Bisphenol A glycerolate dimethacrylate（BisGMA） - Reagent grade , CAS No.1565-94-2

CAS: 1565-94-2 Cat. No.: B106764 Molecular Weight: 512.59 EC Number: 216-367-7

GRADE & PURITY Reagent Grade

Synonyms

2,2-bis(4-(2-hydroxy-3-methacryloxypropoxy)phenyl)propane | BISPHENOL A-GLYCIDYL METHACRYLATE | Bis-gma | Bisphenol A glycerolate dimethacrylate | Bisphenol A Glycidyl Methacrylate | Bisphenol A glycidylmethacrylate | Silux | [2-hydroxy-3-[4-[2-[4-[2-hydr

Storage

Store at 2-8°C,Protected from light

Shipped In

Wet ice

Overview

Bisphenol A glycerolate dimethacrylate(BisGMA) is an advanced derivative of Bisphenol A(BPA). It is a conventional epoxy methacrylate that is widely used as a monomer in many applications due to the following properties:
Phenyl ring provides chemical resistance
Ether linkage allows flexibility
Hydroxyl group gives good adhesion
Methacrylate is the reactive site for crosslinking

Application：

The Progress in Development of Dental Restorative Materials
Bisphenol A glycerolate dimethacrylate can be used:
As a crosslinking monomer in the preparation of zwitter ionic monolithic columns for liquid chromatography.
In the preparation of an antibacterial dental adhesive.

Specifications

Synonyms

2, 2-bis(4-(2-hydroxy-3-methacryloxypropoxy)phenyl)propane | BISPHENOL A-GLYCIDYL METHACRYLATE | Bis-gma | Bisphenol A glycerolate dimethacrylate | Bisphenol A Glycidyl Methacrylate | Bisphenol A glycidylmethacrylate | Silux | [2-hydroxy-3-[4-[2-[4-[2-hydr

Specifications & Purity

Reagent grade

Storage

Store at 2-8°C, Protected from light

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Reagent Grade

Names and Identifiers

• Pubchem Sid: 488182090
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488182090
• Canonical Smiles: CC(=C)C(=O)OCC(COC1=CC=C(C=C1)C(C)(C)C2=CC=C(C=C2)OCC(COC(=O)C(=C)C)O)O
• IUPAC Name: [2-hydroxy-3-[4-[2-[4-[2-hydroxy-3-(2-methylprop-2-enoyloxy)propoxy]phenyl]propan-2-yl]phenoxy]propyl] 2-methylprop-2-enoate
• InChIKey: AMFGWXWBFGVCKG-UHFFFAOYSA-N
• INCHI: 1S/C29H36O8/c1-19(2)27(32)36-17-23(30)15-34-25-11-7-21(8-12-25)29(5,6)22-9-13-26(14-10-22)35-16-24(31)18-37-28(33)20(3)4/h7-14,23-24,30-31H,1,3,15-18H2,2,4-6H3
• Isomeric SMILES: CC(=C)C(=O)OCC(COC1=CC=C(C=C1)C(C)(C)C2=CC=C(C=C2)OCC(COC(=O)C(=C)C)O)O
• WGK Germany: 1
• RTECS: UD3438000
• Molecular Weight: 512.59
• Reaxy-Rn: 2316426
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2316426&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Benzene and substituted derivatives
      • Subclass Diphenylmethanes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Benzene and substituted derivatives
• Subclass: Diphenylmethanes
• Intermediate Tree Nodes: Not available
• Direct Parent: Diphenylmethanes
• Alternative Parents: Phenylpropanes Phenoxy compounds Phenol ethers Alkyl aryl ethers Dicarboxylic acids and derivatives Enoate esters Secondary alcohols Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Diphenylmethane - Phenylpropane - Phenoxy compound - Phenol ether - Alkyl aryl ether - Dicarboxylic acid or derivatives - Alpha,beta-unsaturated carboxylic ester - Enoate ester - Carboxylic acid ester - Secondary alcohol - Carboxylic acid derivative - Ether - Hydrocarbon derivative - Organic oxide - Alcohol - Carbonyl group - Organooxygen compound - Organic oxygen compound - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups.
• External Descriptors: diarylmethane

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)

Discover Target: TSHR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTH1R Tclin Parathyroid hormone receptor (47172 Activities)

Discover Target: PTH1R

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)

Discover Target: GLP1R

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POLH Tchem DNA polymerase eta (21678 Activities)

Discover Target: POLH

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SNCA Tchem Alpha-synuclein (10960 Activities)

Discover Target: SNCA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

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GMNN Tbio Geminin (128009 Activities)

Discover Target: GMNN

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ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)

Discover Target: ATAD5

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ATXN2 Tbio Ataxin-2 (54410 Activities)

Discover Target: ATXN2

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Associated Targets(non-human)

ampC Beta-lactamase AmpC (62480 Activities)

Discover Target: ampC

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasmodium falciparum (966862 Activities)

Explore this target

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INS1 (2867 Activities)

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Mechanisms of Action

Chemical and Physical Properties

• Sensitivity: Light sensitive；air sensitive；heat sensitive
• Refractive Index: 1.552
• Flash Point(°C): 110°C
• Molecular Weight: 512.600 g/mol
• XLogP3: 5.100
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 16
• Exact Mass: 512.241 Da
• Monoisotopic Mass: 512.241 Da
• Topological Polar Surface Area: 112.000 Ų
• Heavy Atom Count: 37
• Formal Charge: 0
• Complexity: 698.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 2
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

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