Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 14 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes.
| Isomeric SMILES | C1=CC2=C3C(=C1)C=CC4=C(C=CC(=C43)C=C2)O |
|---|---|
| WGK Germany | 3 |
| RTECS | UR2845000 |
| Molecular Weight | 218.25 |
| Reaxy-Rn | 1875750 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1875750&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Melt Point(°C) | 179-182°C |
|---|
| 1. Miao Yang, Kanmin Mao, Xin Cao, Hongjuan Liu, Xinzheng Wang, Weifeng Mao, Liping Hao. (2023) Metabolism and elimination kinetics of mono-hydroxylated PAHs metabolites following single exposure to different combinations of PAH4 in rats. JOURNAL OF APPLIED TOXICOLOGY, [PMID:37189300] [10.1002/jat.4497] |
| 2. Yuan Li, Yutong Li, Chao Du, Pengju Zhang, Peipei Cen, Xinsheng Liu, Yonghong Li. (2021) Electrochemical Sensing of 1-hydroxypyrene on a Colloidal Gold Modified Zeolitic Imidazolate Frameworks-67/Carbon Nanofiber Paste Electrode. JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 168 (5): (057509). [PMID:] [10.1149/1945-7111/abf216] |
| 3. Yuan Li, Yutong Li, Yan Wang, Guodong Ma, Xinsheng Liu, Yonghong Li, Jeffrey Soar. (2020) Application of zeolitic imidazolate frameworks (ZIF-8)/ionic liquid composites modified nano-carbon paste electrode as sensor for electroanalytical sensing of 1-hydroxypyrene. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2020.105433] |
| 4. Luping Sun, Shuyun Zhu, Zhenjia Zheng, Jing Sun, Xian-En Zhao, Huwei Liu. (2020) 9-Plex ultra high performance liquid chromatography tandem mass spectrometry determination of free hydroxyl polycyclic aromatic hydrocarbons in human plasma and urine. JOURNAL OF CHROMATOGRAPHY A, [PMID:32505283] [10.1016/j.chroma.2020.461182] |
| 5. Jiangping Cao, Qilong Xie, Hongwei Di, Yongfeng Liang, Gui Ma, Zonghui Yi, Ping Zhang, Peng Fu, Jikai Li. (2020) Molecular complex based dispersive liquid–liquid microextraction for simultaneous HPLC determination of eight phenolic compounds in water samples. JOURNAL OF MOLECULAR LIQUIDS, [PMID:] [10.1016/j.molliq.2020.113115] |
| 6. Xue Jin-Hua, Liu Ling, Wang Yong-Sheng, Li Jia-Qian, Li Mei, Qu Yue-Ning, Li Le. (2019) Assay of 1-hydroxypyrene via aggregation-induced quenching of the fluorescence of protamine-modified gold nanoclusters and 9-hydroxyphenanthrene-based sensitization. MICROCHIMICA ACTA, 186 (11): (1-9). [PMID:31617023] [10.1007/s00604-019-3810-1] |
| 7. Long Yu, Qutong Zheng, Di Wu, Yuxiu Xiao. (2019) Bimetal-organic framework nanocomposite based point-of-care visual ratiometric fluorescence pH microsensor for strong acidity. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2019.05.037] |
| 8. Langjun Zhou, Yuling Hu, Gongke Li. (2016) Conjugated Microporous Polymers with Built-In Magnetic Nanoparticles for Excellent Enrichment of Trace Hydroxylated Polycyclic Aromatic Hydrocarbons in Human Urine. ANALYTICAL CHEMISTRY, [PMID:27282655] [10.1021/acs.analchem.6b01708] |
| 9. Zhang Ran, Xu Lihua, Chen Hui, Qin Zhihong, Zhao Yu, Ni Zhonghai. (2015) Convenient synthesis of 1-thiohydroxypyrene by Newman-Kwart rearrangement. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 31 (2): (224-227). [PMID:] [10.1007/s40242-015-4356-3] |
| 10. Haidong Gao, Shucai Gao, Ming Lv, Yeru Liu, Jingjing Yao, Hongwei Liu, Fayun Wang, Mantang Chen, Libin Wan. (2024) Determination of hydroxypolycyclic aromatic hydrocarbons in urine by electromembrane extraction coupled with liquid chromatography. JOURNAL OF CHROMATOGRAPHY A, [PMID:39284253] [10.1016/j.chroma.2024.465375] |
| 11. Zhuo Chen, Zhiyang Lu, Weijun Tian, Bingkun Liu, Bingjie Huo, Jing Zhao, Mengyuan Zou, Ruijuan Zhang, Xinran Yu, Xinbo Wang. (2025) Photocatalytic degradation of Pyrene and derivatives by Ag3PO4/BiOBr supported on Ni foam. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2025.131730] |
| 12. Mei Wang, Na Luo, Yanpeng Gao, Guiying Li, Taicheng An. (2024) Pyrene and its derivatives increase lung adverse effects by activating aryl hydrocarbon receptor transcription. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:38220008] [10.1016/j.scitotenv.2024.170030] |
| 13. Jin Chen, Yiwei Fang, Borui Sun, Ying Xu, Wanyi Chen, Kai zhao, Huiping Zhang. (2025) Association between polycyclic aromatic hydrocarbons exposure and gestational hypertension: Insights from global and dose metabolomics analysis. Journal of Environmental Sciences, [PMID:41461512] [10.1016/j.jes.2025.05.030] |
| 14. Yifan Li, Junbo Li, Yang Yang, Chunyi Wei, Yuting Song, Bo Jiang, Yunfei Xie, Wei Ji. (2026) A SERS-Based Analytical Strategy for Real-Time Quantitative Kinetic Analysis and Inhibitor Screening for Cytochrome P450-Mediated PAH Metabolism. ANALYTICAL CHEMISTRY, [PMID:] [10.1021/acs.analchem.6c00025] |
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