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· · COA & SDS available for every product · Same-day shipping on in-stock items 4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)quinolin-2(1H)-one , Calcium-activated potassium channel subunit alpha-1 activator, CAS No.275375-69-4, Calcium-activated potassium channel subunit alpha-1 activator
Synonyms
BMS-223131 | (-)-4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)quinolin-2(1H)-one | 2(1H)-Quinolinone, 4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)- | 889F719S7K | QESHSZWKJULSAR-UHFFFAOYSA-N | 4-(5-chloro-2-hyd
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Why this grade for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Room temperature Ships Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
BMS-223131 | (-)-4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)quinolin-2(1H)-one | 2(1H)-Quinolinone, 4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)- | 889F719S7K | QESHSZWKJULSAR-UHFFFAOYSA-N | 4-(5-chloro-2-hyd
Mechanism of action
Calcium-activated potassium channel subunit alpha-1 activator
Product Properties Names and Identifiers Canonical Smiles C1=CC2=C(C=C1C(F)(F)F)C(=C(C(=O)N2)CCO)C3=C(C=CC(=C3)Cl)O IUPAC Name 4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)-1H-quinolin-2-one InChIKey QESHSZWKJULSAR-UHFFFAOYSA-N INCHI 1S/C18H13ClF3NO3/c19-10-2-4-15(25)13(8-10)16-11(5-6-24)17(26)23-14-3-1-9(7-12(14)16)18(20,21)22/h1-4,7-8,24-25H,5-6H2,(H,23,26) Isomeric SMILES C1=CC2=C(C=C1C(F)(F)F)C(=C(C(=O)N2)CCO)C3=C(C=CC(=C3)Cl)O Molecular Weight 383.7 Reaxy-Rn 9440784 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9440784&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Quinolines and derivatives Subclass Phenylquinolines Intermediate Tree Nodes Not available Direct Parent Phenylquinolines Alternative Parents Phenylpyridines Hydroquinolones Hydroquinolines P-chlorophenols Pyridinones 1-hydroxy-2-unsubstituted benzenoids Chlorobenzenes Aryl chlorides Heteroaromatic compounds Lactams Azacyclic compounds Organic oxides Hydrocarbon derivatives Organochlorides Organofluorides Organonitrogen compounds Alkyl fluorides Primary alcohols Molecular Framework Aromatic heteropolycyclic compounds Substituents Phenylquinoline - 4-phenylpyridine - Dihydroquinolone - Dihydroquinoline - 4-halophenol - 4-chlorophenol - Chlorobenzene - Halobenzene - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Pyridinone - Benzenoid - Aryl chloride - Pyridine - Aryl halide - Monocyclic benzene moiety - Heteroaromatic compound - Lactam - Azacycle - Hydrocarbon derivative - Organohalogen compound - Organochloride - Organic oxygen compound - Alkyl halide - Organic nitrogen compound - Alkyl fluoride - Alcohol - Organofluoride - Organonitrogen compound - Primary alcohol - Organooxygen compound - Organic oxide - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as phenylquinolines. These are heterocyclic compounds containing a quinoline moiety substituted with a phenyl group. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Solution Calculators Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
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