, Kunjie Wang. (2025) Tailoring Chirality and Optimizing Enantioselective Recognition in Strategic Defect Engineering of Chiral Metal–Organic Frameworks. ANALYTICAL CHEMISTRY, [PMID:39832794] [10.1021/acs.analchem.4c06114] |
| 15. Ai-Hui Cao, Xin-Tai Su, Min Zhang, Qi-Long Zhu. (2025) Static Internal Electric Field in Heterojunctions Composed of O–C3N4 Nanosheets Decorated with NH2-MIL-101(Cr) Nanoparticles for Photocatalytic Hydrogen Evolution. ACS Applied Nano Materials, [PMID:] [10.1021/acsanm.5c02685] |
| 16. Jingling Gong, Bin Xiang, Ruirui Jin, Zhaoyang Li, Weimin Liu, Jian Li. (2025) Robust peony-like Cu3(PO4)2/UiO-66-NH2/PVA membranes with exceptional anti-fouling performance for high flux emulsion separation. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2025.134915] |
| 17. Haoran Yin, Ziyan Lin, Lixia Wang, Yong Huang, Tayirjan Taylor Isimjan, Xiulin Yang. (2025) Leveraging ligand push-pull effects in Ni-based MOFs for optimized lattice oxygen activation and superior water oxidation. APPLIED CATALYSIS B-ENVIRONMENTAL, [PMID:] [10.1016/j.apcatb.2025.125610] |
| 18. Muhammad Kashif Majeed, Arshad Hussain, Muhammad Akram, M.Umar Majeed, Muhammad Arshad, Adil Saleem, Rashid Iqbal. (2025) Linker-Functionalized Zr-Based UiO-66 Metal-Organic Frameworks: Tuning Acidity for Enhanced Catalytic Dimerization of Cyclohexanone. ChemNanoMat, [PMID:] [10.1002/cnma.202500026] |
| 19. Yiqun Liu, Zhengyan Qu, Jiuxuan Zhang, Hong Jiang, Zhenchen Tang, Weihong Xing, Rizhi Chen. (2025) Hydrogenation of Nitrophenol via Nickel-Based Catalytic Membranes with Engineered Surface Affinity. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, [PMID:] [10.1021/acs.iecr.5c01244] |
| 20. Hao Su, Si-qi Yang, Qiu-ling Zhang, Wei-peng Qiu, Lin Luo, Ya-li Zhao, Zhen-lin Xu, Hong Wang, Peng Wen. (2025) Ratiometric fluorescent probe based on amino-functionalized MOF for on-site glyphosate detection via smartphone-integrated hydrogel platform. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.115971] |
| 21. Mingjun Xiao, Huizhen Sun, Hong Zhang, Haibin Tang. (2025) Preparation and Regulation of a Platinum Nanoparticle Embedded Titanium Dioxide Material. PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION, [PMID:] [10.1002/ppsc.202500170] |
| 22. Hongbo Li, Hao Wang, Meiyi Cao, Xing Tong, Shuo Wang, Mingfei Pan. (2025) Dual-mode fluorescence and colorimetric immunosensing platform based on Au/Pt NPs@NH2-MIL-53(Al) composite for effective detection of enrofloxacin in animal-derived foods. FOOD CHEMISTRY, [PMID:41397316] [10.1016/j.foodchem.2025.147463] |
| 23. Du Boyu, Qi Xianjin, Li Yongkui, Pan Hongyan, Lei Wenya, Yan Kai. (2025) Structural Defect Construction of Acid and Iron Dual-Modified UiO-66-NH2 for Enhanced Arsenic Capture in Wastewater. JOM, [PMID:] [10.1007/s11837-025-08058-8] |
| 24. Haicheng Liu, Wenhao Zhang, Chuang Zhang, Shuwen Wang. (2026) Bismuth oxyhalide modified bimetallic Ce/Zr-MOF to construct Z-scheme heterojunction for enhanced visible light photocatalytic degradation of typical antibiotics. JOURNAL OF ALLOYS AND COMPOUNDS, [PMID:] [10.1016/j.jallcom.2026.186211] |
| 25. Zhou Donglai, Yang Ruyu, Jia Zijin, Cai Yuhai, Zhao Luyuan, Guo Lulu, Ye Guilin, Wang Song, Chen Linjiang, Liu Daobin, Smith Pieter E. S., Huang Yan, Zhu Qing, Jiang Jun. (2026) A practical inverse design approach for high-entropy catalysts using generative AI. Nature Synthesis, [PMID:] [10.1038/s44160-025-00983-5] |
| 26. Yanhua Liu, Yunpeng Luo, Geoffrey I.N. Waterhouse, Zhiming Zhang, Liangmin Yu. (2026) Heterojunction engineering in titanium dioxide/NH2-MIL-125(titanium)/polyaniline cathodes enhances visible light-driven Photoelectrocatalytic rhodamine B degradation. Journal of Water Process Engineering, [PMID:] [10.1016/j.jwpe.2026.109711] |
| 27. Shi Lei, Liu Yinpeng, Liu Hongyan, Li Yafang, Zhuang Xupin, Jiang Nan. (2026) Metal–Organic Framework-Immobilized Aramid Nanofibers Aerogels for Chemical Warfare Agent Protection. FIBERS AND POLYMERS, [PMID:] [10.1007/s12221-026-01392-x] |