6-Azido-hexylamine , CAS No.349553-73-7

CAS: 349553-73-7 Cat. No.: A649060 Molecular Weight: 142.21 EC Number: 801-673-0 PubChem CID: 12034568

Synonyms

EN300-151577 | C6H14N4 | 6-Azido-1-hexanamine | DTXSID20476243 | HY-138387 | AS-36161 | LCZC435 | 6-azidohexylamine | 6-AZIDO-HEXYLAMINE | F1905-6479 | MFCD07369845 | BP-23965 | REF DUPL: 6-Azido-Hexylamine | FT-0685278 | SCHEMBL14009110 | 6-azidohexan-1-

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

6-Azido-hexylamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Liquid

IC50& Target:Cleavable

Specifications

Synonyms

EN300-151577 | C6H14N4 | 6-Azido-1-hexanamine | DTXSID20476243 | HY-138387 | AS-36161 | LCZC435 | 6-azidohexylamine | 6-AZIDO-HEXYLAMINE | F1905-6479 | MFCD07369845 | BP-23965 | REF DUPL: 6-Azido-Hexylamine | FT-0685278 | SCHEMBL14009110 | 6-azidohexan-1-

Biochemical and Physiological Mechanisms

6-Azido-hexylamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Storage

Protected from light, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Canonical Smiles: C(CCCN=[N+]=[N-])CCN
• IUPAC Name: 6-azidohexan-1-amine
• InChIKey: CLQMAUAPICAWGT-UHFFFAOYSA-N
• INCHI: 1S/C6H14N4/c7-5-3-1-2-4-6-9-10-8/h1-7H2
• Isomeric SMILES: C(CCCN=[N+]=[N-])CCN
• PubChem CID: 12034568
• Molecular Weight: 142.21

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic 1,3-dipolar compounds
    • Class Allyl-type 1,3-dipolar organic compounds
      • Subclass Azo imides

• Kingdom: Organic compounds
• Superclass: Organic 1,3-dipolar compounds
• Class: Allyl-type 1,3-dipolar organic compounds
• Subclass: Azo imides
• Intermediate Tree Nodes: Not available
• Direct Parent: Azo imides
• Alternative Parents: Azo compounds Organic salts Monoalkylamines Hydrocarbon derivatives Organic cations
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Azo imide - Azo compound - Organic nitrogen compound - Hydrocarbon derivative - Organic salt - Primary amine - Organonitrogen compound - Primary aliphatic amine - Amine - Organic cation - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as azo imides. These are n-Imides of azo compounds, analogous to azoxy compounds, having a delocalized structure.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Molecular Weight: 142.200 g/mol
• XLogP3: 1.600
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 142.122 Da
• Monoisotopic Mass: 142.122 Da
• Topological Polar Surface Area: 40.400 Ų
• Heavy Atom Count: 10
• Formal Charge: 0
• Complexity: 106.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1