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A 804598 - Moligand™, ≥98% , Antagonist of P2X7, CAS No.1125758-85-1, Antagonist of P2X7

A 804598 - Moligand™, ≥98% , Antagonist of P2X7, CAS No.1125758-85-1, Antagonist of P2X7

Name: A 804598 - Moligand™, ≥98% , Antagonist of P2X7, CAS No.1125758-85-1, Antagonist of P2X7
SKU: A287786
Availability: InStock

CAS: 1125758-85-1 Cat. No.: A287786 Summenformel: C₁₉H₁₇N₅ Molekulargewicht: 315.37 EG-Nummer: 802-550-4

COA

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A 804598 - Moligand™, ≥98% CAS No(1125758-85-1) by Aladdin Scientific

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GRADE & PURITY Moligand™ ? ≥98%

Synonyms

N-Cyano-N"-[(1S)-1-phenylethyl]-N'-5-quinolinyl-guanidine | A-804598 | N-Cyano-N′′-[(1S)-1-phenylethyl]-N′-5-quinolinyl-guanidine

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications Namen und Kennungen Documentation Advanced Data 3D-Struktur Zugehörige Ziele (menschlich) Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm) Chemische und physikalische Eigenschaften Lösungsrechner Bewertungen

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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyme

N-Cyano-N"-[(1S)-1-phenylethyl]-N'-5-quinolinyl-guanidine | A-804598 | N-Cyano-N′′-[(1S)-1-phenylethyl]-N′-5-quinolinyl-guanidine

Spezifikationen & Reinheit

Moligand™, ≥98%

Biochemische und physiologische Mechanismen

Potent, competitive P2X7receptor antagonist (IC50values are 8.9, 9.9 and 10.9 nM for mouse, rat and human P2X7receptors respectively). Selective for P2X7receptors (IC50> 5-10μM for a wide array of cell surface receptors and ion channels). Binds with high

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Aktionsart

ANTAGONIST

Mechanismus der Wirkung

Antagonist of P2X7

Reinheit

≥98%

Namen und Kennungen

Pubchem Sid	504771149
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504771149
Kanonisches Lächeln	CC(C1=CC=CC=C1)N=C(NC#N)NC2=CC=CC3=C2C=CC=N3
IUPAC Name	1-cyano-2-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine
InChIKey	PQYCRDPLPKGSME-AWEZNQCLSA-N
INCHI	1S/C19H17N5/c1-14(15-7-3-2-4-8-15)23-19(22-13-20)24-18-11-5-10-17-16(18)9-6-12-21-17/h2-12,14H,1H3,(H2,22,23,24)/t14-/m0/s1
Isomere SMILES	C[C@@H](C1=CC=CC=C1)N=C(NC#N)NC2=CC=CC3=C2C=CC=N3
Molekulargewicht	315.37
Reaxy-Rn	31636225
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=31636225&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D-Struktur

Zugehörige Ziele (menschlich)

P2RX7 Tchem P2X purinoceptor 7 (4 Activities)

Discover Target: P2RX7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number	Certificate Type	Datum	Artikel
B2218322	Certificate of Analysis	Dec 17, 2024	A287786
B2218335	Certificate of Analysis	Dec 17, 2024	A287786

Chemische und physikalische Eigenschaften

Löslichkeit	Solvent:DMSO, Max Conc. mg/mL: 31.54, Max Conc. mM: 100
Molekulargewicht	315.400 g/mol
XLogP3	4.000
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	5
Exact Mass	315.148 Da
Monoisotopic Mass	315.148 Da
Topological Polar Surface Area	73.100 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	473.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Lösungsrechner

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Bewertungen

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Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

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