≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 4 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| Pubchem Sid | 504752257 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504752257 |
| Canonical Smiles | C1=CC(=C(C=C1[N+](=O)[O-])Cl)O |
| IUPAC Name | 2-chloro-4-nitrophenol |
| InChIKey | BOFRXDMCQRTGII-UHFFFAOYSA-N |
| INCHI | 1S/C6H4ClNO3/c7-5-3-4(8(10)11)1-2-6(5)9/h1-3,9H |
| Isomeric SMILES | C1=CC(=C(C=C1[N+](=O)[O-])Cl)O |
| WGK Germany | 3 |
| RTECS | SK5075000 |
| UN Number | 2811 |
| Molecular Weight | 173.55 |
| Beilstein | 6240 |
| Reaxy-Rn | 2046372 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2046372&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Phenols |
| Subclass | Nitrophenols |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Nitrophenols |
| Alternative Parents | Nitrobenzenes O-chlorophenols Nitroaromatic compounds Chlorobenzenes 1-hydroxy-2-unsubstituted benzenoids Aryl chlorides Propargyl-type 1,3-dipolar organic compounds Organic oxoazanium compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organochlorides Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Nitrophenol - Nitrobenzene - Nitroaromatic compound - 2-halophenol - 2-chlorophenol - 1-hydroxy-2-unsubstituted benzenoid - Chlorobenzene - Halobenzene - Aryl chloride - Aryl halide - Monocyclic benzene moiety - Organic nitro compound - C-nitro compound - Organic oxoazanium - Allyl-type 1,3-dipolar organic compound - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Organochloride - Organohalogen compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organonitrogen compound - Organooxygen compound - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as nitrophenols. These are compounds containing a nitrophenol moiety, which consists of a benzene ring bearing both a hydroxyl group and a nitro group on two different ring carbon atoms. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 D2622062 | Certificate of Analysis | May 06, 2026 | C104236 |
| D2617059 | Certificate of Analysis | Apr 23, 2026 | C104236 |
| E2614030 | Certificate of Analysis | Apr 23, 2026 | C104236 |
| A1928035 | Certificate of Analysis | Mar 20, 2026 | C104236 |
| J2023144 | Certificate of Analysis | Feb 05, 2026 | C104236 |
| D2017081 | Certificate of Analysis | Aug 15, 2025 | C104236 |
| L2129107 | Certificate of Analysis | Oct 09, 2023 | C104236 |
| L2129108 | Certificate of Analysis | Oct 09, 2023 | C104236 |
| L2129165 | Certificate of Analysis | Oct 09, 2023 | C104236 |
| L2129167 | Certificate of Analysis | Oct 09, 2023 | C104236 |
| K2129327 | Certificate of Analysis | Sep 15, 2023 | C104236 |
| D2327050 | Certificate of Analysis | Nov 13, 2021 | C104236 |
| E2323019 | Certificate of Analysis | Nov 13, 2021 | C104236 |
| Solubility | Slightly Soluble in water. |
|---|---|
| Sensitivity | Moisture sensitive. |
| Melt Point(°C) | 106-112°C |
| Molecular Weight | 173.550 g/mol |
| XLogP3 | 2.300 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 0 |
| Exact Mass | 172.988 Da |
| Monoisotopic Mass | 172.988 Da |
| Topological Polar Surface Area | 66.100 Ų |
| Heavy Atom Count | 11 |
| Formal Charge | 0 |
| Complexity | 158.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Jiayue Dong, Peizeng Yang, Jing Chen, Yuefei Ji, Junhe Lu. (2022) Nitrophenolic byproducts formation during sulfate radical oxidation and their fate in simulated drinking water treatment processes. WATER RESEARCH, [PMID:36088770] [10.1016/j.watres.2022.119054] |
| 2. Feng Li, Qi-Le Li, Lei Hu, Hong-Yu Zhu, Wen-Juan Wang, Fen-Ying Kong, Heng-Ye Li, Zhong-Xia Wang, Wei Wang. (2021) Ratiometric detection of p-nitrophenol and its derivatives using a dual-emissive neuron cell-like carbonized probe based on a π⋯π stacking quenching mechanism. ANALYST, 146 (14): (4566-4575). [PMID:34152330] [10.1039/D1AN00891A] |
| 3. Fu Yang, Jin Wang, Shuying Gao, Shijian Zhou, Yan Kong. (2020) Record-high catalytic hydrogenated activity in nitroarenes reduction derived from in-situ nascent active metals enabled by constructing bimetallic phosphate. Molecular Catalysis, [PMID:] [10.1016/j.mcat.2020.110873] |
| 4. Yanhong Zheng, Zeyu Song, Muwei Huang, Cancan Li, Chunke Nong, Tinghao Jiang, Zhanji Li, Zhongsheng Yi. (2025) Elucidating thyroid hormone transport proteins disruption by nitrophenols through computational and spectroscopic analysis. BIOPHYSICAL CHEMISTRY, [PMID:39987709] [10.1016/j.bpc.2025.107415] |
