DL-Methionine - ≥99% , CAS No.59-51-8

CAS: 59-51-8 Cat. No.: M104886 Formula: C₅H₁₁NO₂S Molecular Weight: 149.21 Beilstein Registry Number: 636185 EC Number: 200-432-1

GRADE & PURITY ≥99%

Synonyms

DL-2-Amino-4-(methylthio)butanoic acid | H-DL-Met-OH | (±)-2-Amino-4-(methylmercapto)butyric acid

Storage

Store at 2-8°C,Protected from light

Shipped In

Wet ice

Overview

DL-Methionine is an essential nonpolar α-amino acid with oxidative stress defense properties.
An essential nonpolar amino acid with oxidative stress defense properties

Specifications

Synonyms

DL-2-Amino-4-(methylthio)butanoic acid | H-DL-Met-OH | (±)-2-Amino-4-(methylmercapto)butyric acid

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

Methionine can prevent diseases related to hair, skin and nails. It increases the production of lecithin in liver, thus reducing cholesterol level. It is naturally used as a heavy metal chelating agent to regulate ammonia concentration in urine. This can

Storage

Store at 2-8°C,Protected from light

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥99%

Names and Identifiers

Pubchem Sid

504750429

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504750429

Canonical Smiles

CSCCC(C(=O)O)N

IUPAC Name

2-amino-4-methylsulfanylbutanoic acid

InChIKey

FFEARJCKVFRZRR-UHFFFAOYSA-N

INCHI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)

Isomeric SMILES

CSCCC(C(=O)O)N

WGK Germany

1

RTECS

PD0456000

Molecular Weight

149.21

Beilstein

636185

Reaxy-Rn

636185

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=636185&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Methionine and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Methionine and derivatives
• Alternative Parents: Alpha amino acids Thia fatty acids Amino acids Sulfenyl compounds Monocarboxylic acids and derivatives Dialkylthioethers Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Methionine or derivatives - Alpha-amino acid - Thia fatty acid - Fatty acid - Fatty acyl - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Thioether - Sulfenyl compound - Dialkylthioether - Amine - Organic oxygen compound - Primary amine - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Primary aliphatic amine - Carbonyl group - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as methionine and derivatives. These are compounds containing methionine or a derivative thereof resulting from reaction of methionine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
• External Descriptors: sulfur-containing amino acid - alpha-amino acid

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in 5M HCl (100 mg/ml), water (56.6 mg/ml at 25 °C), acetic acid, and warm dilute alcoho. Insoluble in absolute alcohol.
• Sensitivity: Light sensitive.
• Melt Point(°C): 281°C
• Molecular Weight: 149.210 g/mol
• XLogP3: -1.900
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 149.051 Da
• Monoisotopic Mass: 149.051 Da
• Topological Polar Surface Area: 88.600 Ų
• Heavy Atom Count: 9
• Formal Charge: 0
• Complexity: 97.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1