≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
It is a quinolone derivative.It has been reported as metabolite of 8-hydroxyquinoline-N-oxide in rabbits. Synthesis of 2,8-quinolinediol has been reported. It is reported as one of the six possible forms of 8-hydroxycarbostyril.It has been detected as new UV-absorbing compound (UAC) in cow milk and its structure was elucidated using HRMS and by 1H, 13C and 1H ×13C NMR.It is also known as 8-hydroxycarbostyril or 8-hydroxyquinolin-2(1H)-one.
It is suitable for use as standard in a study to identify the urinary metabolites for the toxicity related processes and pathogenesis induced by doxorubicin (DOX) to rats by online and off-line LC-MS techniques.It may be used as starting reagent for the preparation of two powerful β2-adrenergic receptor agonists, used for the treatment of asthma: Procaterol and Indacaterol.
| Pubchem Sid | 488187044 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488187044 |
| Canonical Smiles | C1=CC2=C(C(=C1)O)NC(=O)C=C2 |
| IUPAC Name | 8-hydroxy-1H-quinolin-2-one |
| InChIKey | ZXZKYYHTWHJHFT-UHFFFAOYSA-N |
| INCHI | 1S/C9H7NO2/c11-7-3-1-2-6-4-5-8(12)10-9(6)7/h1-5,11H,(H,10,12) |
| Isomeric SMILES | C1=CC2=C(C(=C1)O)NC(=O)C=C2 |
| WGK Germany | 3 |
| Molecular Weight | 161.16 |
| Beilstein | 21173 |
| Reaxy-Rn | 472906 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=472906&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Quinolines and derivatives |
| Subclass | Quinolones and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Quinolones and derivatives |
| Alternative Parents | 8-hydroxyquinolines Hydroxypyridines 1-hydroxy-4-unsubstituted benzenoids 1-hydroxy-2-unsubstituted benzenoids Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Quinolone - 8-hydroxyquinoline - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Hydroxypyridine - Pyridine - Benzenoid - Heteroaromatic compound - Azacycle - Hydrocarbon derivative - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as quinolones and derivatives. These are compounds containing a quinoline moiety which bears a ketone group. |
| External Descriptors | a small molecule |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 E1705027 | Certificate of Analysis | Jun 15, 2026 | H137479 |
| L2208157 | Certificate of Analysis | Jun 09, 2026 | H137479 |
| L2208436 | Certificate of Analysis | Jun 09, 2026 | H137479 |
| L2208437 | Certificate of Analysis | Jun 09, 2026 | H137479 |
| G2417483 | Certificate of Analysis | May 08, 2026 | H137479 |
| G2417484 | Certificate of Analysis | May 08, 2026 | H137479 |
| C2212437 | Certificate of Analysis | Sep 09, 2025 | H137479 |
| C2212443 | Certificate of Analysis | Sep 09, 2025 | H137479 |
| C2214138 | Certificate of Analysis | Sep 09, 2025 | H137479 |
| C2214142 | Certificate of Analysis | Sep 09, 2025 | H137479 |
| L2208152 | Certificate of Analysis | Mar 10, 2025 | H137479 |
| L2208158 | Certificate of Analysis | Mar 10, 2025 | H137479 |
| L2208187 | Certificate of Analysis | Nov 05, 2024 | H137479 |
| C2212445 | Certificate of Analysis | Feb 15, 2022 | H137479 |
| Melt Point(°C) | 290°C(lit.) |
|---|---|
| Molecular Weight | 161.160 g/mol |
| XLogP3 | 1.000 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 0 |
| Exact Mass | 161.048 Da |
| Monoisotopic Mass | 161.048 Da |
| Topological Polar Surface Area | 49.300 Ų |
| Heavy Atom Count | 12 |
| Formal Charge | 0 |
| Complexity | 225.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
