2-Acetylthiazole - ≥99% , CAS No.24295-03-2

CAS: 24295-03-2 Cat. No.: A124071 Molecular Weight: 127.16 Beilstein Registry Number: 109803 EC Number: 246-134-5
AVAILABLE TO ORDER
GRADE & PURITY ≥99%
Synonyms
1-thiazol-2-yl-ethanone | Methyl 2-thiazolyl ketone, 8CI | 1-(1,3-Thiazol-2-yl)ethanone | Ethanone, 1-(2-thiazolyl)- | Ketone, methyl 2-thiazolyl | 1-(1,3-Thiazol-2-yl)ethan-1-one | 1-(Thiazol-2-yl)ethan-1-one
Storage
Argon charged,Room temperature
Shipped In
Normal
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Size
Status
Price
Qty
5g
A124071-5g
4
$9.90
10g
A124071-10g
1
$10.90
25g
A124071-25g
8

$15.90

$23.90
Save $8.00 (33.47%)
100g
A124071-100g
9

$62.90

$94.90
Save $32.00 (33.72%)
500g
A124071-500g
1

$241.90

$362.90
Save $121.00 (33.34%)
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Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Argon charged,Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 17 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

2-Acetylthiazole is useful for preparing triazolothiazoles, chiral alcohols, and in aldol condensation reactions.
Useful for preparation of triazolothiazoles,chiral alcohols,and in aldol condensation reactions.

Specifications

Synonyms
1-thiazol-2-yl-ethanone | Methyl 2-thiazolyl ketone, 8CI | 1-(1, 3-Thiazol-2-yl)ethanone | Ethanone, 1-(2-thiazolyl)- | Ketone, methyl 2-thiazolyl | 1-(1, 3-Thiazol-2-yl)ethan-1-one | 1-(Thiazol-2-yl)ethan-1-one
Specifications & Purity
≥99%
Storage
Argon charged, Room temperature
Shipped In
Normal
Purity
≥99%
Names and Identifiers
Pubchem Sid488190046
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488190046
Canonical SmilesCC(=O)C1=NC=CS1
IUPAC Name1-(1,3-thiazol-2-yl)ethanone
InChIKeyMOMFXATYAINJML-UHFFFAOYSA-N
INCHI1S/C5H5NOS/c1-4(7)5-6-2-3-8-5/h2-3H,1H3
Isomeric SMILES CC(=O)C1=NC=CS1
WGK Germany 3
Molecular Weight 127.16
Beilstein 109803
Reaxy-Rn 109803
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=109803&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic oxygen compounds
ClassOrganooxygen compounds
SubclassCarbonyl compounds
Intermediate Tree Nodes Ketones - Aryl ketones
Direct ParentAryl alkyl ketones
Alternative Parents Thiazoles  Heteroaromatic compounds  Azacyclic compounds  Organopnictogen compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Aryl alkyl ketone - Heteroaromatic compound - Thiazole - Azole - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organonitrogen compound - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as aryl alkyl ketones. These are ketones have the generic structure RC(=O)R', where R = aryl group and R'=alkyl group.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

15 results found

Lot NumberCertificate TypeDateItem
D2220029Certificate of AnalysisFeb 04, 2026 A124071
D2220037Certificate of AnalysisFeb 04, 2026 A124071
H2113173Certificate of AnalysisMay 12, 2025 A124071
H2113174Certificate of AnalysisMay 12, 2025 A124071
F2426070Certificate of AnalysisMay 21, 2024 A124071
F2426129Certificate of AnalysisMay 21, 2024 A124071
F2426148Certificate of AnalysisMay 21, 2024 A124071
D2418196Certificate of AnalysisMar 22, 2024 A124071
D2418197Certificate of AnalysisMar 22, 2024 A124071
D2418198Certificate of AnalysisMar 22, 2024 A124071
D1503013Certificate of AnalysisDec 14, 2022 A124071
C2302608Certificate of AnalysisMar 04, 2022 A124071
D2220040Certificate of AnalysisMar 04, 2022 A124071
E2312101Certificate of AnalysisMar 04, 2022 A124071
E2312149Certificate of AnalysisMar 04, 2022 A124071

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Chemical and Physical Properties
Sensitivityair sensitive & Moisture sensitive
Refractive Index1.548
Flash Point(°F)172.4 °F
Flash Point(°C)78°C(Lit.)
Boil Point(°C)90°C/12mmHg
Molecular Weight127.170 g/mol
XLogP31.000
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass127.009 Da
Monoisotopic Mass127.009 Da
Topological Polar Surface Area58.200 Ų
Heavy Atom Count8
Formal Charge0
Complexity105.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Tong Zhou, Xue Xia, Heping Cui, Khizar Hayat, Xiaoming Zhang, Chi-Tang Ho.  (2023)  Promotion or Inhibition Effects of Exogenous Glutathione-Degraded Amino Acids on the Formation of 2,3-Butanedione and Pyrazines via Varied Pathways of Interaction with α-Dicarbonyl Compounds Derived from N-(1-Deoxy-d-xylulos-1-yl)-alanine.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:37737140] [10.1021/acs.jafc.3c04424]
2. Tong Zhou, Xue Xia, Heping Cui, Yun Zhai, Foxin Zhang, Khizar Hayat, Xiaoming Zhang, Chi-Tang Ho.  (2023)  Cysteine-Induced pH-Dependent Formation of Thiols and Sulfides or 2-Acetylthiazole and Pyrazines during Thermal Treatment of N-(1-Deoxy-d-xylulos-1-yl)-alanine.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:36696632] [10.1021/acs.jafc.2c08360]
3. Yun-Jiao Ma, Tao Zhou, Wei Jiang, Bei-Wei Zhu, Ming Du, Xian-Bing Xu.  (2022)  Balanced extraction of volatile and semi-volatile compounds by dynamic linked position unity solid-phase microextraction.  FOOD CHEMISTRY,      [PMID:36508869] [10.1016/j.foodchem.2022.135160]
4. Tong Zhou, Xue Xia, Heping Cui, Khizar Hayat, Xiaoming Zhang, Chi-Tang Ho.  (2022)  Competitive Formation of 2,3-Butanedione and Pyrazines through Intervention of Added Cysteine during Thermal Processing of Alanine-Xylose Amadori Compounds.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:36444759] [10.1021/acs.jafc.2c07026]
5. Meichen Liu, Jingyang Yu, Tong Zhou, Huaneng Xu, Khizar Hayat, Xiaoming Zhang, Chi-Tang Ho.  (2022)  Formation Priority of Pyrazines and 2-Acetylthiazole Dependent on the Added Cysteine and Fragments of Deoxyosones during the Thermal Process of the Glycine–Ribose Amadori Compound.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:36070497] [10.1021/acs.jafc.2c04874]
6. Dong-Yu Shen, Meng-Ke Li, Mu Zhao, Jie Li, Xinyue Cui, Ting-Ting Zou, Huan-Lu Song, Jian Xiong, Ku Li.  (2022)  Characterization of key odor-active compounds in pure chicken powder and the effect of yeast extract, using instrumental and sensory techniques.  JOURNAL OF FOOD COMPOSITION AND ANALYSIS,      [PMID:] [10.1016/j.jfca.2022.104879]
7. Lin Wang, Cong Li, Sam Al-Dalali, Yiyang Liu, Hui Zhou, Conggui Chen, Baocai Xu, Ying Wang.  (2022)  Characterization of key aroma compounds in traditional beef soup.  JOURNAL OF FOOD COMPOSITION AND ANALYSIS,      [PMID:] [10.1016/j.jfca.2022.104839]
8. Meng Wei, Xiaochang Liu, Peng Xie, Yuanhua Lei, Haojie Yu, Aiyun Han, Libin Xie, Hongliang Jia, Shaohua Lin, Yueyu Bai, Baozhong Sun, Songshan Zhang.  (2022)  Characterization of Volatile Profiles and Correlated Contributing Compounds in Pan-Fried Steaks from Different Chinese Yellow Cattle Breeds through GC-Q-Orbitrap, E-Nose, and Sensory Evaluation.  MOLECULES,  27  (11): (3593).  [PMID:35684525] [10.3390/molecules27113593]
9. Jing Li, Youyou Yang, Chaohua Tang, Shengnan Yue, Qingyu Zhao, Fadi Li, Junmin Zhang.  (2022)  Changes in lipids and aroma compounds in intramuscular fat from Hu sheep.  FOOD CHEMISTRY,      [PMID:35413762] [10.1016/j.foodchem.2022.132611]
10. Junyi Wang, Ruifang Wang, Yan Gao, Jing Wang, Lina Qiao, Huijuan Li, Guohua Zhao, Ning Zhang, Hitao Chen, Jie Sun, Shuqi Wang.  (2025)  Analysis of dynamic flavor changes of volatile and non-volatile fractions analysis of black qingke (Hordeum vulgare L. var. nudum Hook. f.) during steaming process.  JOURNAL OF FOOD SCIENCE,  90  (2): (e17660).  [PMID:39929602] [10.1111/1750-3841.17660]
11. Yimeng Ren, Longzhu Zhou, Chaohua Tang, Jing Li, Yujie Shi, Qingyu Zhao, Junmin Zhang, Yueyu Bai.  (2025)  Characterization of lipid distribution and volatile profile in high-marbling beef of Jiaxian Red cattle.  JOURNAL OF FOOD COMPOSITION AND ANALYSIS,      [PMID:] [10.1016/j.jfca.2025.107374]
12. Longzhu Zhou, Yimeng Ren, Yujie Shi, Shijie Fan, Liyuan Zhao, Miaomiao Dong, Jing Li, Youyou Yang, Yanan Yu, Qingyu Zhao, Junmin Zhang, Chaohua Tang.  (2024)  Comprehensive foodomics analysis reveals key lipids affect aroma generation in beef.  FOOD CHEMISTRY,      [PMID:39186890] [10.1016/j.foodchem.2024.140954]
13. Shen Cong, Yan Jing, Ai Zhipeng, Huang Hongbing, Mo Lin, Liang Bangzhi, Zhang ChangHui.  (2024)  Insights into the newly synthesized bi- Mannich base for carbon steel corrosion inhibition in H2S and HCl solution.  Scientific Reports,  14  (1): (1-14).  [PMID:39191811] [10.1038/s41598-024-70905-6]
14. Meng Wei, Xiaochang Liu, Peng Xie, Aiyun Han, Yuanhua Lei, Xiaodong Yang, Yinchu Liu, Songshan Zhang, Baozhong Sun.  (2024)  Investigating the interactions between selected heterocyclic flavor compounds and beef myofibrillar proteins using SPME-GC–MS, spectroscopic, and molecular docking approaches.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2024.124878]
15. Jing Wang, Ruifang Wang, Junyi Wang, Yan Gao, Lina Qiao, Ning Zhang.  (2025)  Recognition of characteristic aroma-active components in Qingke (highand barley) through flavoromics analysis.  FOOD CHEMISTRY,      [PMID:40602137] [10.1016/j.foodchem.2025.145262]
16. Pingyang Li, Yiyu Yin, Shijie Fan, Longzhu Zhou, Huihui Tian, Lupei Zhang, Jing Li, Kehan Ma, Junwei Hu, Yanan Yu, Qingyu Zhao, Youyou Yang, Yahui Wang, Ruiqi Peng, Yanxiang Zhang, Xuemei Gao, Yuchang Qin, Junmin Zhang, Chaohua Tang.  (2025)  Multi-omics Analysis of Lipids and Aroma Compounds in Beef under Grain-fed and Grass-fed Production Methods.  Current Research in Food Science,      [PMID:41140574] [10.1016/j.crfs.2025.101216]
17. Jing Li, Huihui Tian, Miaomiao Dong, Yimeng Ren, Longzhu Zhou, Yujie Shi, Qingyu Zhao, Chaohua Tang, Junmin Zhang, Yueyu Bai.  (2026)  Elucidating key lipids driving aroma differences and potential formation pathways in marbled beef with interindividual lipid variations.  FOOD CHEMISTRY,      [PMID:41797043] [10.1016/j.foodchem.2026.148641]
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