4-Carboxyphenylboronic acid (contains varying amounts of Anhydride) - ≥97% , CAS No.14047-29-1

CAS: 14047-29-1 Cat. No.: C101099 Molecular Weight: 165.94 Beilstein Registry Number: 3031088 EC Number: 604-189-6

GRADE & PURITY ≥97%

Synonyms

4-Carboxybenzeneboronic Acid (contains varying amounts of Anhydride) | 4-Boronobenzoic acid(contains varying amounts of Anhydride)

Storage

Protected from light,Room temperature

Shipped In

Normal

Overview

Reactant involved in:
Condensation reactions with stabilizer chains at the surface of polystyrene latex
Suzuki coupling reactions
Esterification
Derivatization of polyvinylamine
Synthesis of isotopically labeled mercury
Functionalization of poly-SiNW for detection of dopamine
Reagent used for
Suzuki-Miyaura cross-coupling 
Induction of pH sensitivity on fluorescence lifetime of quantum dots by NIR fluorescent dyes 
Bio-supported palladium nanoparticles as phosphine-free catalyst for Suzuki reaction in water 
Chan-Lam-type Copper (Cu)-catalyzed S-arylation with aryl boronic acids at room temperature 
Reagent used in Preparation of
Isoquinolones via regioselective Suzuki-Miyaura cross-coupling and tandem palladium-catalyzed intramolecular aminocarbonylation and annulation 
Amprenavir-based P1-substituted bi-aryl derivatives as ultra-potent HIV-1 protease inhibitors 
Phenols via visible-light initiated aerobic oxidative hydroxylation of arylboronic acids using air as oxidant catalyzed by Ruthenium (Ru)-complex 
Glucose sensitive boronic acid-bearing block copolymers 
Trisulfonated calixarene upper-rim sulfonamido derivatives and their complexation with the trimethyllysine epigenetic mark

Specifications

Synonyms

4-Carboxybenzeneboronic Acid (contains varying amounts of Anhydride) | 4-Boronobenzoic acid(contains varying amounts of Anhydride)

Specifications & Purity

≥97%

Storage

Protected from light, Room temperature

Shipped In

Normal

Purity

≥97%

Names and Identifiers

• Pubchem Sid: 488189428
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488189428
• Canonical Smiles: B(C1=CC=C(C=C1)C(=O)O)(O)O
• IUPAC Name: 4-boronobenzoic acid
• InChIKey: SIAVMDKGVRXFAX-UHFFFAOYSA-N
• INCHI: 1S/C7H7BO4/c9-7(10)5-1-3-6(4-2-5)8(11)12/h1-4,11-12H,(H,9,10)
• Isomeric SMILES: B(C1=CC=C(C=C1)C(=O)O)(O)O
• WGK Germany: 2
• RTECS: CY8925000
• Molecular Weight: 165.94
• Beilstein: 3031088
• Reaxy-Rn: 3031088
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3031088&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Benzene and substituted derivatives
      • Subclass Benzoic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Benzene and substituted derivatives
• Subclass: Benzoic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Benzoic acids
• Alternative Parents: Benzoyl derivatives Boronic acids Organic metalloid salts Monocarboxylic acids and derivatives Carboxylic acids Organooxygen compounds Organoboron compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Benzoic acid - Benzoyl - Boronic acid - Boronic acid derivative - Organic metalloid salt - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organic salt - Organooxygen compound - Organoboron compound - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as benzoic acids. These are organic Compounds containing a benzene ring which bears at least one carboxyl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

Discover Target: APEX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

ampC Beta-lactamase AmpC (62480 Activities)

Discover Target: ampC

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Staphylococcus aureus (210822 Activities)

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Escherichia coli (133304 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Enterococcus faecium (13803 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Enterococcus faecalis (29875 Activities)

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Subtilisin (36 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

norA Quinolone resistance protein norA (2171 Activities)

Discover Target: norA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

dac D-alanyl-D-alanine carboxypeptidase (132 Activities)

Discover Target: dac

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

dapE Succinyl-diaminopimelate desuccinylase (42 Activities)

Discover Target: dapE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

pbpX Penicillin-binding protein 2X (99 Activities)

Discover Target: pbpX

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Solubility: DMSO (Slightly), Methanol (Slightly)
• Sensitivity: light sensitive
• Melt Point(°C): 220°C
• Molecular Weight: 165.940 g/mol
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 166.044 Da
• Monoisotopic Mass: 166.044 Da
• Topological Polar Surface Area: 77.800 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 163.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

XLogP3

References

1. Yuan Gu, Yanjun Cai, Yige Kou, Erzhuo Cheng, Hanjie Bi, Min Hu, Songyao Wu, Yong Jiang, Jingxi Zhang, Qingting Wu, Yunyi Li, Bin Yang.  (2023)  Construction of multifunctional targeted nano-prodrugs based on PAMAM dendrimers for tumor therapy.  EUROPEAN POLYMER JOURNAL,      [PMID:] [10.1016/j.eurpolymj.2023.112486]

2. Chenhui Lu, Haodong Wei, Lizhi Xu, Wen-Long Wang, Cheng Yang, Xueli Shi, Hui Gao, Yong-Wei Feng, Jianzhong Zhou, Yi Zhang.  (2023)  Enrichment of sialic acid-containing casein glycomacropeptide in protein hydrolysates using phenylboronic acid-functionalized mesoporous silica nanoparticles.  TALANTA,      [PMID:37708769] [10.1016/j.talanta.2023.125174]

3. Zhi Hu, Shucheng Liu, Nana Tang, Xuan Zhang, Jianming Pan.  (2023)  Hierarchically porous MOFs self-supporting copolymers for ultrafast transport and precise recognition of flavonoids: A triple interfacial crosslinking strategy based on microreactors.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2023.124819]

4. Lulu Wang, Fan Qi, Luopeng Bi, Jiao Yan, Xiaoqing Han, Yanjing Wang, Panpan Song, Yanbo Wang, Haiyuan Zhang.  (2023)  Targeted hollow pollen silica nanoparticles for enhanced intravesical therapy of bladder cancer.  Biomaterials Science,  11  (14): (4948-4959).  [PMID:37314787] [10.1039/D3BM00631J]

5. Tingting He, Lu Wang, Shuangquan Gou, Lu Lu, Genhua Liu, Kui Wang, Yulu Yang, Qiaojian Duan, Wenbo Geng, Peng Zhao, Zhong Luo, Kaiyong Cai.  (2023)  Enhanced Immunogenic Cell Death and Antigen Presentation via Engineered Bifidobacterium bifidum to Boost Chemo-immunotherapy.  ACS Nano,      [PMID:37212750] [10.1021/acsnano.2c11474]

6. Jia Yuanbo, Hu Jiahui, An Keli, Zhao Qiang, Dang Yang, Liu Hao, Wei Zhao, Geng Songmei, Xu Feng.  (2023)  Hydrogel dressing integrating FAK inhibition and ROS scavenging for mechano-chemical treatment of atopic dermatitis.  Nature Communications,  14  (1): (1-14).  [PMID:37120459] [10.1038/s41467-023-38209-x]

7. Junjie Deng, Zhihao Guan, Donglei Fu, Yuewei Zheng, Zhengjie Chen, Houbin Li, Xinghai Liu.  (2023)  Excitation-Dependent Long Afterglow Room-Temperature Phosphorescence Material Activated by Doping Boric Acid Matrix.  Advanced Optical Materials,  11  (14): (2300207).  [PMID:] [10.1002/adom.202300207]

8. Yangyang Lu, Haojie Yu, Li Wang, Di Shen, Jian Liu.  (2023)  Preparation of phenylboronic acid‐based glucose-responsive hydrogels and microneedles for regulated delivery of insulin.  EUROPEAN POLYMER JOURNAL,      [PMID:] [10.1016/j.eurpolymj.2023.112061]

9. Fang Zhu, Jianhua Zhang, Jian Zhong, Tianyou Wang, Yiwen Li, Zhipeng Gu.  (2023)  Natural polyphenol-based nanoparticles for the treatment of iron-overload disease.  JOURNAL OF CONTROLLED RELEASE,      [PMID:36813037] [10.1016/j.jconrel.2023.02.027]

10. Yaqing Liu, Xiaoxiao Lv, Ying Song, Qi Ao, Bolei Yuan, Tingting Huang, Xinglai Tong, Jun Tang.  (2023)  Sustainable and Tough MXene Hydrogel Based on Interlocked Structure for Multifunctional Sensing.  ACS Sustainable Chemistry & Engineering,      [PMID:] [10.1021/acssuschemeng.2c06939]

11. Jinyue Chai, Xue Chen, Chengcheng Jin, Fang Chai, Miaomiao Tian.  (2023)  Selective enrichment of Rutin in sunscreen by boronate affinity molecularly imprinted polymer prior to determination by high performance liquid chromatography.  BIOCHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.bej.2023.108811]

12. Jiebing Yang, Jiayuan Zhang, Jiakai Xing, Zhiyuan Shi, Haobo Han, Quanshun Li.  (2023)  Inhibition of proliferation and migration of tumor cells through phenylboronic acid-functionalized polyamidoamine-mediated delivery of a therapeutic DNAzyme Dz13.  International Journal of Nanomedicine,      [PMID:31496692] [10.2147/IJN.S211744]

13. Jian Song, Kaiyu He, Bingcong Xing, Yong Pei, Dingnan Wang, Yang Wang, Shiyan Li, Jie Li, Weiwei Huan, Yiming Zhang, Bruce. D. Hammock.  (2022)  Rapid Measurement of Residual Kanamycin Using Highly Specific Biomimetic Recognition Paper-Based Chip.  ANALYTICAL CHEMISTRY,      [PMID:36458677] [10.1021/acs.analchem.2c03932]

14. Jiamei Li, Yang Zhou, Jiaqi Liu, Xiaotong Yang, Kai Zhang, Lei Lei, Haili Hu, Huilin Zhang, Liang Ouyang, Huile Gao.  (2022)  Metal-phenolic networks with ferroptosis to deliver NIR-responsive CO for synergistic therapy.  JOURNAL OF CONTROLLED RELEASE,      [PMID:36272661] [10.1016/j.jconrel.2022.10.025]

15. Yajie Zhong, Farzad Seidi, Yilin Wang, Ling Zheng, Yongcan Jin, Huining Xiao.  (2022)  Injectable chitosan hydrogels tailored with antibacterial and antioxidant dual functions for regenerative wound healing.  CARBOHYDRATE POLYMERS,      [PMID:36241280] [10.1016/j.carbpol.2022.120103]

16. Yanqin Wang, Yu Zhu, Xuehui Zhang, Fengbo Zhu, Yi-Xian Qin, Weiyi Chen, Qiang Zheng.  (2022)  Luminescent composite organohydrogels with Fe3+, pH, and glucose-dependent shape memory behavior accompanied with diverse fluorescence variation.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2022.137930]

17. Zheng Liu, Tao Liu, Weidong Gu, Xilin Zhang, Jianzhang Li, Sheldon Q. Shi, Qiang Gao.  (2022)  Hyperbranched catechol biomineralization for preparing super antibacterial and fire-resistant soybean protein adhesives with long-term adhesion.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2022.137822]

18. Yulin Zheng, Yunlei Zhou, Xiaoting Cui, Huanshun Yin, Shiyun Ai.  (2022)  Enhanced photoactivity of CdS nanorods by MXene and ZnSnO3: Application in photoelectrochemical biosensor for the effect of environmental pollutants on DNA hydroxymethylation in wheat tissues.  Materials Today Chemistry,      [PMID:] [10.1016/j.mtchem.2022.100878]

19. Shufang Liu, Ziqian Liu, Qing Su, Qiaolin Wu.  (2022)  Multifunctional covalent organic frameworks for photocatalytic oxidative hydroxylation of arylboronic acids and fluorescence sensing for Cu2+.  MICROPOROUS AND MESOPOROUS MATERIALS,      [PMID:] [10.1016/j.micromeso.2022.111737]

20. Man-Sha Wu, Ze-Rui Zhou, Xiao-Yuan Wang, Bin-Bin Chen, Mahmoud Elsayed Hafez, Ji-Fen Shi, Da-Wei Li, Ruo-Can Qian.  (2022)  Dynamic Visualization of Endoplasmic Reticulum Stress in Living Cells via a Two-Stage Cascade Recognition Process.  ANALYTICAL CHEMISTRY,      [PMID:35112843] [10.1021/acs.analchem.1c04764]

21. Guohao Li, Nanhang Zhu, Jia Cheng, Yujia Zhang, Yue Yu, Xiaolin Zhang, Qiangying Yi, Yao Wu.  (2021)  Dynamic biological interfaces functionalized fructose-responsive immunomagnetic beads for high-efficient and high-purity exosome enrichment.  MATERIALS & DESIGN,      [PMID:] [10.1016/j.matdes.2021.110366]

22. Baoyue Zhang, Yukui Tong, Jianghua He, Baodong Sun, Feng Zhang, Miaomiao Tian.  (2021)  Boronate-modified polyethyleneimine dendrimer as a solid-phase extraction adsorbent for the analysis of luteolin via HPLC.  RSC Advances,  11  (63): (39821-39828).  [PMID:35494127] [10.1039/D1RA07564K]

23. Yu Zhang, Haifeng Lu, Bing Yan.  (2021)  Determination of urinary N-acetylneuraminic acid for early diagnosis of lung cancer by a boric acid covalently functionalized lanthanide MOFs and its intelligent visual molecular robot application.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2021.130736]

24. Yi Sun, Qingxiang Zhou, Xueying Sheng, Shuanying Li, Yayan Tong, Jinghan Guo, Boyao Zhou, Jingyi Zhao, Menghua Liu, Zhi Li, Yanhui Li, Tongxu Qu, Chunmao Chen.  (2021)  Highly selective fluorescence sensor sensing benzo[a]pyrene in water utilizing carbon dots derived from 4-carboxyphenylboronic acid.  CHEMOSPHERE,      [PMID:34119727] [10.1016/j.chemosphere.2021.131127]

25. Yukui Tong, Baoyue Zhang, Bailin Guo, Wenjie Wu, Yingxue Jin, Fang Geng, Miaomiao Tian.  (2020)  Gallic acid-affinity molecularly imprinted polymer adsorbent for capture of cis-diol containing Luteolin prior to determination by high performance liquid chromatography.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:33383244] [10.1016/j.chroma.2020.461829]

26. Yuhao Weng, Qiaoyu Zhu, Zhen-Zhong Huang, Hongliang Tan.  (2020)  Time-Resolved Fluorescence Detection of Superoxide Anions Based on an Enzyme-Integrated Lanthanide Coordination Polymer Composite.  ACS Applied Materials & Interfaces,      [PMID:32525648] [10.1021/acsami.0c09080]

27. Yu Wenjie, Li Hengye, Zhang Lin, Liu Jing, Kong Fenying, Wang Wei.  (2020)  Preparation of Magnetic Porous Aromatic Framework for Rapid and Efficient Removal of Organic Pollutants from Water.  ANALYTICAL SCIENCES,  36  (10): (1157-1161).  [PMID:32281577] [10.2116/analsci.20P013]

28. Dan Zheng, Jingyang Zhao, Yinghua Tao, Jing Liu, Luying Wang, Jing He, Jiandu Lei, Kefeng Liu.  (2020)  pH and glutathione dual responsive nanoparticles based on Ganoderma lucidum polysaccharide for potential programmable release of three drugs.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2020.124418]

29. Peng Zhang, Qinan Xu, Xinfang Li, Youxiang Wang.  (2019)  pH-responsive polydopamine nanoparticles for photothermally promoted gene delivery.  Materials Science & Engineering C-Materials for Biological Applications,      [PMID:31924025] [10.1016/j.msec.2019.110396]

30. Hou Xingyu, Huang Wei, Tong Yukui, Tian Miaomiao.  (2019)  Hollow dummy template imprinted boronate-modified polymers for extraction of norepinephrine, epinephrine and dopamine prior to quantitation by HPLC.  MICROCHIMICA ACTA,  186  (11): (1-9).  [PMID:31595360] [10.1007/s00604-019-3801-2]

31. Zhanwei Zhou, Yadong Liu, Minghua Zhang, Chenzi Li, Ruoxi Yang, Jing Li, Chenggen Qian, Minjie Sun.  (2019)  Size Switchable Nanoclusters Fueled by Extracellular ATP for Promoting Deep Penetration and MRI-Guided Tumor Photothermal Therapy.  ADVANCED FUNCTIONAL MATERIALS,  29  (39): (1904144).  [PMID:] [10.1002/adfm.201904144]

32. Xiu Ye, Haoying Wang, Lisha Yu, Jinping Zhou.  (2019)  Aggregation-Induced Emission (AIE)-Labeled Cellulose Nanocrystals for the Detection of Nitrophenolic Explosives in Aqueous Solutions.  Nanomaterials,  9  (5): (707).  [PMID:31067707] [10.3390/nano9050707]

33. Wei Zhang, Shuming Li, Jing Zhang, Zhiqi Zhang, Fuquan Dang.  (2019)  Synthesis and adsorption behavior study of magnetic fibrous mesoporous silica.  MICROPOROUS AND MESOPOROUS MATERIALS,      [PMID:] [10.1016/j.micromeso.2019.03.022]

34. Yujie Zhang, Mingxin Wu, Wubin Dai, Yinping Li, Xin Wang, Di Tan, Zhilu Yang, Sheng Liu, Longjian Xue, Yifeng Lei.  (2019)  Gold nanoclusters for controlled insulin release and glucose regulation in diabetes.  Nanoscale,  11  (13): (6471-6479).  [PMID:30892368] [10.1039/C9NR00668K]

35. Yunfan Qiao, Rushi Zhao, Min Zhang, Hongyang Zhang, Yuerong Wang, Ping Hu.  (2019)  Phenylboronic acid derivative-modified (6,5) single-wall carbon nanotube probes for detecting glucose and hydrogen peroxide.  RSC Advances,  9  (4): (2258-2267).  [PMID:35516097] [10.1039/C8RA09272A]

36. Na Xiao, Shi Gang Liu, Shi Mo, Na Li, Yan Jun Ju, Yu Ling, Nian Bing Li, Hong Qun Luo.  (2018)  Highly selective detection of p-nitrophenol using fluorescence assay based on boron, nitrogen co-doped carbon dots.  TALANTA,      [PMID:29674031] [10.1016/j.talanta.2018.02.114]

37. Huixia Di, Huiqiao Liu, Mingmin Li, Jin Li, Dingbin Liu.  (2017)  High-Precision Profiling of Sialic Acid Expression in Cancer Cells and Tissues Using Background-Free Surface-Enhanced Raman Scattering Tags.  ANALYTICAL CHEMISTRY,      [PMID:28462995] [10.1021/acs.analchem.7b00199]

38. Qianghua Ye, Fanyong Yan, Depeng Kong, Jin Zhang, Xuguang Zhou, Jinxia Xu, Li Chen.  (2017)  Constructing a fluorescent probe for specific detection of catechol based on 4-carboxyphenylboronic acid-functionalized carbon dots.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2017.03.081]

39. Hongliang Tan, Chanjiao Ma, Qian Li, Li Wang, Fugang Xu, Shouhui Chen, Yonghai Song.  (2014)  Functionalized lanthanide coordination polymer nanoparticles for selective sensing of hydrogen peroxide in biological fluids.  ANALYST,  139  (21): (5516-5522).  [PMID:25195570] [10.1039/C4AN01152J]

40. Fang Zhu, Lanfang Ren, Wenhua Cheng, Haohan Zhou, Yuhan Li, Nan Liu, Guangyu Rong, Yunfeng Liu, Panting Yu, Jia Lv, Yiyun Cheng, Chao Chen.  (2025)  A Dynamic Deferoxamine Polymer with Exceptional Performance in Mitochondrial Iron Depletion and Cytosolic Protein Delivery.  Small,      [PMID:39945100] [10.1002/smll.202412093]

41. Bowen Deng, Rui Huang, Rui Liang, Yang Fei, Qing Luo, Guanbin Song.  (2024)  Design and evaluation of collagenase-loaded nanoparticles for mechanical intervention of orthotopic hepatocellular carcinoma in rat model.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39638179] [10.1016/j.ijbiomac.2024.138311]

42. Wenshuo Zhang, Tao Zhang, Yuye Zhong, Yinhui Zhang, Laiguo Wang, Feng Zhu, Xie Wang, Le Zhou, Xuehua Zhou.  (2024)  Dynamic borate ester bond reinforced hydroxyethyl cellulose/corn starch crosslinked film for simple recycling and regeneration.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39218188] [10.1016/j.ijbiomac.2024.135231]

43. Yurong Leng, Yanmei Wu, Wenjing Xiao, Xiaoquan Su, Zhe Liu.  (2024)  Dynamic-Covalent Mesoporous Silica Nanohybrid with pH/ROS-Responsive Drug Release for Targeted Tumor Therapy.  ACS Omega,      [PMID:39651082] [10.1021/acsomega.4c04502]

44. Minghui Sun, Muthu Murugananthan, Zhiming Zhou, Yan Shen, Yanrong Zhang, Xiaoguang Wang.  (2024)  Hydrophobic covalent organic frameworks utilized Fluorocarbon/Water system for efficient hydrogen peroxide photosynthesis.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.150245]

45. Qian Wang, Mingzhe Cai, Yafei Ma, Yanhao Zhang, Sheng Chen, Shusheng Zhang.  (2024)  Phenylboronic Acid-Functionalized Ratiometric Surface-Enhanced Raman Scattering Nanoprobe for Selective Tracking of Hg2+ and CH3Hg+ in Aqueous Media and Living Cells.  ANALYTICAL CHEMISTRY,      [PMID:39105712] [10.1021/acs.analchem.4c02238]

46. Guoqing Wang, Jianfei Wang, Xinping Wang, Yuanyuan Meng, Xiangzhen Feng, Gaoli Liu, Dong-An Wang, Changjiang Fan.  (2024)  Porous Materials with Water-Triggered Instant Transformation to Robust Hydrogel Adhesives for Rapid Hemostasis of High-Pressure Hemorrhages.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202419456]

47. Tiantian Wang, Bingbing Xu, Tong Yu, Yan Yu, Jiayi Fu, Yuhang Wang, Xianwu Gao, Zhebin Xue, Ruoxin Li, Guangtao Chang.  (2024)  PVA/chitosan-based multifunctional hydrogels constructed through multi-bonding synergies and their application in flexible sensors.  CARBOHYDRATE POLYMERS,      [PMID:39647941] [10.1016/j.carbpol.2024.123034]

48. Ruirong Wu, Xiufeng Wu, Lan Zhang, Feng Zhang, Yang Ding, Yong Mao, Jiang Ni.  (2025)  Tailored virus-mimicking nanoparticles mediate high transfection of pTRAIL for bystander effects in oncotherapy.  Materials Today Bio,      [PMID:40124336] [10.1016/j.mtbio.2025.101633]

49. Xiaohui Kang, Lanpeng Zhang, Wei Jia, Liang Yang, Changlong Jiang.  (2024)  Visual Detection of Methylglyoxal in Multiple Scenarios via NIR-Excitable Reversible Ratiometric Fluorescent Hydrogel Sensor.  ANALYTICAL CHEMISTRY,      [PMID:39698803] [10.1021/acs.analchem.4c05178]

50. Qiusheng Wang, Jiasheng Yang, Jinmei Meng, Jianyong Yu, Xiaoran Li, Bin Ding.  (2025)  Bioinspired hierarchical fiber-hydrogel dressing with dual immunomodulatory and angiogenic functions for diabetic wound healing.  JOURNAL OF CONTROLLED RELEASE,      [PMID:40712890] [10.1016/j.jconrel.2025.114063]

51. Bohui Zhou, Kangzheng Lv, Ziye Liu, Zhen Li, Daixin Ye, Jinhui Peng, Juan Zhang.  (2025)  Boronic acid modified graphyne nanozyme for the diagnosis of knee joint diseases assisted by machine learning.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.114592]

52. Haihui Xing, Xuan Sun, Lei Xing, Qiaoyun Li, Mingjie Puyang, Lihua Liu, Dan Chen.  (2025)  ROS-responsive ecdysterone nanodelivery system ameliorates Alzheimer's disease via synergistic modulation of oxidative stress and amyloid-β deposition.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.167717]

53. Chenqian Feng, Qiuting Wang, Susu Xiao, Yuanli Yang, Bo Chen, Hui Li, Min Mu, Rangrang Fan, Haifeng Chen, Bo Han, Gang Guo.  (2025)  Adaptive Phenol-Based Hydrogel Embedded with Metformin Nanoparticles Targets Oxidative Stress and Ferroptosis for Spinal Cord Injury Repair.  ACS Nano,      [PMID:40973102] [10.1021/acsnano.5c09794]

54. Yuting Sun, Junnan He, Yongyan Sun, Lidong Wang, Haidu Li, Yaqi Miao, Ping Shi, Jin Zhang, Kaixuan Luo, Yan Zhao.  (2025)  Smart-responsive dual cross-linked chitooligosaccharide nanoparticles with high stability and ROS-triggered self-accelerating drug release for enhanced breast cancer therapy.  CARBOHYDRATE RESEARCH,      [PMID:40967161] [10.1016/j.carres.2025.109671]

55. Bei Wang, Hao Cheng, Zhongsheng Ji, Zijun Jiang, Rong Wang, Yang Ding, Jiang Ni.  (2024)  Synergistic Target-Attacking Tumor Cells and M2 Macrophages via a Triple-Responsive Nanoassembly for Complete Metastasis Blocking.  Advanced Healthcare Materials,      [PMID:39663738] [10.1002/adhm.202304096]

56. Fangling Li, Dongdong Cao, Lixia Yao, Wenyi Gu, Zhiyong Liu, Dongmei Li, Lin Cui.  (2024)  Targeted delivery of miR-34a-5p by phenylborate-coupled polyethylenimide nanocarriers for anti-KSHV treatment.  Frontiers in Bioengineering and Biotechnology,      [PMID:38260739] [10.3389/fbioe.2023.1343956]

57. Wentao Wang, Zhenyu Li, Siming Zhang, Yue Ma, Lei Yu, Qidong Zhang, Guoqing Pan, Dechun Geng, Chen Zhu, Jiaxiang Bai.  (2025)  A Pseudo-Mytilus Edulis Foot Protein-Based Hydrogel Adhesive with Osteo-Vascular-Immune Coupling Effects for Osteoporotic Bone-Implant Integration.  ADVANCED MATERIALS,      [PMID:41190935] [10.1002/adma.202511840]

58. Liu Junyu, Wang Hua, Zhang Caihua.  (2025)  Acteoside-Loaded Self-Healing Hydrogel Enhances Skin Wound Healing through Modulation of Hair Follicle Stem Cells.  Cellular and Molecular Bioengineering,      [PMID:40290106] [10.1007/s12195-025-00845-2]

59. Yuqing Tong, Wei Jiang, Jinyu Li, Peng Teng, Lulu Wei, Huae Xu, Xiqun Jiang, Yong Hu.  (2025)  Biomimetic nanodrug breaching tumor cell membrane barrier for high-efficiency drug delivery.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.163206]

60. Mingzhe Cai, Jiayi Fan, Qian Wang, Yongqian Zhang, Yafei Ma, Jingjie Suo, Miaomiao Zhang, Shusheng Zhang, Sheng Chen.  (2025)  Triple bond-mediated ratiometric surface-enhanced Raman scattering nanoprobe for in vitro and ex vivo quantitative monitoring of mercury.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.163427]

61. Ling-zhijie Kong, Dong Zhou, Guoyan Mo, Mingyue Shu, Wenyan Yu, Hao Cheng, Kaichun Li.  (2025)  Multi-Response Au-Nanohybrid Composite Triggered NIR-Light for Effective Anti-Tumor Therapy in Animal Model.  International Journal of Nanomedicine,      [PMID:40491851] [10.2147/IJN.S519668]

62. Hao Fang, Huihui Chen, Qian Guo, Sicheng Xiong, Mingjian Yao, Xiangmin Li, Xiaolin Huang, Yonghua Xiong.  (2025)  Bifunctional competitive antigen enhanced DLS Immunosensor for the ultrasensitive detection of furosemide in slimming products.  FOOD CHEMISTRY,      [PMID:40602145] [10.1016/j.foodchem.2025.145367]

63. Huixia Di, Zhouhao Lei, Qianyu Li, Peize Xu, Yadi Wang.  (2025)  Accurate and sensitive determination of sialic acid using three-dimensional Raman imaging based on a background-free SERS strategy.  ANALYTICA CHIMICA ACTA,      [PMID:41167897] [10.1016/j.aca.2025.344736]

64. Yunfeng Tang, Xiangtian Deng, Min Yi, Dong Wang, Cheng Zheng, Shichang Zhao, Renliang Zhao.  (2025)  An Injectable Hydrogel Co-Delivering Propranolol and Imiquimod to Synergistically Enhance Immunogenic Cell Death after Melanoma Resection.  Advanced Healthcare Materials,      [PMID:41126715] [10.1002/adhm.202503019]

65. Zeyue Sun, Xiaojun Li, Xueheng Sun, Liuting Chen, Zihang Wang, Xin Feng, Luying Wang, Wenjie Jin, Xin Sun, Jiaju Lu.  (2025)  In situ forming ROS-scavenging hydrogel with STING inhibitor delivery promotes bone mesenchymal stem cells osteogenic differentiation via regulating macrophage M2 polarization.  JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION,      [PMID:41273704] [10.1080/09205063.2025.2590730]

66. Yuyi Zheng, Xiaojie Chen, Qi Zhang, Ziwei Xu, Yixuan Gan, Jing Zhou, Wenlu Li, Yi Wang, Zhong Chen, Di Wu.  (2026)  Inflammation Cascade-Directed Therapy by Biomimetic Polydopamine Nanosystem for Long-Term Management of Ischemic Stroke.  Theranostics,  16  (1): (77).  [PMID:41328343] [10.7150/thno.118196]

67. Zhaorong Ouyang, Siyu Li, Ao Zhang, Shu Ye, Wanqiu Ye, Guolei Wen, Tao Wei, Biao Cai, Houli Liu.  (2026)  Ganoderma lucidum Polysaccharide-Decorated Extracellular Vesicle Enables Synergistical Antitumor Immunotherapy.  Materials Today Bio,      [PMID:41640603] [10.1016/j.mtbio.2026.102832]

68. Jun Cao, Wen-Tao Yang, Dan Cao, Chang-Yi Wu, Peng-Cheng Zhou, Wei Zhu, Si-Jie Liao, Ji-Ming Hu, Ai-Guo Shen, Jürgen Popp.  (2026)  Feedback-Guided SERS-Photothermal Patch for Maintaining Redox Homeostasis in Diabetic Foot Ulcers.  ANALYTICAL CHEMISTRY,      [PMID:41757491] [10.1021/acs.analchem.5c07616]

69. Xinzhu Sun, Yilong Xi, Yun Chen, Jianping Zhou, Jiang Ni, Yang Ding, Huaqing Zhang.  (2026)  Dysfunctional microglia-targeted nanoscavenger synergistically accelerates Aβ clearance and inhibits inflammatory cascade.  BIOMATERIALS,      [PMID:41931967] [10.1016/j.biomaterials.2026.124163]

70. Hua Wei, Liya Zhang, Ke Wang, Tongkun Guo, Yue Liu, Yaqing Liu, Jingcheng Hao.  (2026)  Thermogel-gated field-effect transistor biosensors based on micellar self-assembly for glucose sensing.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:] [10.1016/j.jcis.2026.140352]

71. Ma Haodi, Zhang Liying, Wang Lulu, Liu Junfeng, Sun Haoyang, Ge Shuai, Liu Baoquan, Quan Chunshan.  (2026)  pH-responsive selenium nanoplatform for targeted drug release and immune remodeling in microbiota-associated colorectal cancer.  JOURNAL OF NANOBIOTECHNOLOGY,      [PMID:41787462] [10.1186/s12951-026-04229-0]

72. Jiayi Chen, Xue Jiang, Aining Zhang, Wenjing Meng, Xiangyu Xin, Jingyi Zhu, Wei Li.  (2026)  Biomimetic Hydrogel Microneedle Patch for Treating Corneal Injury-Associated Bacterial Keratitis.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202532033]