1,2-Dipalmitoyl-L-α-phosphatidyl-D-myo-inositol 4,5-bisphosphate sodium salt - ≥98% , CAS No.1628353-01-4

CAS: 1628353-01-4 Cat. No.: D335803 Molecular Weight: 1036.96

GRADE & PURITY ≥98%

Synonyms

1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) | CMC_6844 | PtdIns(4,5)P | PI[4,5]P2 | CMC_11419 | PIP2[4',5'](16:0/16:0) | hexadecanoic acid, (1R)-1-[[[hydroxy[[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis | D-myo-PI[4,5]P2 |

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Product Describtion:

1,2-Dipalmitoyl-L-α-phosphatidyl-D-myo-inositol 4,5-bisphosphate is a 4,5-bisphosphate group on the inositol ring is critical for binding specifically to PH domains that are commonly present in signalling proteins. Also found in cytoskeleton.

Product Application:

1,2-Dipalmitoyl-L-alpha-phosphatidyl-D-myo-inositol 4,5-bisphosphate is a critical component in signaling pathways

Specifications

Synonyms

1, 2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4, 5-bisphosphate) | CMC_6844 | PtdIns(4, 5)P | PI[4, 5]P2 | CMC_11419 | PIP2[4', 5'](16:0/16:0) | hexadecanoic acid, (1R)-1-[[[hydroxy[[(1R, 2R, 3S, 4R, 5R, 6S)-2, 3, 6-trihydroxy-4, 5-bis | D-myo-PI[4, 5]P2 |

Specifications & Purity

≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Canonical Smiles: CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OC1C(C(C(C(C1O)OP(=O)(O)O)OP(=O)(O)O)O)O)OC(=O)CCCCCCCCCCCCCCC
• IUPAC Name: [(2R)-2-hexadecanoyloxy-3-[hydroxy-[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-diphosphonooxycyclohexyl]oxyphosphoryl]oxypropyl] hexadecanoate
• InChIKey: HKWJHKSHEWVOSS-MRQSADPDSA-N
• INCHI: 1S/C41H81O19P3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(42)55-31-33(57-35(43)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)32-56-63(53,54)60-39-36(44)37(45)40(58-61(47,48)49)41(38(39)46)59-62(50,51)52/h33,36-41,44-46H,3-32H2,1-2H3,(H,53,54)(H2,47,48,49)(H2,50,51,52)/t33-,36-,37+,38+,39-,40-,41-/m1/s1
• Molecular Weight: 1036.96

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Class Glycerophospholipids
      • Subclass Glycerophosphoinositol phosphates
        • Level5 Phosphatidylinositol phosphates
          • Level6 Phosphatidylinositol-4,5-bisphosphates

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Class: Glycerophospholipids
• Subclass: Glycerophosphoinositol phosphates
• Intermediate Tree Nodes: Phosphatidylinositol phosphates
• Direct Parent: Phosphatidylinositol-4,5-bisphosphates
• Alternative Parents: Phosphatidylinositols Inositol phosphates Monoalkyl phosphates Fatty acid esters Dialkyl phosphates Cyclohexanols Dicarboxylic acids and derivatives Carboxylic acid esters Polyols Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic homomonocyclic compounds
• Substituents: Diacylglycerophosphoinositol-4,5-bisphosphate - Diacylglycerophosphoinositol - Glycerophosphoinositol - Inositol phosphate - Cyclohexanol - Fatty acid ester - Dialkyl phosphate - Monoalkyl phosphate - Cyclitol or derivatives - Dicarboxylic acid or derivatives - Organic phosphoric acid derivative - Phosphoric acid ester - Fatty acyl - Alkyl phosphate - Cyclic alcohol - Carboxylic acid ester - Secondary alcohol - Carboxylic acid derivative - Polyol - Alcohol - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Organooxygen compound - Carbonyl group - Aliphatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as phosphatidylinositol-4,5-bisphosphates. These are phosphatidylinositol bisphosphates in which the two phosphate groups are at C-4 and C-5 of the inositol moiety.
• External Descriptors: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in water, DMSO, methanol, ethanol, and chloroform.
• Molecular Weight: 971.000 g/mol
• XLogP3: 8.000
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 19
• Rotatable Bond Count: 42
• Exact Mass: 970.458 Da
• Monoisotopic Mass: 970.458 Da
• Topological Polar Surface Area: 303.000 Ų
• Heavy Atom Count: 63
• Formal Charge: 0
• Complexity: 1350.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 7
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1