10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 72 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Berberine chloride (NSC 646666, Natural Yellow 18) is a quaternary ammonium salt from the group of isoquinoline alkaloids. Berberine activatescaspase 3andcaspase 8, cleavage ofpoly ADP-ribose polymerase (PARP)and the release ofcytochrome c. Berberine chlo
In vitro
In vivo
Cell Data
cell lines：
Concentrations：
Incubation Time：
Powder Purity:≥99%
| Isomeric SMILES | COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)OC.[Cl-] |
|---|---|
| Molecular Weight | 371.81 |
| Beilstein | 3836585 |
| Reaxy-Rn | 3836585 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3836585&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Solubility | Solubility (25°C) In vitro DMSO: 27 mg/mL (196.87 mM); Water: Insoluble; Ethanol: Insoluble; |
|---|
| 1. Chen De Xing, Long Yun Fei. (2025) Acid red G stabilized blue fluorescent copper nanoclusters for the detection of tetracycline. CHEMICAL PAPERS, [PMID:] [10.1007/s11696-025-04244-9] |
| 2. Cunliang Guo, Lilong Du, Xiaoxun Du, Rui Gao, Xinyi Jiao, Zhenhua Li, Tongxing Zhang, Pingsheng Huang, Chuangnian Zhang, Zujian Feng, Weiwei Wang, Baoshan Xu. (2025) ROS-responsive hydrogel loaded with berberine liposome protects against intervertebral disc degeneration by inhibiting mitochondrial fission and apoptosis. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2025.167108] |
| 3. Wei Ji-chang, Lin Xiao-yu, Zhao Yi-hang, Tan Xin-ru, Wang Zhi-xia, Li Yuan-yuan, Huang Xue-mei, Wang Peng-long. (2025) Thermodynamic-driven supramolecular transition from nanofibers to nanospheres: morphology-dependent antibacterial specificity of herb medicines. Chinese Medicine, 20 (1): (1-21). [PMID:40993776] [10.1186/s13020-025-01185-z] |
| 4. Meixuan Zhang, Qin Zhang, Xuemin Mu, Xiaolin Wang, Shuhui Zhang, Wenyi Zhao, Xiaoming Song, Lulu Pan, Yanyan Li. (2025) Caffeic acid-Fe3+ nanohybrids loaded with berberine/baicalin for NIR-activated antibacterial therapy via ROS generation and photothermal effects. JOURNAL OF INORGANIC BIOCHEMISTRY, [PMID:40976081] [10.1016/j.jinorgbio.2025.113070] |
| 5. Ru Cheng, Aoqi Song, Jingjing Jiang, Xijier Qiaolongbatu, Zhenghua Wu, Feng Qian, Shuyu Shen, Liwen Zhang, Zhiyu Wang, Wenjuan Zhao, Yuefen Lou. (2025) Berberine Alleviates Chronic Restraint Stress-Induced Depression-Like Behavior by Modulating Gut Microbiota and SCFA Production in Mice. BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, [PMID:40891178] [10.1002/bab.70043] |
| 6. Sun Qian, Chen De Xing, Tao Yu Ting, Yang Xing Ping, Long Yun Fei. (2025) Preparation of Platinum Nanoclusters Using Acid Red G as a Stabilizer and Detection of Tetracycline. JOURNAL OF ANALYTICAL CHEMISTRY, 80 (9): (1647-1655). [PMID:] [10.1134/S1061934825700844] |
| 7. Wei Ming Liu, Hui Yun Zhou, Li Jun Ren, Jia Jia Yang, Pei Yan Hao, Jia Nan Tong, Ya Wei Chen, Jun Liang Chen, Hyun Jin Park. (2023) Optimization, Characterization, Molecular Docking, and In Vitro Release of BBH/Lysine-β-cyclodextrin Inclusion Complex. ChemistrySelect, 8 (45): (e202303620). [PMID:] [10.1002/slct.202303620] |
| 8. Gang Liu, Fengli Gao, Xiupei Yang, Jingyi Zhang, Suling Yang, Yuanyuan Li, Lin Liu. (2023) Aggregation-induced emission for the detection of peptide ligases with improving ligation efficiency. ANALYTICA CHIMICA ACTA, [PMID:37996157] [10.1016/j.aca.2023.341994] |
| 9. Junpeng Sun, Xiaobang Liu, Jiaqun Du, Jinyu An, Yingqiao Li, Yu Hu, Shuai Cheng, Ying Xiong, Yanan Yu, He Tian, Xifan Mei, Chao Wu. (2023) Manganese-doped albumin-gelatin composite nanogel loaded with berberine applied to the treatment of gouty arthritis in rats via a SPARC-dependent mechanism. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:37730000] [10.1016/j.ijbiomac.2023.126999] |
| 10. Kexin Zhang, Jiaxin Zhu, Ruyi Wang, Wanfang Zhu, Zhongtao Zhang, Liangping Gong, Feng Feng, Wenyuan Liu, Lingfei Han, Wei Qu. (2023) Mitochondria-anchoring self-assembled nanoparticles for multi-path energy depletion: A “nano bomb” in chemo-co-starvation therapy. INTERNATIONAL JOURNAL OF PHARMACEUTICS, [PMID:37364784] [10.1016/j.ijpharm.2023.123180] |
| 11. Chengde Liu, Wanting Du, Luyao Jiang, Yizheng Li, Cheng Liu, Xigao Jian. (2023) Enhanced antibacterial and adhesive properties of chitosan/gelatin hydrogel containing berberine hydrochloride and prepolymerized gallic acid exhibiting aggregation-induced emission. POLYMER ENGINEERING AND SCIENCE, 63 (8): (2596-2612). [PMID:] [10.1002/pen.26398] |
| 12. Yong Zhu, Hailun Li, Huiran Jin, Jingrui Ma, Zhandong Ye, Bingmin Wu, Ying Zhang, Qingping Xiong, Shijie Ding, Jing Chen, Song Huang. (2023) An efficient and green separation method of total alkaloids by resorcinol-formaldehyde aerogel during extraction of Coptis chinensis. INDUSTRIAL CROPS AND PRODUCTS, [PMID:] [10.1016/j.indcrop.2023.116438] |
| 13. Huang Xuemei, Liu Xiaojing, Lin Xiaoyu, Yuan Zhihua, Zhang Yaozhi, Wang Zhijia, Pi Wenmin, Zhao Haoqiang, Lei Haimin, Wang Penglong. (2022) Thermodynamics driving phytochemical self-assembly morphological change and efficacy enhancement originated from single and co-decoction of traditional chinese medicine. JOURNAL OF NANOBIOTECHNOLOGY, 20 (1): (1-15). [PMID:36510210] [10.1186/s12951-022-01734-w] |
| 14. Jingliang Wu, Cuiping Qi, Hao Wang, Qing Wang, Jingui Sun, Jinping Dong, Guohua Yu, Zhiqin Gao, Bo Zhang, Guixiang Tian. (2022) Curcumin and berberine co-loaded liposomes for anti-hepatocellular carcinoma therapy by blocking the cross-talk between hepatic stellate cells and tumor cells. Frontiers in Pharmacology, [PMID:36188590] [10.3389/fphar.2022.961788] |
| 15. Tingting Zhao, Qin Zhang, Feng Cang, Shilong Wu, Yu Jiang, Qiyao Zhao, Yifan Zhou, Xiaomeng Qu, Xuesong Zhang, Yushen Jin, Yanyan Li, Yujie Fu. (2022) Yolk-shell shaped Au-Bi2S3 heterostructure nanoparticles for controlled drug release and combined tumor therapy. NANOTECHNOLOGY, 33 (45): (455103). [PMID:35914421] [10.1088/1361-6528/ac85c2] |
| 16. Xiaoxiao Fan, Qiming Xia, Shunjie Liu, Zheng Zheng, Yiyin Zhang, Tianxiang Wu, Yixuan Li, Guping Tang, Ben Zhong Tang, Jun Qian, Hui Lin. (2022) NIR-II and visible fluorescence hybrid imaging-guided surgery via aggregation-induced emission fluorophores cocktails. Materials Today Bio, [PMID:36052153] [10.1016/j.mtbio.2022.100399] |
| 17. Xingxing Feng, Qi Xie, Hongbo Xu, Tiantian Zhang, Xiaonan Li, Yinmei Tian, Hongbing Lan, Li Kong, Zhiping Zhang. (2022) Yeast Microcapsule Mediated Natural Products Delivery for Treating Ulcerative Colitis through Anti-Inflammatory and Regulation of Macrophage Polarization. ACS Applied Materials & Interfaces, [PMID:35770618] [10.1021/acsami.2c05642] |
| 18. Li Mo, She Jiang, Ma Louyan, Ma Li, Ma Xiaorui, Zhai Jiajia. (2022) Berberine protects against palmitate induced beta cell injury via promoting mitophagy. Genes & Genomics, 44 (7): (867-878). [PMID:35633490] [10.1007/s13258-022-01250-z] |
| 19. Longfa Kou, Huirong Huang, Yingying Tang, Meng Sun, Yingtao Li, Jianing Wu, Shimin Zheng, Xinyu Zhao, Daosen Chen, Zucheng Luo, Xiaolei Zhang, Qing Yao, Ruijie Chen. (2022) Opsonized nanoparticles target and regulate macrophage polarization for osteoarthritis therapy: A trapping strategy. JOURNAL OF CONTROLLED RELEASE, [PMID:35489544] [10.1016/j.jconrel.2022.04.037] |
| 20. Haofeng Hu, Fulin Luo, Qian Zhang, Ming Xu, Xin Chen, Zhihao Liu, Haodong Xu, Lei Wang, Fei Ye, Kui Zhang, Bin Chen, Song Zheng, Jia Jin. (2022) Berberine coated biocomposite hemostatic film based alginate as absorbable biomaterial for wound healing. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:35487376] [10.1016/j.ijbiomac.2022.04.132] |
| 21. Yingxin Chen, Xiaotong Huang, Lu Li, Junxian Wu, Yongqi Guo, Yachao Yao, Lihua Zhou. (2022) Paper mill sludge-based carbon quantum dots as a specifically ratiometric fluorescent probe for the sensitive and selective detection of coptisine. LUMINESCENCE, 37 (7): (1078-1086). [PMID:35441456] [10.1002/bio.4260] |
| 22. Jia-Man Liang, Fang Zhang, Yu-Lin Zhu, Xiao-Yan Deng, Xian-Ping Chen, Qiu-Ju Zhou, Ke-Jun Tan. (2022) One-pot hydrothermal synthesis of Si-doped carbon quantum dots with up-conversion fluorescence as fluorescent probes for dual-readout detection of berberine hydrochloride. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:35313173] [10.1016/j.saa.2022.121139] |
| 23. Qin Wang, Kai-Ni Wei, Shu-Zhen Huang, Qing Tang, Zhu Tao, Ying Huang. (2021) “Turn-Off” Supramolecular Fluorescence Array Sensor for Heavy Metal Ion Identification. ACS Omega, [PMID:34841166] [10.1021/acsomega.1c04956] |
| 24. Miaomiao Qi, Xiang Liu, Ying Zhou, Haoyu Wang, Ying Zhao, Jing Ren, Jin Xiang. (2021) Berberine Inhibits MDA-MB-231 Cells as an Agonist of G Protein-Coupled Estrogen Receptor 1. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22 (21): (11466). [PMID:34768896] [10.3390/ijms222111466] |
| 25. Kai Li, Junyong Zhu, Decheng Liu, Yatao Zhang, Bart Van der Bruggen. (2021) Controllable and Rapid Synthesis of Conjugated Microporous Polymer Membranes via Interfacial Polymerization for Ultrafast Molecular Separation. CHEMISTRY OF MATERIALS, [PMID:] [10.1021/acs.chemmater.1c02143] |
| 26. Liu Mingyang, Du Xuejun, Xu Ke, Yan Binwei, Fan Zaibi, Gao Zideng, Ren Xueqin. (2021) A cationic quantum dot-based ratiometric fluorescent probe to visually detect berberine hydrochloride in human blood serums. Journal of Analytical Science and Technology, 12 (1): (1-9). [PMID:] [10.1186/s40543-021-00261-x] |
| 27. Chao Fan, Hao Tang, Licheng Wang, Yijing Li, Xusheng Wang, Shuai Wang, Xiaojing Liang. (2020) The preparation of a core–shell stationary phase by the in situ polymerization of a hydrophilic polymer on the surface of silica and its chromatographic performance. NEW JOURNAL OF CHEMISTRY, 44 (27): (11704-11709). [PMID:] [10.1039/D0NJ01197E] |
| 28. Hanzhi Zhang, Chunli Lou, Jing Li, Jingwu Kang. (2020) A gold foil covered fused silica capillary tip as a sheathless interface for coupling capillary electrophoresis-mass spectrometry. JOURNAL OF CHROMATOGRAPHY A, [PMID:32540065] [10.1016/j.chroma.2020.461215] |
| 29. Lin Xiao, Abishek Jung Poudel, Lixia Huang, Yang Wang, Ahmed M.E. Abdalla, Guang Yang. (2020) Nanocellulose hyperfine network achieves sustained release of berberine hydrochloride solubilized with β-cyclodextrin for potential anti-infection oral administration. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:32147343] [10.1016/j.ijbiomac.2020.03.030] |
| 30. Wen Caiyan, Huang Cuiqin, Yang Mei, Fan Chongzhu, Li Qin, Zhao Jiayi, Gan Danhui, Li An, Zhu Lihong, Lu Daxiang. (2020) The Secretion from Bone Marrow Mesenchymal Stem Cells Pretreated with Berberine Rescues Neurons with Oxidative Damage Through Activation of the Keap1-Nrf2-HO-1 Signaling Pathway. NEUROTOXICITY RESEARCH, 38 (1): (59-73). [PMID:32108297] [10.1007/s12640-020-00178-0] |
| 31. Meng Wang, Jinglan Zhang, Huayan Zhao, Dingming Wan, Zhongxing Jiang. (2020) Berberine combined with cyclosporine A alleviates acute graft-versus-host disease in murine models. INTERNATIONAL IMMUNOPHARMACOLOGY, [PMID:32050154] [10.1016/j.intimp.2020.106205] |
| 32. Zhou Wen-cheng, Tan Peng-fei, Chen Xing-han, Cen Ying, You Chao, Tan Lin, Li Hao, Tian Meng. (2020) Berberine-Incorporated Shape Memory Fiber Applied as a Novel Surgical Suture. Frontiers in Pharmacology, [PMID:31998123] [10.3389/fphar.2019.01506] |
| 33. Jian Liu, Zhenjing Zhu, Yueyao Liu, Linlin Wei, Bai Li, Fengxia Mao, Ju Zhang, Yingchao Wang, Yufeng Liu. (2019) MDM2 inhibition-mediated autophagy contributes to the pro-apoptotic effect of berberine in p53-null leukemic cells. LIFE SCIENCES, [PMID:31881227] [10.1016/j.lfs.2019.117228] |
| 34. Xuemei Huang, Penglong Wang, Tong Li, Xuehao Tian, Wenbo Guo, Bing Xu, Guangrui Huang, Desheng Cai, Fei Zhou, Hao Zhang, Haimin Lei. (2019) Self-Assemblies Based on Traditional Medicine Berberine and Cinnamic Acid for Adhesion-Induced Inhibition Multidrug-Resistant Staphylococcus aureus. ACS Applied Materials & Interfaces, [PMID:31829617] [10.1021/acsami.9b17722] |
| 35. Hui Wang, Wenbao Wang, Bowen Gong, Zedan Wang, Yukun Feng, Weige Zhang, Shaojie Wang, Ying Peng, Jiang Zheng. (2019) Glutathione Conjugation and Protein Adduction Derived from Oxidative Debromination of Benzbromarone in Mice. DRUG METABOLISM AND DISPOSITION, 47 (11): (1281-1290). [PMID:31484654] [10.1124/dmd.119.087460] |
| 36. Li Li, Qiuhong Li, Lei Wei, Zhongfu Wang, Wei Ma, Fangying Liu, Yanhua Shen, Shanfang Zhang, Xiulian Zhang, Huiping Li, Yechang Qian. (2019) Dexamethasone combined with berberine is an effective therapy for bleomycin‑induced pulmonary fibrosis in rats. Experimental and Therapeutic Medicine, 18 (4): (2385-2392). [PMID:31555349] [10.3892/etm.2019.7861] |
| 37. Xiong Jie, Yang Lu, Gao Li Xia, Zhu Pan Pan, Chen Qian, Tan Ke Jun. (2019) A highly fluorescent lanthanide metal-organic framework as dual-mode visual sensor for berberine hydrochloride and tetracycline. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 411 (23): (5963-5973). [PMID:31300859] [10.1007/s00216-019-02004-9] |
| 38. Yizhen Zhang, Lifen Liu, Qiyuan Chen, Yun He, Michael K.H. Leung. (2019) Electricity generating & high efficiency advanced oxidation process including peroxymonosulfate activation in photocatalytic fuel cell. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2019.122148] |
| 39. Yizhen Zhang, Lifen Liu, Bart Van der Bruggen, Michael K.H. Leung, Fenglin Yang. (2019) A free-standing 3D nano-composite photo-electrode—Ag/ZnO nanorods arrays on Ni foam effectively degrade berberine. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2019.05.026] |
| 40. Jingfu Jia, Kerong Zhang, Xue Zhou, Jinfang Ma, Xiaojing Liu, Anya Xiang, Fahuan Ge. (2019) Berberine-loaded solid proliposomes prepared using solution enhanced dispersion by supercritical CO2: Sustained release and bioavailability enhancement. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, [PMID:] [10.1016/j.jddst.2019.03.021] |
| 41. Hong-Xin Cui, Ya-Nan Hu, Jing-Wan Li, Ke Yuan, Ying Guo. (2018) Preparation and Evaluation of Antidiabetic Agents of Berberine Organic Acid Salts for Enhancing the Bioavailability. MOLECULES, 24 (1): (103). [PMID:30597911] [10.3390/molecules24010103] |
| 42. Jingfu Jia, Kerong Zhang, Xue Zhou, Dan Zhou, Fahuan Ge. (2018) Precise Dissolution Control and Bioavailability Evaluation for Insoluble Drug Berberine via a Polymeric Particle Prepared Using Supercritical CO2. Polymers, 10 (11): (1198). [PMID:30961123] [10.3390/polym10111198] |
| 43. Han Xie, Shao Kaiyuan, Hu Wenxiang. (2018) Synthesis of 9-Substituted Berberine Derivatives with Microwave Irradiation. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 34 (4): (571-577). [PMID:] [10.1007/s40242-018-7425-6] |
| 44. Shiwei Wang, Yi Hou, Shurong Zhang, Jing Li, Qian Chen, Mingan Yu, Wei Li. (2018) Sustained antibacterial activity of berberine hydrochloride loaded supramolecular organoclay networks with hydrogen-bonding junctions. Journal of Materials Chemistry B, 6 (30): (4972-4984). [PMID:32255069] [10.1039/C8TB01018H] |
| 45. Rong Liu, Yonggang Zhang. (2018) Mechanism of UV-driven Photoelectrocatalytic Degradation of Berberine Chloride Form Using the ESR Spin-trapping Method. PHOTOCHEMISTRY AND PHOTOBIOLOGY, 94 (4): (650-658). [PMID:29437228] [10.1111/php.12907] |
| 46. Juntao Yin, Yantao Hou, Yuyun Yin, Xiaoyong Song. (2017) Selenium-coated nanostructured lipid carriers used for oral delivery of berberine to accomplish a synergic hypoglycemic effect. International Journal of Nanomedicine, [PMID:29263662] [10.2147/IJN.S144615] |
| 47. Hui Wang, Ying Peng, Tingjian Zhang, Qunsheng Lan, Huimin Zhao, Wenbao Wang, Yufei Zhao, Xu Wang, Jianxin Pang, Shaojie Wang, Jiang Zheng. (2017) Metabolic Epoxidation Is a Critical Step for the Development of Benzbromarone-Induced Hepatotoxicity. DRUG METABOLISM AND DISPOSITION, 45 (12): (1354-1363). [PMID:29021351] [10.1124/dmd.117.077818] |
| 48. Lingli He, Chuan Li, Xuyuan Liu, Qingqing Yang, Haizhi Zhang, Weiren Xu, Luyong Zhang, Changxiao Liu. (2017) Comparative study on the interaction between 3 CYP2C9 allelic isoforms and benzbromarone by using LC–MS/MS method. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, [PMID:29100760] [10.1016/j.jchromb.2017.10.051] |
| 49. Jing-wan Li, Ke Yuan, Sui-cun Shang, Ying Guo. (2017) A safer hypoglycemic agent for type 2 diabetes—Berberine organic acid salt. Journal of Functional Foods, [PMID:] [10.1016/j.jff.2017.09.031] |
| 50. Ting Tan, Mingliang Zhang, Yiqun Wan, Hongdeng Qiu. (2015) Utilization of deep eutectic solvents as novel mobile phase additives for improving the separation of bioactive quaternary alkaloids. TALANTA, [PMID:26717817] [10.1016/j.talanta.2015.11.041] |
| 51. Guiju Xu, Shengju Liu, Jiaxi Peng, Wenping Lv, Ren’an Wu. (2015) Facile Synthesis of Gold@Graphitized Mesoporous Silica Nanocomposite and Its Surface-Assisted Laser Desorption/Ionization for Time-of-Flight Mass Spectroscopy. ACS Applied Materials & Interfaces, [PMID:25552293] [10.1021/am507894y] |
| 52. Siyuan Sun, Kai Wang, Hongmei Lei, Liping Li, Meijuan Tu, Su Zeng, Hui Zhou, Huidi Jiang. (2013) Inhibition of organic cation transporter 2 and 3 may be involved in the mechanism of the antidepressant-like action of berberine. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, [PMID:24246570] [10.1016/j.pnpbp.2013.11.005] |
| 53. Sui Xiao, Li-Fang Zhang, Xu Zhang, Su-Mei Li, Fei-Qun Xue. (2013) Tracing antibacterial compounds from Acalypha australis Linn. by spectrum-effect relationships and semi-preparative HPLC. JOURNAL OF SEPARATION SCIENCE, [PMID:23495243] [10.1002/jssc.201201202] |
| 54. Wenpeng Zhang, Zilin Chen. (2012) Preparation of micropipette tip-based molecularly imprinted monolith for selective micro-solid phase extraction of berberine in plasma and urine samples. TALANTA, [PMID:23200364] [10.1016/j.talanta.2012.10.014] |
| 55. Zekun Zeng, Zhiwei Yang, Chenghao Li, Shujing Liu, Wei Wei, Ye Zhou, Simeng Wang, Mengjun Sui, Mengdan Li, Shumei Lin, Yangyang Cheng, Peng Hou. (2024) Advancing Cancer Immunotherapy through Engineering New PD-L1 Degraders: A Comprehensive Study from Small Molecules to PD-L1-Specific Peptide–Drug Conjugates. JOURNAL OF MEDICINAL CHEMISTRY, [PMID:39420825] [10.1021/acs.jmedchem.4c01652] |
| 56. Siying Xia, Rui Jing, Mingyan Shi, Yanan Yang, Meiting Feng, Li Deng, Lijun Luo. (2024) BBR affects macrophage polarization via inhibition of NF-κB pathway to protect against T2DM-associated periodontitis. JOURNAL OF PERIODONTAL RESEARCH, [PMID:38501225] [10.1111/jre.13246] |
| 57. Zijun Zhou, Qiusheng Zhao, Yuting Huang, Shan Meng, Xin Chen, Guoxin Zhang, Yanbang Chi, Dengyue Xu, Zongtao Yin, Hui Jiang, Liming Yu, Huishan Wang. (2024) Berberine ameliorates chronic intermittent hypoxia-induced cardiac remodelling by preserving mitochondrial function, role of SIRT6 signalling. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 28 (12): (e18407). [PMID:38894630] [10.1111/jcmm.18407] |
| 58. Wang Yun, Li Zhongrui, Li Renshi, Han Chao, Wang Lei. (2024) Berberine-based self-assembly agents with enhanced synergistic antitumor efficacy. Frontiers in Pharmacology, [PMID:38545553] [10.3389/fphar.2024.1333087] |
| 59. Kaigang An, Xin Li, Jia Chen, Shuang Zhang, Jing Xiao, Qing Wang, Hongdeng Qiu. (2024) Deep eutectic solvent-assisted synthesis of La–Ce hybrid nanorods for the colorimetric determination of tetracycline in foods. Analytical Methods, 16 (22): (3551-3561). [PMID:38780040] [10.1039/D4AY00412D] |
| 60. Yisa Zhou, Ya Zhang, Jian Xue, Rui Wang, Jiale Dong, Zongjie Yin, Chen Guo, Haihui Wang. (2024) Electrochemically assisted preparation of graphitic carbon nitride nanosheet membranes for efficient water purification. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2024.151638] |
| 61. Shaozhi Liu, Guangyao Zhai, Honggang Zhang, Shenghe Si, Yuanyuan Liu, Yuyin Mao, Zeyan Wang, Hefeng Cheng, Peng Wang, Zhaoke Zheng, Ying Dai, Baibiao Huang. (2024) Enhanced Photocatalytic Ozonation Using Modified TiO2 With Designed Nucleophilic and Electrophilic Sites. CHEMISTRY-A EUROPEAN JOURNAL, [PMID:38987889] [10.1002/chem.202401380] |
| 62. Dong Ju Zhou, Wei Ming Liu, Su Ping Dai, Shuai Qiang Jiang, Yin Wang, Jia Jia Yang, Ya Wei Chen, Jun Liang Chen, Hyun Jin Park, Hui Yun Zhou. (2024) Inclusion complex of berberine hydrochloride with serine-β-cyclodextrin: construction, characterization, inclusion mechanisms, and bioactivity. NEW JOURNAL OF CHEMISTRY, 48 (36): (15884-15893). [PMID:] [10.1039/D4NJ02116A] |
| 63. Chen De Xing, Long Yun Fei. (2024) Multifunctional Copper Nanoclusters for the Detection of pH and Berberine Hydrochloride. JOURNAL OF FLUORESCENCE, [PMID:39576459] [10.1007/s10895-024-04033-9] |
| 64. Jing Zhu, Qing Hong Zhang, Wen Wu Wang. (2024) Pattern Recognition of Alkaloids by Inhibiting the Catalytic Activity of Dopzymes for Dopamine. ANALYTICAL CHEMISTRY, [PMID:39014901] [10.1021/acs.analchem.4c01920] |
| 65. Yan Yan, Yuan Haisheng, Yang Fan, Na Heiya, Yu Xiuling, Liu Jingran, Wang Yuzhen. (2024) Seabuckthorn polysaccharides mitigate hepatic steatosis by modulating the Nrf-2/HO-1 pathway and gut microbiota. AMB Express, 14 (1): (1-16). [PMID:39251509] [10.1186/s13568-024-01756-7] |
| 66. Ming Huiyun, Lu Tingting, Zhou Han, Song Wencheng, Dai Haiming. (2024) Synergistic inhibitory effect of atmospheric pressure plasma and berberine on non‑small cell lung cancer cells via inducing apoptosis. MOLECULAR BIOLOGY REPORTS, 52 (1): (1-13). [PMID:39643828] [10.1007/s11033-024-10132-4] |
| 67. Zihan Hou, Chenning Zhang, Jiale Mao, Yunxiao Xia, Huijing Chao, Yuan Sun, Xu Zhao. (2025) Thermal-activated Polydopamine bilayer film exhibits dual-mode synergistic antibacterial properties for enhanced salmon preservation. INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, [PMID:40413834] [10.1016/j.ijfoodmicro.2025.111279] |
| 68. Zihan Hou, Yunxiao Xia, Yuan Sun, Ming Yang, Lingling Wang, Weizhuo Xu, Xu Zhao. (2025) Sodium alginate-based photothermal film: Preparation, antibacterial activity, and application for preservation of Kyoho Grapes. Journal of Future Foods, [PMID:] [10.1016/j.jfutfo.2024.10.004] |
| 69. Zijun Zhou, Yinli Xu, Xiong Xiao, Tao Huang, Jikai Zhao, Yuting Huang, Guoxin Zhang, Bo Xing, Qiusheng Zhao, Zijun Cao, Zhishang Wang, Zongtao Yin, Liming Yu, Huishan Wang. (2025) Berberine inhibits NLRP3 inflammasome activation by upregulating the SIRT6-AMPK pathway to prevent angiotensin II-induced fibrosis and vulnerability to atrial fibrillation. INTERNATIONAL IMMUNOPHARMACOLOGY, [PMID:41273838] [10.1016/j.intimp.2025.115919] |
| 70. Zijun Cao, Jinfeng Duan, Shan Meng, Zijun Zhou, Yuting Huang, Xin Chen, Jikai Zhao, Tao Huang, Guoxin Zhang, Tong Su, Liming Yu, Zongtao Yin, Huishan Wang. (2026) Berberine Reduces Atrial Lipotoxicity and Endoplasmic Reticulum Stress to Alleviate Heart Failure With Preserved Ejection Fraction (HFpEF)-Associated Atrial Fibrillation via AMPK Signaling. PHYTOTHERAPY RESEARCH, [PMID:41556855] [10.1002/ptr.70193] |
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