2-Hydroxy-1,4-naphthoquinone - ≥98% , CAS No.83-72-7

Name: 2-Hydroxy-1,4-naphthoquinone - ≥98% , CAS No.83-72-7
SKU: H121701
Availability: InStock

CAS: 83-72-7 Cat. No.: H121701 Formula: C₁₀H₆O₃ Molecular Weight: 174.15 Beilstein Registry Number: 1565260 EC Number: 201-496-3

8 Citations COA

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2-Hydroxy-1,4-naphthoquinone - ≥98% CAS No(83-72-7) by Aladdin Scientific

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AVAILABLE TO ORDER

GRADE & PURITY ≥98%

Synonyms

Storage

Room temperature

Shipped In

Normal

Overview Specifications Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Documents & Articles Citations of This Product Solution Calculators Reviews

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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 8 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

2-Hydroxy-1,4-naphthoquinone is one among the forensic reagents used for fingerprint detection 2-Hydroxy-1,4-naphthoquinone, produced from Lawsonia inermis, is an orange dye. It belongs to the class of naphthoquinone dyes. 2-Hydroxy-1,4-naphthoquinone is used to dye hair and to color textiles. It has antibacterial, antifungal, anti-inflammatory, antiviral and antineoplastic properties. 2-Hydroxy-1,4-naphthoquinone inhibits tumor cell growth. It stimulates the production of reactive oxygen species (ROS).[
An antimicrobial antioxidant dye isolated from Henna.

2-Hydroxy-1,4-naphthoquinone is used for preparing decorative hair and skin dyes. 2-Hydroxy-1,4-naphthoquinone also demonstrates antimicrobial and antioxidant effects. It also suppress the formation of hydrogen peroxide and superoxide radical anion by aldehyde oxidase-catalyzed reactions.

Specifications

Synonyms

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

2-Hydroxy-1,4-naphthoquinone (Lawsone) is a naphthoquinone dye isolated from leaves of Lawsonia inermis, the Henna plant used for preparing decorative hair and skin dyes. In addition to strong light interaction which underlies the aesthetic properties of

Storage

Room temperature

Shipped In

Normal

Purity

≥98%

Names and Identifiers

Pubchem Sid

488180149

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488180149

Canonical Smiles

C1=CC=C2C(=C1)C(=CC(=O)C2=O)O

IUPAC Name

4-hydroxynaphthalene-1,2-dione

InChIKey

WVCHIGAIXREVNS-UHFFFAOYSA-N

INCHI

1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H

Isomeric SMILES

C1=CC=C2C(=C1)C(=CC(=O)C2=O)O

WGK Germany

RTECS

QL8200000

Molecular Weight

174.15

Beilstein

1565260

Reaxy-Rn

2575949

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2575949&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Naphthalenes
    - Subclass Naphthoquinones

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Naphthalenes
Subclass	Naphthoquinones
Intermediate Tree Nodes	Not available
Direct Parent	Naphthoquinones
Alternative Parents	Naphthols and derivatives Quinones Aryl ketones Vinylogous acids Enols Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic homopolycyclic compounds
Substituents	Naphthoquinone - 1-naphthol - Aryl ketone - Quinone - Vinylogous acid - Cyclic ketone - Ketone - Enol - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aromatic homopolycyclic compound
Description	This compound belongs to the class of organic compounds known as naphthoquinones. These are compounds containing a naphthohydroquinone moiety, which consists of a benzene ring linearly fused to a bezene-1,4-dione (quinone).
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D Structure

Associated Targets(Human)

ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)

Discover Target: ALOX5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

VDR Tclin Vitamin D receptor (26531 Activities)

Discover Target: VDR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TYR Tclin Tyrosinase (717 Activities)

Discover Target: TYR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DHODH Tclin Dihydroorotate dehydrogenase (2737 Activities)

Discover Target: DHODH

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

P2RX7 Tchem P2X purinoceptor 7 (5534 Activities)

Discover Target: P2RX7

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MMP3 Tchem Matrix metalloproteinase 3 (3433 Activities)

Discover Target: MMP3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MMP8 Tchem Matrix metalloproteinase 8 (1942 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTPN22 Tchem Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (1215 Activities)

Discover Target: PTPN22

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MMP1 Tchem Matrix metalloproteinase-1 (7046 Activities)

Discover Target: MMP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LoVo (4724 Activities)

Lot Number	Certificate Type	Date	Item
A2218482	Certificate of Analysis	Oct 29, 2025	H121701
F2109070	Certificate of Analysis	Mar 04, 2025	H121701
F2109069	Certificate of Analysis	Mar 04, 2025	H121701
H2612697	Certificate of Analysis	Nov 13, 2024	H121701
H2612696	Certificate of Analysis	Nov 13, 2024	H121701
H2612692	Certificate of Analysis	Nov 13, 2024	H121701
C2512461	Certificate of Analysis	Oct 10, 2024	H121701
K2024275	Certificate of Analysis	Sep 11, 2024	H121701
D2407327	Certificate of Analysis	Mar 15, 2024	H121701
C2409145	Certificate of Analysis	Mar 05, 2024	H121701
C2409146	Certificate of Analysis	Mar 05, 2024	H121701
C2409143	Certificate of Analysis	Mar 05, 2024	H121701
C2409144	Certificate of Analysis	Mar 05, 2024	H121701
I2328430	Certificate of Analysis	Sep 14, 2023	H121701
I2328073	Certificate of Analysis	Sep 14, 2023	H121701
I2328042	Certificate of Analysis	Sep 14, 2023	H121701
I2328041	Certificate of Analysis	Sep 14, 2023	H121701
G2320803	Certificate of Analysis	Jul 15, 2023	H121701
G2320811	Certificate of Analysis	Jul 15, 2023	H121701
G2320810	Certificate of Analysis	Jul 15, 2023	H121701
G2320800	Certificate of Analysis	Jul 15, 2023	H121701
E2312444	Certificate of Analysis	May 06, 2023	H121701
E2312242	Certificate of Analysis	May 06, 2023	H121701
E2312221	Certificate of Analysis	May 06, 2023	H121701
E2312187	Certificate of Analysis	May 06, 2023	H121701
B2309154	Certificate of Analysis	Feb 18, 2023	H121701
B2309142	Certificate of Analysis	Feb 14, 2023	H121701
B2309141	Certificate of Analysis	Feb 14, 2023	H121701
H2202168	Certificate of Analysis	Jul 03, 2022	H121701
H2202169	Certificate of Analysis	Jul 03, 2022	H121701
A2218549	Certificate of Analysis	Dec 25, 2021	H121701
A2218548	Certificate of Analysis	Dec 25, 2021	H121701
A2218446	Certificate of Analysis	Dec 25, 2021	H121701

Solubility	Soluble in water. 2 g/L at 20°C
Melt Point(°C)	193°C
Molecular Weight	174.150 g/mol
XLogP3	0.900
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	0
Exact Mass	174.032 Da
Monoisotopic Mass	174.032 Da
Topological Polar Surface Area	54.400 Å²
Heavy Atom Count	13
Formal Charge	0
Complexity	291.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

2-Hydroxy-1,4-naphthoquinone - ≥98% , CAS No.83-72-7

Storage & shipping

Quality documents

Literature proof

Overview

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

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📚 Citations by Application

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