≥96%(GC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Argon charged,Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 9 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
3-Glycidoxypropyldimethoxymethylsilane (GDMMS) is an epoxy-silane that is used to form a silane based coupling agent for functionalization of a variety of substrates. The epoxy groups allow good adhesion of surface atoms and form a stable polymeric structure.
3-Glycidoxypropyldimethoxymethylsilane (GDMMS) precursor was used to develop zwitterionic push – pull chromophore and carbazole-derivatives-doped hybrid organic–inorganic homogeneous films.
GDMMS can surface modify indium tin oxide (ITO) glass substrate for the immobilization of surface atoms which can be further used for the electrochemical detection and labeling. It can also be used as a hardener in the formation of multi-component silicone based rubber.
| Canonical Smiles | CO[Si](C)(CCCOCC1CO1)OC |
|---|---|
| IUPAC Name | dimethoxy-methyl-[3-(oxiran-2-ylmethoxy)propyl]silane |
| InChIKey | WHGNXNCOTZPEEK-UHFFFAOYSA-N |
| INCHI | 1S/C9H20O4Si/c1-10-14(3,11-2)6-4-5-12-7-9-8-13-9/h9H,4-8H2,1-3H3 |
| Isomeric SMILES | CO[Si](C)(CCCOCC1CO1)OC |
| Molecular Weight | 220.34 |
| Reaxy-Rn | 11544388 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11544388&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organometallic compounds |
| Class | Organometalloid compounds |
| Subclass | Organosilicon compounds |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Alkoxysilanes |
| Alternative Parents | Silyl ethers Oxacyclic compounds Organoheterosilanes Organic metalloid salts Epoxides Dialkyl ethers Hydrocarbon derivatives |
| Molecular Framework | Aliphatic heteromonocyclic compounds |
| Substituents | Alkoxysilane - Silyl ether - Organoheterosilane - Oxacycle - Organic metalloid salt - Organoheterocyclic compound - Ether - Oxirane - Dialkyl ether - Organic oxygen compound - Hydrocarbon derivative - Organic salt - Organooxygen compound - Aliphatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as alkoxysilanes. These are organosilicon compounds with the general formula RO[Si](OR')(R'')(R''') (R,R' = organyl; R'',R''' = any atom). |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 J2217614 | Certificate of Analysis | May 11, 2026 | G134407 |
| E2415377 | Certificate of Analysis | Feb 05, 2026 | G134407 |
| E2415389 | Certificate of Analysis | Feb 05, 2026 | G134407 |
| K2504136 | Certificate of Analysis | Nov 08, 2025 | G134407 |
| I2306487 | Certificate of Analysis | Jun 10, 2025 | G134407 |
| I2306488 | Certificate of Analysis | Jun 10, 2025 | G134407 |
| D2324603 | Certificate of Analysis | Feb 07, 2025 | G134407 |
| J2217628 | Certificate of Analysis | Aug 14, 2024 | G134407 |
| G2123138 | Certificate of Analysis | May 10, 2023 | G134407 |
| G2123139 | Certificate of Analysis | May 10, 2023 | G134407 |
| G2123137 | Certificate of Analysis | May 10, 2023 | G134407 |
| D2324599 | Certificate of Analysis | Apr 17, 2023 | G134407 |
| J2217626 | Certificate of Analysis | Jul 19, 2022 | G134407 |
| Sensitivity | Moisture and Heat sensitive |
|---|---|
| Refractive Index | 1.432 |
| Flash Point(°C) | 132°C(lit.) |
| Boil Point(°C) | 100°C |
| Molecular Weight | 220.340 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 8 |
| Exact Mass | 220.113 Da |
| Monoisotopic Mass | 220.113 Da |
| Topological Polar Surface Area | 40.200 Ų |
| Heavy Atom Count | 14 |
| Formal Charge | 0 |
| Complexity | 161.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Yingdong Wu, Lu Bai, Junping Zheng. (2023) A robust and efficiently reprocessable poly(dimethylsiloxane) elastomers enhanced by self-catalysis Zn(II)-ligand bonds and silyl ethers. JOURNAL OF POLYMER SCIENCE, 62 (5): (870-879). [PMID:] [10.1002/pol.20230431] |
| 2. Xiaojing Cui, Yequn Liu, Wenjun Yan, Yanfeng Xue, Yangang Mei, Jiamei Li, Xiaoqing Gao, He Zhang, Shanhui Zhu, Yulan Niu, Tiansheng Deng. (2023) Enhancing methanol selectivity of commercial Cu/ZnO/Al2O3 catalyst in CO2 hydrogenation by surface silylation. APPLIED CATALYSIS B-ENVIRONMENTAL, [PMID:] [10.1016/j.apcatb.2023.123099] |
| 3. Yihao Yang, Yuanyuan Tu, Xuefeng Gui, Zhijun Liu, Yaodong Zhang, Xiaohua Cui, Zhenzhu Huang, Zehui Dai. (2023) Facile fabrication of wear-resistant, fluorine-free, strongly adhesive superhydrophobic coating based on modified SiO2/silicone nanocomposites. PROGRESS IN ORGANIC COATINGS, [PMID:] [10.1016/j.porgcoat.2023.107694] |
| 4. Qi Wang, Fengna Dai, Shangying Zhang, Mengxia Wang, Chunhai Chen, Youhai Yu. (2021) Design of a novel poly(aryl ether nitrile)-based composite ultrafiltration membrane with improved permeability and antifouling performance using zwitterionic modified nano-silica. RSC Advances, 11 (25): (15231-15244). [PMID:35424037] [10.1039/D1RA00376C] |
| 5. Zhihao Si, Chang Liu, Guozhen Li, Ze Wang, Jingfang Li, Tanlong Xue, Shuai Yang, Di Cai, Shufeng Li, Haoning Zhao, Peiyong Qin, Tianwei Tan. (2020) Epoxide-based PDMS membranes with an ultrashort and controllable membrane-forming process for 1-butanol/water pervaporation. JOURNAL OF MEMBRANE SCIENCE, [PMID:] [10.1016/j.memsci.2020.118472] |
| 6. Jing Zhu, Xinzhen Zhao, Chunju He. (2015) Zwitterionic SiO2 nanoparticles as novel additives to improve the antifouling properties of PVDF membranes. RSC Advances, 5 (66): (53653-53659). [PMID:] [10.1039/C5RA05571G] |
| 7. Lingxiao Yan, Hongyan Wang, Zhe Sun, Lulu Wang, Chenying Li, Song Xue, Qiang Liu. (2024) Enhanced Performance of Lithium-Ion Batteries Based on a Polyethylenimine-Grafted SiO2-Modified Polypropylene Separator. ACS Applied Polymer Materials, [PMID:] [10.1021/acsapm.4c02222] |
| 8. Zhang Qiuxue, Deng Yunjiao, Fu Zhongyu, Wang Shuangquan, Li Songsong, Zhou Chao, Zhang Huixuan. (2024) Epoxy Modified Polymethylpenylsiloxane Emulsions for Oil Agent in Carbon Fibers Production with Different Epoxy Content to Improve the Thermal Stability and Decrease the Surface Tension. Silicon, [PMID:] [10.1007/s12633-024-03159-6] |
| 9. Qiuxue Zhang, Yunjiao Deng, Zhongyu Fu, Shuangquan Wang, Chao Zhou, Huixuan Zhang. (2025) Polyether-epoxy modified polymethylphenylsiloxane emulsions for oil agent in PAN precursors production to improve the hydrophilicity and decrease the hydrodynamic size. Materials Today Communications, [PMID:] [10.1016/j.mtcomm.2025.112357] |
