GRADE & PURITYMoligand™?Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.≥98%
Moligand™,≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Linsidomine hydrochloride (SIN-1 chloride) is a spontaneous ROS/RNS generator and peroxynitrite donor. Linsidomine hydrochloride is a vasodilator and platelet aggregation inhibitor. Linsidomine hydrochloride induces oxidative stress-induced chondrocyte apoptosis and necrosis. Linsidomine hydrochloride inhibits the migration, proliferation and neointima formation of vascular smooth muscle cells by inhibiting the expression of annexin A2. In addition, low doses of Linsidomine hydrochloride shows protective effects on Zn2+ treated nerve cells.
SIN-1 chloride is an active metabolite of molsidomine, which is a potent vasorelaxant and inhibitor of platelet aggregation. It produces both NO and superoxide and can therefore be used to generate peroxynitrite under physiological conditions. SIN-1 decre
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
MODULATOR
Note
If possible, you try to configure the solution on the same day and use it on the same day. However, if you need to prepare a stock solution in advance, we recommend that you store aliquots of the solution in sealed vials at -20°C. Generally, they can be used for up to one month. Before use and before opening the sample vial, we recommend that you allow your product to equilibrate at room temperature for at least 1 hour.
1.Yu Lan, Haixia Zhang, Ruichen Xie, Kecheng Li, Feiran Xie, Peihong Xiao, Li Jiang. (2024) An endoplasmic reticulum-targeted NIR fluorescent nanoprobe for early diagnosis of glaucoma in vivo. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:][10.1016/j.snb.2024.135441]
2.Qiwen Peng, Fangbing Wang, Yi Ru, Yongheng Zhang, Guoyue Shi, Min Zhang. (2025) Laser-written nanometal-doped graphene on paper for Alzheimer’s multi-target sensing. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:][10.1016/j.snb.2025.138973]
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Reviews
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Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
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